A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

Find hotels in Puxico, MO from NT$1,883

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Puxico hotels

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

1. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (975 reviews)
"Everything was great- breakfast, cleanliness, price— will stay there again"
United States
ELAINE
The price is NT$3,159
NT$3,569 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Poplar Bluff
A modern lounge area with seating arrangements, a kitchen area, and a bar.

2. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.6 out of 10, Exceptional, (81 reviews)
"This place is Brand new and really great!"
United States
Bryan
The price is NT$3,181
NT$3,604 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn By Hilton Dexter
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

3. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,000 reviews)
"Everything was great about the stay!"
United States
Denise
The price is NT$2,937
NT$3,289 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn Poplar Bluff
A spacious lobby with a reception desk, seating area, and large windows.

4. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean, great food, excellent staff."
United States
Dean
The price is NT$2,928
NT$3,308 total
includes taxes & fees
Nov 13 - Nov 14
Drury Inn & Suites Poplar Bluff
A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

5. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (424 reviews)
"Staff was very friendly"
United States
Steven
The price is NT$2,818
NT$3,193 total
includes taxes & fees
Nov 8 - Nov 9
Travelodge by Wyndham Dexter
A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

6. Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (288 reviews)
"The place was okay for a night"
United States
Herman
The price is NT$1,662
NT$1,883 total
includes taxes & fees
Nov 29 - Nov 30
Econo Lodge Dexter
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

7. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very good, (1,002 reviews)
"Rooms were large and clean. Bathroom was large with a nice shower. Parking was convenient Would definitely stay again."
United States
Jim
The price is NT$2,314
NT$2,591 total
includes taxes & fees
Nov 13 - Nov 14
Motel 6 Poplar Bluff, MO
A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

8. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
Poplar Bluff
7.8 out of 10, Good, (443 reviews)
"Excellent every things"
United States
Muhammad
The price is NT$2,425
NT$2,740 total
includes taxes & fees
Nov 22 - Nov 23
Comfort Inn Poplar Bluff North
A Holiday Inn hotel with a covered entrance, multiple floors, and a parking lot.

9. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (799 reviews)
"Always an enjoyable stay"
United States
Nathan
The price is NT$2,575
NT$2,909 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Poplar Bluff by IHG
A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

10. OYO Hickory House Inn

OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (147 reviews)
"Great staff! Clean rooms and convinient"
United States
DIEGO
The price is NT$1,654
NT$2,040 total
includes taxes & fees
Nov 30 - Dec 1
OYO Hickory House Inn
A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

11. Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (373 reviews)
"breakfast was good, staff friendly, pool area needs work"
United States
Edward
The price is NT$2,245
NT$2,544 total
includes taxes & fees
Nov 1 - Nov 2
Dexter Inn
A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

12. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (679 reviews)
"I stay here quite often when I come into town, most the time room is clean and fresh, this time the room had a urine smell, the bed needed repair or replaced, there was an issue with expedia and I got charged twice but expedia did refund the money. Overall disappointed with this stay and will start staying at the drury from now on."
United States
Michael
The price is NT$2,134
NT$2,410 total
includes taxes & fees
Nov 25 - Nov 26
Super 8 by Wyndham Poplar Bluff Missouri
A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

13. Lake Wappapello

Lake Wappapello
2.0 star property
Williamsville
9.4 out of 10, Exceptional, (6 reviews)
"Pet friendly. Family-friendly "
United States
Tonya
The price is NT$2,929
NT$3,089 total
includes taxes & fees
Nov 5 - Nov 6
Lake Wappapello
A living room with a blue wall, a fireplace, a sofa, and a chair.

14. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (117 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
United States
Jan
The price is NT$3,421
NT$3,724 total
includes taxes & fees
Nov 15 - Nov 16
EC Reed's Mercantile and Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Puxico

Check out the local area in Puxico—home to attractions like Mark Twain National Forest and Mingo Wilderness.

See all hotels in Puxico
A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.
Photo by Mike McClain
Open Photo by Mike McClain

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"All good!"
Phillip 1-night trip
Posted 14 hours ago
Hampton Inn Poplar Bluff

More cheap stays in Puxico

Econo Lodge Dexter

Econo Lodge Dexter

913 Outer Rd Dexter MO
The price is NT$1,662 per night from Nov 29 to Nov 30
NT$1,662
NT$1,883 total
Nov 29 - Nov 30
includes taxes & fees

Hotels in Puxico with star-rating

Frequently asked questions

What's the best place for a stay in Puxico?
Holiday Inn Poplar Bluff by IHG, located 18.8 mi (30.3 km) from the heart of Puxico, is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Hampton Inn Poplar Bluff and Motel 6 Poplar Bluff, MO. See all available top hotels, or vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
Where can I learn more about changing or cancelling my trip to Puxico?
To find more details about picking new dates or cancelling your trip to Puxico, click here.
What is staying in Puxico like?
Travelers to Puxico will find plenty to explore and enjoy. There are 52 hotels and other accommodations in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favorite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Check out what more to see and do in Expedia's Puxico guide.
What's the seasonal weather like in Puxico?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Puxico is 59 inches.

Explore a world of travel with Expedia