Located close to Durham Performing Arts Center, Residence Inn Durham McPherson/Duke University Medical Cntr provides free to-go breakfast, a free grocery shopping service, and a terrace. Free in-room WiFi is available to all guests, along with dry cleaning/laundry services and a fireplace in the lobby.
Located in Trinity Park, a neighborhood in Durham, Residence Inn Durham McPherson/Duke University Medical Cntr is near a train station. Streets at Southpoint Mall and Brier Creek Commons are worth checking out if shopping is on the agenda, while those wishing to experience the area's popular attractions can visit Durham Performing Arts Center. Sarah P. Duke Gardens and Museum of Life and Science are also worth visiting. Visit our Durham travel guide
1108 West Main Street, Durham, NC, 27701
What's nearby
Brightleaf Square
3 min walk - 0.3 km
Duke University
3 min walk - 0.3 km
Carolina Theatre
12 min walk - 1.1 km
Durham Convention Center
12 min walk - 1.1 km
Durham Performing Arts Center
16 min walk - 1.4 km
Getting around
Durham Station
8 min walk
Raleigh-Durham International Airport (RDU)
21 min drive
Restaurants
Atomic Clock Brewing Co
11 min walk
Dakine's Kava
11 min walk
Grub Durham
12 min walk
The Federal
3 min walk
Narrative Coffee Company
13 min walk
About this property
Residence Inn Durham McPherson/Duke University Medical Cntr
Hotel remodeled in 2024 and located near Duke University
Located close to Durham Performing Arts Center, Residence Inn Durham McPherson/Duke University Medical Cntr provides free to-go breakfast, a free grocery shopping service, and a terrace. In addition to dry cleaning/laundry services and a fireplace in the lobby, guests can connect to free in-room WiFi.
Other perks include:
A free area shuttle, self parking (surcharge), and express check-out
Express check-in, wedding services, and smoke-free premises
Coffee/tea in the lobby, luggage storage, and concierge services
Guest reviews speak highly of the helpful staff
Room features
All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches like free WiFi and desk chairs.
Extra conveniences in all rooms include:
Shower/tub combinations, free toiletries, and hair dryers
32-inch Smart TVs with Netflix and premium channels
Wardrobes/closets, separate sitting areas, and recycling
Awards and affiliations
Sustainability Certifications
This property is certified by this third-party sustainability certification scheme: LEED - Leadership in Energy and Environmental Design. For more information on what this certification requires and verifies, please visit their website.
Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?
Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 100 lbs per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?
As of 2026/10/24, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on 2026/11/22 start from NT$4,848, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking?
Self parking is available for USD 15 per day.
What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?
Check-in start time: 3 PM; Check-in end time: midnight.
What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?
Check-out is at noon.
Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?
Located in Trinity Park, this hotel is within 1 mi (2 km) of Brightleaf Square, Duke University, and Durham Performing Arts Center. Carolina Theatre and Durham Convention Center are also within 15 minutes. Durham Station is 8 minutes by foot.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Residence Inn Durham McPherson/Duke University Medical Cntr Reviews
9.0
Wonderful
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
Really convenient central hotel and a reasonable price during the week. Loved having a kitchenette and seating area in the studio. Very comfortable and quiet.
Clean, spacious rooms with an extremely helpful staff! Highly recommended!!
Stayed 3 nights in Apr 2026
Verified review
8/10 Good
Sarah
2026/7/19
Liked: Cleanliness, staff & service, amenities
Room was clean. Comfortable bed. Basic hotel breakfast. Lots of parking. Had A/C issue quickly resolved by a really nice technician. Close to 9th St where there’s lots of restaurants. Vin Rouge was delicious and JuJu. Would stay here again.
The rooms are spacious and the location is great in downtown Durham. Easy walk to Duke east. Several good restaurants and ice cream are just a block away. There's a charge for parking here. Breakfast was tasty. I would stay here again.
Excellent breakfast. The staff was outstanding. The room's television did not work the first night and the front desk clerk spent extensive time troubleshooting and escalating the outage. The room's heating, cooling and fan did not respond to the in-room thermostat.
Stayed 2 nights in Jul 2026
Verified review
6/10 Okay
Irena
2026/6/14
Liked: Staff & service
Disliked: Amenities
Good location.
Poorly designed rooms.
Poor cleaning.
Good breakfast.
Good parking.
Efficient staff -Daniasia was very helpful.
Overall it was a decent and very nice review 54 stars because the hotel was so clean and nice. Vincent Jackson room 322.hotel, the breakfast was very good and everyone was pleasant and friendly; however, I found the mattress in my room to be hard and uncomfortable, after talking to staff they put a softer cover on the bed that helped some but that wasn't until the last night of a 3 night stay.theere was no hot water in my room for the entire stay,I had to revert back to my old military days and wash accordingly. I let the hotel receptionist know of this many times but nothing was ever done about it. Iwas surprised because I never experienced this ever at a residence inn anywhere before. I was not offered any room rate reduction or compensation, I found this to be a bit strange. I still give a 4 star re irw
I had a great stay overall. The service was excellent, and the staff was incredibly friendly, welcoming, and helpful throughout my visit. They really made the experience enjoyable. Rooms are spacious and beds are comfortable.
The only area that could use improvement is the breakfast. The selection was very basic, mostly eggs and pork options, with limited healthier choices available. The fruit also did not seem very fresh. I think revamping the breakfast menu with fresher ingredients and more healthy variety would make the stay even better.
Despite that, I would still recommend this hotel because the customer service was outstanding.