Photo by Mike McClain

Find hotels in Puxico, MO from NT$1,733

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Compare 54 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (695)
"Amazing place"
United States
Mladen
The price is NT$3,118
NT$3,522 total
includes taxes & fees
Dec 4 - Dec 5
Holiday Inn Poplar Bluff by IHG
Seasonal outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas
Dexter Inn

Dexter Inn

2.5 star property
Dexter
7.0 out of 10, Good, (332)
"Room was nice and spacious."
United States
Rebecca
The price is NT$2,037
NT$2,287 total
includes taxes & fees
Dec 3 - Dec 4
Dexter Inn
In-room safe, desk, free WiFi, bed sheets
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2.0 star property
Poplar Bluff
6.6 out of 10, (621)
"The lady at the front was very nice. "
United States
Travis
The price is NT$1,681
NT$1,899 total
includes taxes & fees
Dec 17 - Dec 18
Super 8 by Wyndham Poplar Bluff Missouri
Terrace/patio
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (794)
"Staff was kind and provided a lot of information during check out."
United States
Shea
The price is NT$3,118
NT$3,491 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn Poplar Bluff
Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (845)
"Very clean, great check in"
United States
Teresa
The price is NT$3,259
NT$3,682 total
includes taxes & fees
Dec 7 - Dec 8
Fairfield Inn & Suites by Marriott Poplar Bluff
Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (955)
"Delicious, well-ran breakfast and quiet peaceful hotel. "
United States
Janene
The price is NT$2,950
NT$3,333 total
includes taxes & fees
Dec 6 - Dec 7
Drury Inn & Suites Poplar Bluff
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Dexter

Econo Lodge Dexter

2.0 star property
Dexter
6.8 out of 10, (250)
"The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. "
United States
Michelle
The price is NT$1,736
NT$1,949 total
includes taxes & fees
Dec 31 - 2026/1/1
Econo Lodge Dexter
Lobby
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1009)
"Check in was smooth and facilities are excellent "
United States
Hector
The price is NT$2,386
NT$2,516 total
includes taxes & fees
Dec 6 - Dec 7
Motel 6 Poplar Bluff, MO
Breakfast, lunch, dinner served; American cuisine
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

2.0 star property
Dexter
7.6 out of 10, Good, (380)
"Sweet"
United States
Jeffrey
The price is NT$2,829
NT$3,176 total
includes taxes & fees
Dec 4 - Dec 5
Travelodge by Wyndham Dexter
Lobby
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2.5 star property
Poplar Bluff
7.8 out of 10, Good, (396)
"Good breakfast selection for the price and clean room. "
United States
Jared
The price is NT$2,829
NT$3,196 total
includes taxes & fees
Dec 7 - Dec 8
Comfort Inn Poplar Bluff North
Fountain
Bullwinkles Rustic Lodge

Bullwinkles Rustic Lodge

2.5 star property
Poplar Bluff
8.4 out of 10, Very Good, (210)
"Room was not clean, one bath towel for two people, no hand tools or wash cloths, no hand soap or shampoo. Parking is not the best. Could hear person next door snoring all night. For anyone expecting to eat breakfast early then take off you will have to wait until 9:00 am because the lobby doesn’t open until then so you can eat. "
United States
Floyd
Bullwinkles Rustic Lodge
Studio, 1 King Bed
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 star property
Dexter
10.0 out of 10, Exceptional, (1)
"Staff was helpful and professional. The rooms were clean and comfortable "
United States
Michael
The price is NT$3,170
NT$3,559 total
includes taxes & fees
Jan 1 - 2026/1/2
Hampton Inn By Hilton Dexter
Exterior
OYO Hickory House Inn

OYO Hickory House Inn

2.5 star property
Dexter
5.4 out of 10, (128)
"Courteous staff"
United States
GEORGE
The price is NT$1,375
NT$1,733 total
includes taxes & fees
Dec 31 - 2026/1/1
OYO Hickory House Inn
Deluxe Double Room | Premium bedding, individually decorated, individually furnished
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (83)
"Cute room, great food, fun soda fountain and friendly owners! Will return! "
United States
Leslie
EC Reed's Mercantile and Hotel
Front of property
Lake Wappapello

Lake Wappapello

2.0 star property
Williamsville
10.0 out of 10, Exceptional, (1)
"We did loose internet connection so gps did not always help but the local stores did. Also the managers answered their phones and were so helpful in many ways! I’m very glad we went."
United States
Dyann
The price is NT$4,332
NT$4,569 total
includes taxes & fees
Dec 10 - Dec 11
Lake Wappapello
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Puxico

Check out the local area in Puxico—home to attractions like Mark Twain National Forest and Mingo Wilderness.

See all hotels in Puxico
Great place for sunrises, Bald Eagles in the winter, and Milkyway shots.
Photo by Mike McClain
Open Photo by Mike McClain

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"Very nice room and staff."
Annette 2-night trip
Posted 4 days ago
Hampton Inn Poplar Bluff

More cheap stays in Puxico

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO
The price is NT$2,386 per night from Dec 6 to Dec 7
NT$2,386
NT$2,516 total
Dec 6 - Dec 7
includes taxes & fees
7.8/10 Good! (1,009 reviews)

Hotels in Puxico with star-rating

Frequently asked questions

What's the best place for a stay in Puxico?
Motel 6 Poplar Bluff, MO, located 19.4 mi (31.3 km) from the heart of Puxico, is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Holiday Inn Poplar Bluff by IHG and Fairfield Inn & Suites by Marriott Poplar Bluff. See all available top hotels, or vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
Where can I learn more about changing or cancelling my trip to Puxico?
To find more details about picking new dates or cancelling your trip to Puxico, click here.
What is staying in Puxico like?
Travelers to Puxico will find plenty to explore and enjoy. There are 53 hotels and other accommodations in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favorite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Check out what more to see and do in Expedia's Puxico guide.
What's the seasonal weather like in Puxico?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Puxico is 59 inches.

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