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Our top choices for Santa Cruz hotels

Suites Murillo Plaza Sta Cruz

Suites Murillo Plaza Sta Cruz
3.5 star property
Santa Cruz
9.8 out of 10, Exceptional, (218)
"This hotel is amazing, the location is perfect, from the time we checked in everyone was so nice and helpful. Our room was perfect, the coffee provided was delicious, we had been traveling for a while and this hotel was just what we needed, everything was so comfortable, it was perfect. "
United States
daniel
Suites Murillo Plaza Sta Cruz

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (1002)
"The property had real historic character - in a great location with helpful and friendly staff "
United Kingdom
Caroline Jane
The price is NT$3,663
NT$4,030 total
includes taxes & fees
Jan 19 - 2026/1/20
Las Casas de la Judería, Sevilla Historic City Center

Hotel Amadeus Sevilla

Hotel Amadeus Sevilla
4.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (1107)
"Fantastic stay"
United Kingdom
Amélie
The price is NT$4,113
NT$4,525 total
includes taxes & fees
Jan 8 - 2026/1/9
Hotel Amadeus Sevilla

Hotel Fernando III

Hotel Fernando III
4.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (1529)
"Great location, breakfast & staff "
United States
Anup
Hotel Fernando III

Hotel Alcántara

Hotel Alcántara
2.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (829)
"The staff were friendly, the bathroom was well maintained with thoughtful details, and the room was warm and cozy, allowing me to sleep very well."
United States
Yihan
The price is NT$1,848
NT$2,033 total
includes taxes & fees
Jan 13 - 2026/1/14
Hotel Alcántara

Pensión dulces sueños

Pensión dulces sueños
1.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (52)
"Clean room, location close to the historical landmarks and good eating places close by. Amenities such as a terrace available."
Canada
Hubert
The price is NT$1,543
NT$1,697 total
includes taxes & fees
Jan 8 - 2026/1/9
Pensión dulces sueños

Hotel Boutique Palacio Pinello

Hotel Boutique Palacio Pinello
4.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (685)
"The hotel is centric"
United States
javier
The price is NT$3,327
NT$3,660 total
includes taxes & fees
Jan 11 - 2026/1/12
Hotel Boutique Palacio Pinello

El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique
4.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (895)
"The location is A+! The staff is extremely attentive and knowledgeable their rooms where pristine and comfortable. The bed is very good. Breakfast is amazing. This hotel delivers a great experience."
United States
WALDECTOR
The price is NT$4,204
NT$4,624 total
includes taxes & fees
Jan 8 - 2026/1/9
El Rey Moro Hotel Boutique

Basic Hotel Doña Manuela

Basic Hotel Doña Manuela
2.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (518)
"Clean good staff happy stay great location "
United Kingdom
A. Caroline
Basic Hotel Doña Manuela

Petit Palace Santa Cruz

Petit Palace Santa Cruz
4.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (1001)
"Loved this hotel. Great area"
United States
Kathlyn
The price is NT$2,994
NT$3,294 total
includes taxes & fees
Jan 7 - 2026/1/8
Petit Palace Santa Cruz

Suites Murillo Catedral

Suites Murillo Catedral
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (635)
"Great location and property is clean"
United States
Sreedevi
Suites Murillo Catedral

Eurostars Sevilla Boutique

Eurostars Sevilla Boutique
4.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (492)
"Room was spotless, staff was courteous and location was perfect!"
United States
Andrean
The price is NT$3,529
NT$3,881 total
includes taxes & fees
Jan 15 - 2026/1/16
Eurostars Sevilla Boutique

Basic Hotel Puerta de Sevilla

Basic Hotel Puerta de Sevilla
1.0 star property
Santa Cruz
8.8 out of 10, Excellent, (297)
"Clean room, amenities & wonderful staff especially to Amanda at front desk and housekeeping."
United States
Jose Maria Jeffrey Uy
Basic Hotel Puerta de Sevilla

EME Catedral Mercer Hotel

EME Catedral Mercer Hotel
5.0 star property
Santa Cruz
8.8 out of 10, Excellent, (1000)
"Great location, and thank you to all the staff for making our stay so enjoyable. "
United Kingdom
Samir
The price is NT$6,049
NT$6,654 total
includes taxes & fees
Jan 6 - 2026/1/7
EME Catedral Mercer Hotel

Hotel Rey Alfonso X

Hotel Rey Alfonso X
4.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (1122)
"Lovely hotel in a great location. Friendly staff. Couldn’t be better. "
United States
Alan
The price is NT$8,872
NT$9,759 total
includes taxes & fees
Jan 5 - 2026/1/6
Hotel Rey Alfonso X

Hotel Murillo

Hotel Murillo
2.0 star property
Santa Cruz
8.8 out of 10, Excellent, (1000)
"Staff was very friendly, perfect location can’t get any better than this hotel"
United States
Aldon
Hotel Murillo

Hotel Convento La Gloria

Hotel Convento La Gloria
3.0 star property
Santa Cruz
8.2 out of 10, Very Good, (638)
"* Great staff * Within a short-walk distance to the Cathedral * Good rooftop restaurant with an awesome view of Seville. The tapas bar is also great and prices are good. * Beautiful inside and decoration. "
Canada
Daniel
Hotel Convento La Gloria

Hotel Doña Lina

Hotel Doña Lina
2.0 star property
Santa Cruz
8.6 out of 10, Excellent, (238)
"It' s perfect located also affordable , clean and spacious"
United Kingdom
Adrian
Hotel Doña Lina

Halo Boutique Hotel

Halo Boutique Hotel
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (449)
"Lovely staff, perfect location for the sights of seville"
United Kingdom
Karl
Halo Boutique Hotel

Joya del Casco Boutique Hotel

Joya del Casco Boutique Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (197)
"Staff are excellent and very helpful, hotel in excellent location for sightseeing "
United Kingdom
Sharon
Joya del Casco Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.

Historical Center

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Alfalfa

Unique features of Alfalfa include the bars and historic sites. Make a stop by Salvador Plaza or Calle Sierpes while you're exploring the area.

El Arenal

Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.

Triana

Discover traditional pottery and vibrant flamenco culture in this lively area. Shop at Triana Market for local crafts and tapas, or explore Calle Betis for popular restaurants, bars, and nightclubs.

Sur

Consider exploring the abundant dining options in Sur. If sightseeing is on the list, Plaza de España is a top attraction. Hop on the metro at Gran Plaza or San Bernardo Tram Stop to see more of the area.

Top Santa Cruz Hotel Reviews

Frequently asked questions

What is Santa Cruz like?
Santa Cruz is a historic neighborhood known for its charming cafes and bar scene. Be sure to check out Convent of the Incarnation and Giralda Tower as part of your Santa Cruz travel plans.
What's a favorite place to stay in Santa Cruz?
Based on Expedia customer reviews, Hotel Boutique Casa del Limonero is the highest ranked property in Santa Cruz. This hotel is steps from Giralda Tower, and offers free breakfast and an outdoor pool. Other favorite options in the area include Hotel Boutique Casa del Poeta Sevilla and Joya del Casco Boutique Hotel.
How many hotels will I find in the Santa Cruz area?
If you're searching for places to stay in Paseo de Las Delicias, Expedia has something to meet your needs with 431 Santa Cruz hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best options available in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
For more details about picking new dates or cancelling your trip to Santa Cruz, go to https://www.expedia.com/service/.
What can I see and do in this Paseo de Las Delicias neighborhood?
Explore Santa Cruz's landmarks like Seville Cathedral, Giralda Tower, and General Archive of the Indies and learn about the local history. You could also plan a visit to Convent of the Incarnation or Murillo Gardens while you're in the neighborhood. A few places to visit in the area around Santa Cruz include Archbishop's Palace, Archiddiocesis de Sevilla, and Triunfo Plaza. While you're out sightseeing in Paseo de Las Delicias, be sure to visit other sights like Tumba de Cristóbal Colón or Puerta del Príncipe.
How can I get around Santa Cruz and the greater Paseo de Las Delicias area?
Ready to get out and explore the city? Puerta Jerez Tram Stop is the closest metro station.

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