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Go beyond your typical stay in San Pedro Del Espino

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Pet friendly
Pet friendly
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Pool
Pool

Check prices for these dates

Tonight
Nov 7 - Nov 8
Tomorrow
Nov 8 - Nov 9
Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22

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Our top choices for San Pedro Del Espino hotels

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (605 reviews)
"The service is pretty stable."
United States
Yali
The price is NT$2,513
NT$2,765 total
includes taxes & fees
Nov 8 - Nov 9
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.

2. Hotel Gran David

Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (449 reviews)
"Great place to stay. I would stay there again."
United States
Roxani
The price is NT$2,891
NT$3,180 total
includes taxes & fees
Nov 8 - Nov 9
Hotel Gran David
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.

3. HOTEL VISTA LAGO

HOTEL VISTA LAGO
3.0 star property
La Pena
9.4 out of 10, Exceptional, (128 reviews)
"We went to this hotel for the first time and it’s so amazing, excellent food nothing else to add"
United States
Christian
The price is NT$2,513
NT$2,765 total
includes taxes & fees
Nov 8 - Nov 9
HOTEL VISTA LAGO
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.

4. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
3.0 star property
Nuevo Santiago
8.8 out of 10, Excellent, (16 reviews)
"Clean room, present staff, and in a central área. Doesn’t have hot water BTW"
United States
Alexandria
The price is NT$1,892
NT$2,082 total
includes taxes & fees
Nov 13 - Nov 14
Hotel Plaza Los Tucanes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in San Pedro Del Espino

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

Hotel Mykonos Panama

3.5 star property
Nuevo Santiago
View
A pool surrounded by palm trees and a tiled roof structure.

Hotel Gran David

3.5 star property
Santiago
View
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.

HOTEL VISTA LAGO

3.0 star property
La Pena
View
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.

Hotel Plaza Los Tucanes

3.0 star property
Nuevo Santiago
View
8.8
Excellent
605 reviews
8.6
Excellent
449 reviews
9.4
Exceptional
128 reviews
8.8
Excellent
16 reviews
The price is NT$2,513
NT$2,765 total
includes taxes & fees
Nov 8 - Nov 9
The price is NT$2,891
NT$3,180 total
includes taxes & fees
Nov 8 - Nov 9
The price is NT$2,513
NT$2,765 total
includes taxes & fees
Nov 8 - Nov 9
The price is NT$1,892
NT$2,082 total
includes taxes & fees
Nov 13 - Nov 14
  • Yes, Breakfast included
  • Yes, Pool
  • Yes, Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking

Top San Pedro Del Espino Hotel Reviews

A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
HOTEL VISTA LAGO

HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena

10/10 Excellent

Muy bueno.. solo como feedback un poquito mas de ronda cuando uno esta comiendo y alguien en la piscina por si se quiere pedir algo.. por lo demás todo muy bueno y personas muy amables... volvería!!!!
United States
Sharyn
Reviewed November 4, 2026
HOTEL VISTA LAGO

Frequently Asked Questions

If I need to cancel my hotel reservation in San Pedro Del Espino, will I receive a refund?

Yes! You'll find that most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in San Pedro Del Espino.

Where can I learn more about changing or cancelling my trip to San Pedro Del Espino?

To find more details about changing or cancelling your trip to San Pedro Del Espino, click here.

How is it to stay in San Pedro Del Espino?

Travelers to San Pedro Del Espino will find plenty to explore and enjoy. There are 14 hotels and other accommodations in the surrounding area. Find out more about San Pedro Del Espino.

What is there to see in San Pedro Del Espino?

Places to visit in the wider area include Parque Acuatico Italia Guadalupe Panama, Catedral of Santiago Apostol, and Los Pozos Termales. You'll also find Escuela Normal Juan Demostenes Arosemena and Omar Torrijos Herrera Stadium in the area. Check out what more to see and do in Expedia's San Pedro Del Espino guide.

What's the weather like in San Pedro Del Espino?

The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in San Pedro Del Espino are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.

Where is the best place for a stay in San Pedro Del Espino?

Located 9.5 mi (15.3 km) from the heart of San Pedro Del Espino, Hotel Mykonos Panama is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Hotel Gran David and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in San Pedro Del Espino.

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