A densely populated cityscape with a prominent historical building with a dome and bell tower in the foreground.

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Our top choices for Santa Cruz hotels

1. Dos Patios Querétaro Curamoria Collection

Dos Patios Querétaro Curamoria Collection
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (147 reviews)
"Great value, amazing location!"
United States
Thomas
The price is NT$4,087
NT$4,884 total
includes taxes & fees
Jun 30 - Jul 1
Dos Patios Querétaro Curamoria Collection

2. Hotel Suites Sofia

Hotel Suites Sofia
3.0 star property
Santa Cruz
8.4 out of 10, Very Good, (50 reviews)
"Perfect place for our needs"
United States
Joseph
The price is NT$1,821
NT$2,176 total
includes taxes & fees
Jul 8 - Jul 9
Hotel Suites Sofia

3. Cinco de Mayo Hotel

Cinco de Mayo Hotel
2.5 star property
Santa Cruz
7.6 out of 10, Good, (337 reviews)
"Good place for a quick visit."
United States
Josué Elías Pérez
The price is NT$1,020
NT$1,219 total
includes taxes & fees
Jun 30 - Jul 1
Cinco de Mayo Hotel

4. Casa Brunella Hotel Boutique

Casa Brunella Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (258 reviews)
"The hotel is in a great area of Queretaro. It was quiet at night, very clean, beautiful rooms, and friendly staff. Would highly recommend!"
United States
Amy
The price is NT$2,629
NT$3,141 total
includes taxes & fees
Jun 30 - Jul 1
Casa Brunella Hotel Boutique

5. HOTEL & SPA DOÑA URRACA QUERETARO

HOTEL & SPA DOÑA URRACA QUERETARO
4.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (73 reviews)
"Great location and beautiful property. Breakfast was great!"
United States
Claudia
HOTEL & SPA DOÑA URRACA QUERETARO

6. Damián Carmona by Homirent

Damián Carmona by Homirent
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"Todo excelente lo unico que recomendaria que fuera luz calida, la luz blanca fria es muy incomoda. "
Mexico
OSCAR ALEJANDRO
The price is NT$1,158
NT$1,384 total
includes taxes & fees
Jun 30 - Jul 1
Damián Carmona by Homirent

7. Hotel Meson de Isabel

Hotel Meson de Isabel
3.0 star property
Santa Cruz
7.6 out of 10, Good, (79 reviews)
"Good place but for the price definitely not worth it"
United States
Manuel
The price is NT$867
NT$1,036 total
includes taxes & fees
Jun 30 - Jul 1
Hotel Meson de Isabel

8. Casa Realm

Casa Realm
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (40 reviews)
"Nice place to stay "
United States
Oscar
The price is NT$1,524
NT$1,821 total
includes taxes & fees
Jul 13 - Jul 14
Casa Realm

9. Casona 109 By Homirent

Casona 109 By Homirent
3.0 star property
Santa Cruz
The price is NT$1,287
NT$1,902 total
includes taxes & fees
Jun 30 - Jul 1
Casona 109 By Homirent

10. Mesón de San Andrés

Mesón de San Andrés
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (118 reviews)
"This was the perfect hotel for our trip! The staff was very friendly and helpful. Omar answered all of our questions very patiently and gave us great suggestions for things to do and places to visit. It was close enough to walk to the historical center and other attractions. We loved watching the sunset from the rooftop patio and felt like this was our home away from home as we explored the region around Queretaro."
United States
Rachel
The price is NT$1,509
NT$1,803 total
includes taxes & fees
Jun 30 - Jul 1
Mesón de San Andrés

11. Hotel & Spa La Mansión del Burro Azul

Hotel & Spa La Mansión del Burro Azul
3.5 star property
Santa Cruz
8.4 out of 10, Very Good, (452 reviews)
"Excellent"
United States
Rogelio
The price is NT$1,730
NT$2,067 total
includes taxes & fees
Jul 14 - Jul 15
Hotel & Spa La Mansión del Burro Azul

12. Hotel Úrsula Concept

Hotel Úrsula Concept
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (15 reviews)
"It is very clean, the bed was great and all in an historic home that has been converted to a charming family run boutique quality hotel. It is very close to an historic church with its huge plaza filled with families and activities and comfortable benches."
United States
Steven
The price is NT$2,469
NT$2,950 total
includes taxes & fees
Jul 12 - Jul 13
Hotel Úrsula Concept

13. Hotel & Villas HANGAR

Hotel & Villas HANGAR
2.0 star property
20.5 km from Santa Cruz
6.8 out of 10, (32 reviews)
"The total experience was fine for us (2 rooms, 4 people). The only negative is that checking in and out was kind of strange because the person was hidden behind a window. Location was good for commuting back and forth to Univ of Arkansas."
United States
john
The price is NT$1,457
NT$1,741 total
includes taxes & fees
Jun 30 - Jul 1
Hotel & Villas HANGAR

14. HS HOTSSON Hotel Querétaro

HS HOTSSON Hotel Querétaro
4.0 star property
Centro Sur, 4 km from Santa Cruz
9.2 out of 10, Wonderful, (1,002 reviews)
"Nice Hotel good location for us"
United States
Cheryl
The price is NT$4,130
NT$4,935 total
includes taxes & fees
Jul 3 - Jul 4
HS HOTSSON Hotel Querétaro

15. AC Hotel by Marriott Queretaro Antea

AC Hotel by Marriott Queretaro Antea
3.0 star property
Jurica, 10.5 km from Santa Cruz
8.6 out of 10, Excellent, (922 reviews)
"Excelente hotel. "
Mexico
Ricardo
The price is NT$5,069
NT$6,057 total
includes taxes & fees
Jul 3 - Jul 4
AC Hotel by Marriott Queretaro Antea

16. Distrito Hotel Aeropuerto

Distrito Hotel Aeropuerto
3.0 star property
21.2 km from Santa Cruz
The price is NT$2,914
NT$3,482 total
includes taxes & fees
Jul 17 - Jul 18
Distrito Hotel Aeropuerto

17. The Latit Hotel Querétaro

The Latit Hotel Querétaro
3.5 star property
15.5 km from Santa Cruz
8.0 out of 10, Very Good, (634 reviews)
"It was very nice to park in front of my room."
United States
Maria
The price is NT$2,303
NT$2,752 total
includes taxes & fees
Jun 30 - Jul 1
The Latit Hotel Querétaro

18. One Querétaro Aeropuerto Hotel

One Querétaro Aeropuerto Hotel
3.0 star property
17.6 km from Santa Cruz
7.8 out of 10, Good, (1,001 reviews)
"Simple safe and clean. Couldn’t ask for more."
United States
Timothy
The price is NT$2,295
NT$2,743 total
includes taxes & fees
Jul 25 - Jul 26
One Querétaro Aeropuerto Hotel

19. Hotel VIVE MX el marqués Querétaro, Trademark by Wyndham

Hotel VIVE MX el marqués Querétaro, Trademark by Wyndham
3.0 star property
4.2 km from Santa Cruz
9.4 out of 10, Exceptional, (96 reviews)
"Todo excelente!! "
Mexico
Joram
The price is NT$1,806
NT$2,158 total
includes taxes & fees
Jun 30 - Jul 1
Hotel VIVE MX el marqués Querétaro, Trademark by Wyndham

20. Hampton Inn by Hilton Queretaro Tecnologico

Hampton Inn by Hilton Queretaro Tecnologico
3.0 star property
3.7 km from Santa Cruz
8.4 out of 10, Very Good, (1,008 reviews)
"Clean room, staff, breakfast."
United States
Edmundo Luis
The price is NT$1,554
NT$1,857 total
includes taxes & fees
Jul 5 - Jul 6
Hampton Inn by Hilton Queretaro Tecnologico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Cruz

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Breakfast served
Casa Brunella Hotel Boutique
3.5 star property
9.2
Wonderful
258 reviews
View
Interior
Mesón de San Andrés
3.0 star property
9.2
Wonderful
118 reviews
View
Reception
Casa Realm
3.0 star property
9.0
Wonderful
40 reviews
View
Lobby
Dos Patios Querétaro Curamoria Collection
3.5 star property
8.8
Excellent
147 reviews
View
Exterior
Hotel Úrsula Concept
2.5 star property
8.8
Excellent
15 reviews
View

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.

Downtown Querétaro

Downtown Querétaro is known for its abundant dining options, and you can plan a trip to Zenea Garden and Plaza de Armas while you're in town.

Juriquilla

Juriquilla is noteworthy for its restaurants, and you can make a stop at top attractions like Plaza Juriquilla and Plaza Ubika.

Centro Histórico

Unique features of Centro Histórico include the historic sites and museums. Make a stop by Zenea Garden or Plaza de Armas while you're exploring the area.

Downtown Tequisquiapan

You'll enjoy the monuments and shopping in Downtown Tequisquiapan. You might want to make time for a stop at Tequisquiapan Handicraft Market or La Pila Park.

Jurica

Jurica is noteworthy for its shopping, and you can make a stop at top attractions like Antea Lifestyle Center and Urban Center Shopping Mall.

Top Santa Cruz Hotel Reviews

Frequently asked questions

What is Santa Cruz like?
Travelers to Querétaro's Santa Cruz neighborhood will be sure to enjoy a stay in this neighborhood. Are you looking for Santa Cruz travel tips? Be sure to check out Aqueduct of Santiago de Querétaro and Templo y Convento de la Santa Cruz while you're in the neighborhood.
Where is the best place to stay in Santa Cruz?
Based on our traveler data, Hotel Meson de Isabel is one of the top choices for your stay in Santa Cruz. This hotel is a short 12-minute walk from Aqueduct of Santiago de Querétaro, and it offers a restaurant and free WiFi. Other good choices for your stay in the neighborhood include Cinco de Mayo Hotel and Casa Brunella Hotel Boutique.
How many hotels are there in the Santa Cruz area?
Expedia has 49 hotels and other accommodations in Santa Cruz to choose from, making this an ideal home base for exploring the greater Querétaro area.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the top deals on offer in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
For more information about picking new dates or cancelling your trip to Santa Cruz, click here.
What is there to do around this Querétaro neighborhood?
Explore Santa Cruz's landmarks like Aqueduct of Santiago de Querétaro, Templo y Convento de la Santa Cruz, and Arches Viewpoint and learn about the local history. You could also plan a visit to Convent and Temple of Santa Cruz or Querétaro Contemporary Art Museum while you're in the neighborhood. Plaza de Los Fundadores, Casa de la Zacatecana Museum, and Ignacio Mena Rosales House of Culture are just a few of the places to visit in and around Santa Cruz. Plaza de Armas and Querétaro Regional Museum are also worth a visit when you're out sightseeing in Querétaro.