Photo by Russell Hewatt

Find hotels in Panacea, FL from NT$2,769

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 491 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Panacea Motel

2.0 star property
9.0 out of 10, Wonderful, (104)
"We absolutely loved this quaint little motel. It was very clean and quiet. The staff was very friendly and accommodating. We will definitely be returning."
The Panacea Motel

The Lodge at Wakulla Springs

3.0 star property
9.2 out of 10, Wonderful, (955)
"Very clean and well maintained. All staff were super friendly. I would stay here again."
The Lodge at Wakulla Springs

Wildwood Inn

3.0 star property
8.6 out of 10, Excellent, (1004)
"An enjoyable stay. Thank you."
The price is NT$3,342
NT$3,845 total
includes taxes & fees
Aug 10 - Aug 11
Wildwood Inn

Best Western Wakulla Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (912)
"We absolutely love this venue and stay here when we visit our family every year! "
The price is NT$3,416
NT$3,808 total
includes taxes & fees
Aug 10 - Aug 11
Best Western Wakulla Inn & Suites

St James Bay Golf & Pickleball Resort

3.5 star property
9.0 out of 10, Wonderful, (345)
"The resort was very pretty. Grounds are well kept. Facilities are in nice condition. Pretty cool that you have your own washer/dryer in the villas. If you want a beach, there isn't too much close by. Carrabelle beach is about 20 minutes away, nice, but small, and no shops or restaurants near. St. George Island is about 30 minutes. Worth the drive. Good beach, lots of shops, lighthouse & museum, etc."
The price is NT$4,682
NT$5,173 total
includes taxes & fees
Aug 3 - Aug 4
St James Bay Golf & Pickleball Resort

The Moorings Hotel and Marina

2.5 star property
8.4 out of 10, Very Good, (33)
"Loved the view of the marina from our room"
The price is NT$5,314
NT$5,872 total
includes taxes & fees
Aug 4 - Aug 5
The Moorings Hotel and Marina

Franklin Inn

2.0 star property
7.8 out of 10, Good, (424)
"The Franklin Inn is a frequent go to. The staff is always welcoming and helpful. This is a convenient, clean, maintained, and reasonable stay."
The price is NT$2,769
NT$3,060 total
includes taxes & fees
Jul 29 - Jul 30
Franklin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Panacea attractions

Learn more about Panacea

Experience relaxing Panacea: its beaches, fishing, sunsets, and more!

Top Panacea Hotel Reviews

Frequently asked questions

Where is the best place to stay in Panacea?

Expedia customers give high marks to The Panacea Motel. See all available top hotels, or vacation rentals in Panacea.

If I need to cancel my hotel reservation in Panacea, will I receive a refund?

Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.

Where can I learn more about changing or cancelling my trip to Panacea?

For more details about changing or cancelling your trip to Panacea, click here.

What's the best pet-friendly place to stay in Panacea?

The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.

Where is the best hotel to stay with easy access to USS Mohawk CGC Veterans Memorial Reef?

Best Western Wakulla Inn & Suites is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. You'll find it 5.7 mi (9.1 km) from USS Mohawk CGC Veterans Memorial Reef. Another good option is Magnuson Hotel Wildwood Inn, located 6.5 mi (10.5 km) away.

What's the best hotel for staying near Tallahassee Regional Airport (TLH)?

Tallahassee Sun & Moon is one of the top choices for your stay and is a popular property, featuring free WiFi and free parking. It's located 3.5 mi (5.7 km) from Tallahassee Regional Airport. Other options close to the airport include Hampton Inn & Suites Tallahassee Capitol-University and Governors Inn.

What's it like to stay in Panacea?

Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 201 hotels and other accommodations to choose from. Find out more about Panacea.

What are the top places to visit in Panacea?

Natural beauty is on display at Mashes Sand Beach, Wilson Beach, and Alligator Point Beach. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Bald Point State Park and Public Beach Access. Check out what more to see and do in Expedia's Panacea guide.

What's the seasonal weather like in Panacea?

The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.