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Our top choices for Santa Cruz hotels

Suites Murillo Plaza Sta Cruz

Suites Murillo Plaza Sta Cruz
3.5 star property
Santa Cruz
9.8 out of 10, Exceptional, (218)
"This hotel is amazing, the location is perfect, from the time we checked in everyone was so nice and helpful. Our room was perfect, the coffee provided was delicious, we had been traveling for a while and this hotel was just what we needed, everything was so comfortable, it was perfect. "
United States
daniel
Suites Murillo Plaza Sta Cruz

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (1002)
"The property had real historic character - in a great location with helpful and friendly staff "
United Kingdom
Caroline Jane
The price is NT$3,822
NT$4,204 total
includes taxes & fees
Jan 13 - 2026/1/14
Las Casas de la Judería, Sevilla Historic City Center

Hotel Fernando III

Hotel Fernando III
4.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (1529)
"Great location, breakfast & staff "
United States
Anup
The price is NT$3,663
NT$4,030 total
includes taxes & fees
Jan 11 - 2026/1/12
Hotel Fernando III

Hotel Amadeus Sevilla

Hotel Amadeus Sevilla
4.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (1101)
"Fantastic stay"
United Kingdom
Amélie
The price is NT$4,117
NT$4,529 total
includes taxes & fees
Jan 7 - 2026/1/8
Hotel Amadeus Sevilla

Hotel Alcántara

Hotel Alcántara
2.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (829)
"The staff were friendly, the bathroom was well maintained with thoughtful details, and the room was warm and cozy, allowing me to sleep very well."
United States
Yihan
The price is NT$1,682
NT$1,850 total
includes taxes & fees
Jan 6 - 2026/1/7
Hotel Alcántara

El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique
4.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (895)
"The location is A+! The staff is extremely attentive and knowledgeable their rooms where pristine and comfortable. The bed is very good. Breakfast is amazing. This hotel delivers a great experience."
United States
WALDECTOR
The price is NT$4,693
NT$5,162 total
includes taxes & fees
Jan 21 - 2026/1/22
El Rey Moro Hotel Boutique

Hotel Boutique Palacio Pinello

Hotel Boutique Palacio Pinello
4.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (685)
"The hotel is centric"
United States
javier
The price is NT$4,003
NT$4,403 total
includes taxes & fees
Jan 8 - 2026/1/9
Hotel Boutique Palacio Pinello

Eurostars Sevilla Boutique

Eurostars Sevilla Boutique
4.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (490)
"Room was spotless, staff was courteous and location was perfect!"
United States
Andrean
The price is NT$3,148
NT$3,463 total
includes taxes & fees
Jan 28 - 2026/1/29
Eurostars Sevilla Boutique

Petit Palace Santa Cruz

Petit Palace Santa Cruz
4.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (1002)
"Loved this hotel. Great area"
United States
Kathlyn
The price is NT$3,270
NT$3,597 total
includes taxes & fees
Jan 12 - 2026/1/13
Petit Palace Santa Cruz

Basic Hotel Doña Manuela

Basic Hotel Doña Manuela
2.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (518)
"Clean good staff happy stay great location "
United Kingdom
A. Caroline
Basic Hotel Doña Manuela

Suites Murillo Catedral

Suites Murillo Catedral
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (634)
"Great location and property is clean"
United States
Sreedevi
Suites Murillo Catedral

Hotel Convento La Gloria

Hotel Convento La Gloria
3.0 star property
Santa Cruz
8.2 out of 10, Very Good, (638)
"* Great staff * Within a short-walk distance to the Cathedral * Good rooftop restaurant with an awesome view of Seville. The tapas bar is also great and prices are good. * Beautiful inside and decoration. "
Canada
Daniel
Hotel Convento La Gloria

EME Catedral Mercer Hotel

EME Catedral Mercer Hotel
5.0 star property
Santa Cruz
8.8 out of 10, Excellent, (1000)
"Great location, and thank you to all the staff for making our stay so enjoyable. "
United Kingdom
Samir
The price is NT$6,055
NT$6,661 total
includes taxes & fees
Jan 6 - 2026/1/7
EME Catedral Mercer Hotel

Hotel Murillo

Hotel Murillo
2.0 star property
Santa Cruz
8.8 out of 10, Excellent, (1001)
"Staff was very friendly, perfect location can’t get any better than this hotel"
United States
Aldon
Hotel Murillo

La Posada de los Venerables

La Posada de los Venerables
2.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (15)
"Good location and easy access to the hotel."
Sweden
Jessica
La Posada de los Venerables

Joya del Casco Boutique Hotel

Joya del Casco Boutique Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (197)
"Staff are excellent and very helpful, hotel in excellent location for sightseeing "
United Kingdom
Sharon
The price is NT$3,700
NT$4,070 total
includes taxes & fees
Jan 11 - 2026/1/12
Joya del Casco Boutique Hotel

Pensión dulces sueños

Pensión dulces sueños
1.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (52)
"Clean room, location close to the historical landmarks and good eating places close by. Amenities such as a terrace available."
Canada
Hubert
The price is NT$1,544
NT$1,698 total
includes taxes & fees
Jan 8 - 2026/1/9
Pensión dulces sueños

Welldone Cathedral

Welldone Cathedral
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (325)
"Great location, clean room, safe and quiet. "
United States
Yolanda
The price is NT$2,510
NT$2,761 total
includes taxes & fees
Jan 19 - 2026/1/20
Welldone Cathedral

Lukanda Hospec Olehousing

Lukanda Hospec Olehousing
3.0 star property
Santa Cruz
9.8 out of 10, Exceptional, (99)
"Great modern hostel with a spacious room and bathroom. Convenient full kitchen, and nice to enjoy the rooftop terrace"
Canada
Daniela
Lukanda Hospec Olehousing

Halo Boutique Hotel

Halo Boutique Hotel
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (449)
"Lovely staff, perfect location for the sights of seville"
United Kingdom
Karl
Halo Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.

Historical Center

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Alfalfa

Unique features of Alfalfa include the bars and historic sites. Make a stop by Salvador Plaza or Calle Sierpes while you're exploring the area.

El Arenal

Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.

Triana

Discover traditional pottery and vibrant flamenco culture in this lively area. Shop at Triana Market for local crafts and tapas, or explore Calle Betis for popular restaurants, bars, and nightclubs.

Sur

Consider exploring the abundant dining options in Sur. If sightseeing is on the list, Plaza de España is a top attraction. Hop on the metro at Gran Plaza or San Bernardo Tram Stop to see more of the area.

Top Santa Cruz Hotel Reviews

Frequently asked questions

What is Santa Cruz like?
Santa Cruz is a historic neighborhood known for its charming cafes and bar scene. Be sure to check out Convent of the Incarnation and Giralda Tower as part of your Santa Cruz travel plans.
What's a favorite place to stay in Santa Cruz?
Based on Expedia customer reviews, Hotel Boutique Casa del Limonero is the highest ranked property in Santa Cruz. This hotel is steps from Giralda Tower, and offers free breakfast and an outdoor pool. Other favorite options in the area include Hotel Boutique Casa del Poeta Sevilla and Joya del Casco Boutique Hotel.
How many hotels will I find in the Santa Cruz area?
If you're searching for places to stay in Paseo de Las Delicias, Expedia has something to meet your needs with 431 Santa Cruz hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best options available in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
For more details about picking new dates or cancelling your trip to Santa Cruz, go to https://www.expedia.com/service/.
What can I see and do in this Paseo de Las Delicias neighborhood?
Explore Santa Cruz's landmarks like Seville Cathedral, Giralda Tower, and General Archive of the Indies and learn about the local history. You could also plan a visit to Convent of the Incarnation or Murillo Gardens while you're in the neighborhood. A few places to visit in the area around Santa Cruz include Archbishop's Palace, Archiddiocesis de Sevilla, and Triunfo Plaza. While you're out sightseeing in Paseo de Las Delicias, be sure to visit other sights like Tumba de Cristóbal Colón or Puerta del Príncipe.
How can I get around Santa Cruz and the greater Paseo de Las Delicias area?
Ready to get out and explore the city? Puerta Jerez Tram Stop is the closest metro station.

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