The Best Business Hotels in Rochester, MN in 2026

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Our top choices for Rochester business-friendly hotels

1. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

Misty

NT$3,300

NT$3,799 total

includes taxes & fees

Aug 21 - Aug 22

2. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

paul

NT$3,107

NT$4,010 total

includes taxes & fees

Aug 28 - Aug 29

Standard Room, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, cribs (free)

Indoor pool, open 7:00 AM to 11:00 PM, sun loungers

3. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Anne

NT$2,468

NT$2,841 total

includes taxes & fees

Aug 30 - Aug 31

Apartment, 1 Bedroom, 2 Queen Beds, Non Smoking | Premium bedding, down comforters, pillowtop beds, desk

4. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

Luis

NT$2,417

NT$2,782 total

includes taxes & fees

Aug 23 - Aug 24

Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV

Indoor pool, open 5:00 AM to 10:00 PM, sun loungers

5. Hilton Rochester Mayo Clinic Area

Downtown Rochester

Jennifer

NT$5,490

NT$6,320 total

includes taxes & fees

Aug 28 - Aug 29

Studio, 1 Queen Bed | Living area | 40-inch flat-screen TV with digital channels, TV

6. Spark by Hilton Rochester South

Rochester

Susanne

NT$2,601

NT$2,994 total

includes taxes & fees

Aug 23 - Aug 24

Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board

7. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Stephanie

NT$2,947

NT$3,393 total

includes taxes & fees

Aug 21 - Aug 22

Egyptian cotton sheets, premium bedding, pillowtop beds, minibar

8. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

Timothy

NT$3,672

NT$4,227 total

includes taxes & fees

Aug 27 - Aug 28

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Top Rochester Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good

"Clean, nice breakfast"

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"Nice hotel in a great location. They had patio dining. We didn’t get a chance to eat there but would like to the next time we’re in the area. Customer service was excellent! I had an early flight which they accommodated and let me check in early and I was able to take a long nap. Hotel could use a renovation but then rates would be a lot higher. The room was clean and that was what counted the most. The air freshener on the 2nd floor was a little strong for my liking. They had a nice selection for breakfast which was complimentary. The breakfast area was spacious with plenty of room to eat. I would stay here again. Thank you!"

Med City Inn & Suites - Mayo Clinic Area

8/10 Good

"We loved the pool."

Kahler Grand Hotel

10/10 Excellent

"Clean room, location is perfect for visits to Mayo Clinic."

Super 8 by Wyndham Rochester Mayo Clinic Area

10/10 Excellent

"It was a convenient stop on my trip."

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"Easy access yo Mayo Clinic. Right across the street. This is a no frills just hotel spot."

Aspen Select

10/10 Excellent

"It was nice that we could just walk across the street to the hospital each day. Nice and friendly staff!"

Hampton Inn Rochester-South

10/10 Excellent

"Everything functioned as it should."

Brentwood Inn & Suites

8/10 Good

"I find the Brentwood a very good place to stay when I am visiting the Mayo Clinic. My room is always ready when I arrive in town and the staff helpful. The room is clean and adequate for I want for my one-night stay. I particularly like the free or included parking fee and best of all the connection to the subway directly from the hotel. The price point is attractive for the accommodations."

Frequently asked questions

How much do business-friendly hotels in Rochester cost?

Prices for business hotels in Rochester range between and per night. No matter your budget, Expedia can help you find the perfect place to complete the job. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Rochester?

Take your pick of multiple business-friendly hotels in Rochester that have a total average guest review rating of . Hilton Rochester Mayo Clinic Area is a hit with corporate travelers. This 3.5-stars stay features amenities such as a spa and a sauna. Home2 Suites by Hilton Rochester Mayo Clinic Area is another recommended option for a work trip. It has a 3-stars rating and conveniences including private winery tours and pool sun loungers.

How many business-friendly hotels are there in Rochester?

Rochester has hotels that cater to corporate travelers. Whether you're looking for a location closer to the city or conveniences such as workspaces and conference rooms, you'll find the perfect place with Expedia.

What are the best cheap business-friendly hotels in Rochester?

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys is a good pick for corporate travelers after a cost-effective option. It comes with amenities like hypo-allergenic bedding and a cafe. Another economical stay for a work-related trip is Candlewood Suites Rochester Mayo Clinic Area, an IHG Hotel. A barbecue grill and laundry services are among the conveniences available here. Rates for business-friendly hotels in Rochester start at just per night, so you'll have dollars left over to enjoy non-work activities. If you would like to make room for some sightseeing during your work trip to Rochester, there are many terrific free attractions to put on your to-do list. Cascade Lake Beach and National Volleyball Center are worth stopping by. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the top business-friendly motels in Rochester?

About 2 kilometers west of downtown Rochester, Med City Inn & Suites - Mayo Clinic Area is a top choice for corporate guests. Pool sun loungers and a swimming pool are two of the handy amenities at this business-friendly motel. Baymont by Wyndham Rochester Mayo Clinic Area is another great option if you're attending meetings or just need to work remotely in Rochester. Located about 2 kilometers south of the center, a swimming pool and front desk services will help make your stay comfortable.With plenty of cultural, dining and shopping opportunities to enjoy, you might consider extending your work trip to Rochester. Mayowood Mansion and Rochester Civic Theater are fantastic places to get going on your sightseeing adventures.

Are there any family-friendly hotels in Rochester that are also business friendly?

If you're arranging a family trip to Rochester but also need somewhere to work, look up Comfort Inn & Suites West - Medical Center. This 3-stars stay features amenities such as pillow top mattresses and housekeeping services. DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area is another pick that's suited to both business and leisure guests. It has a 4-stars rating and conveniences including a playground and a sauna. Of course, work shouldn't take up all of your time in Rochester! Round up the kids and explore family-friendly attractions, such as Mayowood Mansion and Minnesota Children's Museum.

Are there any 5-star business-friendly hotels in Rochester?

While there are no 5-star business-friendly hotels in Rochester, there are some wonderful 4-star options to pick from. Check out DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area, around 0.16 kilometers from downtown. This stylish home away from home comes with all the conveniences you'll need, like a swimming pool and concierge services. The Towers At Kahler Grand Hotel is another 4-star property that caters to those traveling for work. Around 0.32 kilometers from the center of Rochester, it offers amenities such as a swimming pool and designer toiletries.

Why book your business-friendly hotel in Rochester with Expedia?

Expedia is here to help you find the ideal business-friendly hotel when work takes you on the road. From conference spaces and meeting rooms to gyms and on-site restaurants, our stays have all the amenities you need to get the job done.

How can I find cheap business-friendly hotels in Rochester?

When work takes you on the road in Rochester, our "business friendly" filter will help you find the ideal hotel. From WiFi to workspaces and meeting rooms, they come with the amenities you need for a productive and comfortable stay. You can also narrow your search by your preferred star rating and budget to see the most affordable stays.

What is there to do in Rochester near my business-friendly hotel?

There are plenty of impressive things that'll fill up your itinerary in Rochester. Head for renowned attractions like Mayowood Mansion, Rochester Civic Theater and Minnesota Children's Museum. Cascade Lake Beach, History Center of Olmsted County and Mayo Civic Center are other must-do's.

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Change your mind

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Check availability on Rochester Business Hotels

Our top choices for Rochester business-friendly hotels

1. Hotel Indigo Rochester – Mayo Clinic Area by IHG

2. EVEN Hotel Rochester - Mayo Clinic Area by IHG

3. Comfort Inn & Suites Rochester South Mayo Clinic