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Check prices for these dates

Next weekend
May 22 - May 24
In two weeks
May 29 - May 31

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Our top choices for Santa Cruz de la Sierra hotels

Terrace/patio

Hospedium Hotel Soterraña

Hospedium Hotel Soterraña
3.0 star property
Madronera
8.8 out of 10, Excellent, (38 reviews)
"Tiene aparcamiento propio gratuito, la habitación muy bien y el personal excelente. Si restaurante muy buena calidad y buena atención. "
Spain
Ángel
The price is NT$2,334
NT$2,567 total
includes taxes & fees
May 19 - May 20
Hospedium Hotel Soterraña
Garden

Finca la Desa

Finca la Desa
3.0 star property
Miajadas
10.0 out of 10, Exceptional, (12 reviews)
"Habitacion limpia cómoda. Personal amable."
Spain
Òscar
The price is NT$2,481
NT$2,729 total
includes taxes & fees
May 17 - May 18
Finca la Desa
Exterior

Casa Rural Las Canteras

Casa Rural Las Canteras
3.0 star property
Trujillo
8.2 out of 10, Very Good, (33 reviews)
"Limpieza correcta "
Spain
Carlos
The price is NT$2,967
NT$3,264 total
includes taxes & fees
May 18 - May 19
Casa Rural Las Canteras
Exterior

Finca El Azahar

Finca El Azahar
3.0 star property
Trujillo
10.0 out of 10, Exceptional, (7 reviews)
"Stunning, warm, beautiful, "
Canada
Alex
The price is NT$6,401
NT$7,041 total
includes taxes & fees
Jun 8 - Jun 9
Finca El Azahar
Exterior

Parador de Trujillo

Parador de Trujillo
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (231 reviews)
"Very nice hotel, good parking, well located, "
United States
Edgar
The price is NT$3,089
NT$3,398 total
includes taxes & fees
Jun 3 - Jun 4
Parador de Trujillo
Interior

Plaza Sandra

Plaza Sandra
3.0 star property
Trujillo
9.6 out of 10, Exceptional, (55 reviews)
"Easy to follow check in instructions. Parking on the street nearby. Beautiful property right in the old town. Highly recommended!"
United States
Ismael
The price is NT$2,310
NT$2,541 total
includes taxes & fees
May 18 - May 19
Plaza Sandra
Breakfast, lunch, dinner served; Regional cuisine

Hostal Hueso

Hostal Hueso
2.0 star property
Trujillo
8.2 out of 10, Very Good, (25 reviews)
"Excelent location, excelent staf"
United States
ALFRED
The price is NT$1,834
NT$2,017 total
includes taxes & fees
May 21 - May 22
Hostal Hueso
Restaurant

Hostal León

Hostal León
2.0 star property
Trujillo
7.6 out of 10, Good, (53 reviews)
"Bien "
Spain
Antonio Manuel
The price is NT$1,834
NT$2,017 total
includes taxes & fees
May 19 - May 20
Hostal León
In-room safe, desk, blackout drapes, iron/ironing board

Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (341 reviews)
"Wonderful location. Friendly staff. "
United States
abigail
The price is NT$2,633
NT$2,897 total
includes taxes & fees
Jun 3 - Jun 4
Eurostars Palacio Santa Marta
Ballroom

Hotel Izan Trujillo

Hotel Izan Trujillo
4.0 star property
Trujillo
8.8 out of 10, Excellent, (212 reviews)
"Friendly staff, good buffet breakfast, comfortable room. "
United Kingdom
Malcolm
The price is NT$3,007
NT$3,308 total
includes taxes & fees
May 18 - May 19
Hotel Izan Trujillo
Lunch and dinner served

Hospedium Hotel Triana

Hospedium Hotel Triana
3.0 star property
Miajadas
7.8 out of 10, Good, (19 reviews)
"This is a very convenient stop-over between Santander and Barbate/Vejer/Conil where we were staying. Simple, clean room,super helpful staff and great food at an amazing price. Free car parking in a plot next to the hotel. We've stayed here before and will do so again."
United Kingdom
tina
The price is NT$2,800
NT$3,081 total
includes taxes & fees
May 18 - May 19
Hospedium Hotel Triana
Apartment | Free WiFi, bed sheets

Hostal Ruralis Altozano

Hostal Ruralis Altozano
1.0 star property
Montánchez
9.0 out of 10, Wonderful, (2 reviews)
"Habitacion muy grande, muebles impecables, muy limpia almigualnque el baño. Todo perfecto.hitel.con oarking en centro de Montanchez. Arantxa es magnifica y un encanto. Llegamos muy tarde y nos atendio dejandolo todo preparado. Llaves, telefonos de contacto, etc. REPETIREMOS SIN LUGAR A DUDAS"
Spain
MARCO ANTONIO
The price is NT$1,834
NT$2,017 total
includes taxes & fees
May 17 - May 18
Hostal Ruralis Altozano
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz de la Sierra

Head to Juan Pizarro de Orellana Palace and Plaza Mayor—just two of the sights around Santa Cruz de la Sierra.

See all hotels in Santa Cruz de la Sierra
Catedral de Santa Cruz de la Sierra

Top Santa Cruz de la Sierra Hotel Reviews

Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

10/10 Excellent
"Beautiful hotel in the center of the old town. Staff are superb "
robert 1-night trip
Posted 16 hours ago
Eurostars Palacio Santa Marta

More cheap stays in Santa Cruz de la Sierra

Hostal León

Hostal León

Campillo 11 Trujillo Caceres
The price is NT$1,834 per night from May 19 to May 20
NT$1,834
NT$2,017 total
May 19 - May 20
includes taxes & fees

Frequently asked questions

What's the best place to stay in Santa Cruz de la Sierra?
Eurostars Palacio Santa Marta, located 0.1 mi (0.1 km) from the heart of Santa Cruz de la Sierra, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Parador de Trujillo and Finca la Desa. See all available top hotels, or vacation rentals in Santa Cruz de la Sierra.
If I need to cancel my hotel reservation in Santa Cruz de la Sierra, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz de la Sierra.
Where can I learn more about changing or cancelling my trip to Santa Cruz de la Sierra?
To find more details about updating your trip to Santa Cruz de la Sierra or cancelling it, head over to our customer service page.
What are some accommodations with pools in Santa Cruz de la Sierra?
Eurostars Palacio Santa Marta: Offers complimentary wireless internet access, a seasonal outdoor pool, and televisions. View all hotels with pools in Santa Cruz de la Sierra.
What's the best accommodation near Adolfo Suarez Madrid-Barajas Airport (MAD)?
Madrid Marriott Auditorium Hotel & Conference Center is a popular 4-star hotel featuring 2 restaurants and 2 bars. It's located a short 1.4 mi (2.2 km) from Adolfo Suarez Madrid-Barajas Airport. Other accommodations close to the airport are Hotel Clement Barajas and Meliá Barajas.
What's it like to stay in Santa Cruz de la Sierra?
Those traveling to Santa Cruz de la Sierra are sure to enjoy the sights to see and things to do. In Santa Cruz de la Sierra, there are 9 hotels and other accommodations to choose from. Find out more about Santa Cruz de la Sierra.
What is there to see in Santa Cruz de la Sierra?
Places to visit in the wider area include Juan Pizarro de Orellana Palace, Plaza Mayor, and Trujillo Castle. You'll also find Palacio de la Conquista and Statue of Francisco Pizarro in the area. Check out what more to see and do in Expedia's Santa Cruz de la Sierra guide.
What's the seasonal weather like in Santa Cruz de la Sierra?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 47°F. Average annual precipitation for Santa Cruz de la Sierra is 22 inches.