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Sep 12 - Sep 13
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Our top choices for Santiago Este hotels

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.
A restaurant with booths and tables, wooden paneling, and green plants.
A modern hotel with a prominent entrance, outdoor seating area, and a handicap-accessible parking space.
A spacious lobby with a central water feature, multiple seating areas, and a curved ceiling with hanging lights.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
United States
Ismael
NT$2,840
NT$3,123 total
includes taxes & fees
Sep 13 - Sep 14
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.
A building with a curved facade, a balcony with metal railings, and a door with a sign.
A spacious room with a high ceiling, a large window, and a wooden door leading to another area. There are several potted plants and a small table with a vase.
A hallway with a glass partition leading to a dining area, a stone wall, and a metal gate with decorative patterns.

2. Hotel Gran David

Hotel Gran David
Santiago
United States
Roxani
NT$2,293
NT$2,522 total
includes taxes & fees
Sep 13 - Sep 14
Hotel Gran David
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.
A hotel room with a dark wooden desk, two cushioned chairs, a large mirror, and two table lamps.
A hotel room with two single beds, a desk with a chair, a television, and a door.
A bathroom with a tiled shower wall, a sink, and a towel rack.

3. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
United States
James
NT$1,636
NT$1,799 total
includes taxes & fees
Sep 13 - Sep 14
Hotel Plaza Los Tucanes
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
A hammock suspended between two white walls in a room with a balcony.
A spacious dining area with high ceilings, large windows, and natural light. Tables are set with chairs and centerpieces.
A multi-story hotel with balconies, a pool, and a reflection in the water.

4. HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
United States
Hedwig
NT$2,414
NT$2,655 total
includes taxes & fees
Sep 13 - Sep 14
HOTEL VISTA LAGO
A beach with a wide sandy shore and gentle waves.
A bedroom with a bed, a chair, a mirror, and an air conditioning unit.
A child crossing a rope bridge over water, with a person assisting.
A building with a thatched roof, a signboard with text, and a parked car.

5. olivias village room

olivias village room
Capellania
NT$1,278
NT$4,671 total
includes taxes & fees
Sep 19 - Sep 20
olivias village room
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Top Santiago Este Hotel Reviews

Hotel Gran David

Hotel Gran David

8/10 Good
"Excelente estacionamiento en la parte de atrás."
Neftali 2-night trip
Posted 2 hours ago
Hotel Gran David
HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"Balcony"
Carmen 1-night trip
Posted 7 days ago
HOTEL VISTA LAGO
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"Excelente"
Olopilel 1-night trip
Posted 3 weeks ago
Hotel Plaza Los Tucanes
Hotel Galería

Hotel Galería

10/10 Excellent
"Hay un restaurante en el hotel con desayuno y comida económica y muy sabrosa. La ubicación del hotel es muy céntrica. Es seguro. Tiene centro comercial al lado. Parqueo de carro seguro. Es perfecto para una visita a Santiago."
Lionel 1-night trip
Posted 5 months ago
Hotel Galería

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Frequently asked questions

Where is the best place for a stay in Santiago Este?
Located 16.2 mi (26.1 km) from the heart of Santiago Este, Hotel Gran David is a top choice for your stay based on our traveler data. Two other options for your stay in the area are Hotel Mykonos Panama and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in Santiago Este.
If I need to cancel my hotel reservation in Santiago Este, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santiago Este.
Where can I learn more about changing or cancelling my trip to Santiago Este?
For additional details about changing or cancelling your trip to Santiago Este, head over to our customer service page.
What is staying in Santiago Este like?
Travelers to Santiago Este will find plenty to explore and enjoy. There are 17 hotels and other accommodations in the surrounding area. Find out more about Santiago Este.
What is there to see in Santiago Este?
Places to visit in the wider area include Los Pozos Termales, Parque Acuatico Italia Guadalupe Panama, and Museum of Salt and Sugar. You'll also find Playa Bella Vista and Stella Sierra Regional Museum in the area. Check out what more to see and do in Expedia's Santiago Este guide.
What's the weather like in Santiago Este?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santiago Este are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.