Find hotels in Panacea, FL from NT$3,254

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Compare 497 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Panacea Motel

2.0 star property
Panacea
9.0 out of 10, Wonderful, (135)
"A v nice place to stay "
United States
Harry
The Panacea Motel

The Lodge at Wakulla Springs

3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1000)
"Everything about our stay was great! Location, The Lodge, Staff, The food was excellent, and the staff. We only stayed one night as a halfway trip to Disney, but we will definitely be back because our family loved it so much!"
United States
Kaitlyn
The Lodge at Wakulla Springs

Wildwood Inn

3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1002)
"Clean, friendly staff, good location. "
United States
Jennifer
The price is NT$3,596
NT$4,134 total
includes taxes & fees
Dec 18 - Dec 19
Wildwood Inn

Best Western Wakulla Inn & Suites

2.5 star property
Crawfordville
8.8 out of 10, Excellent, (945)
"Great hotel. Very good customer service and very clean"
United States
claudina
The price is NT$3,482
NT$3,883 total
includes taxes & fees
Jan 1 - 2026/1/2
Best Western Wakulla Inn & Suites

St James Bay Golf & Pickleball Resort

3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (366)
"The facility and amenities were wonderful! Everyone was so friendly and helpful. Our pup enjoyed his stay also. We will be back for sure! "
United States
Amy
The price is NT$4,416
NT$4,879 total
includes taxes & fees
Jan 1 - 2026/1/2
St James Bay Golf & Pickleball Resort

The Moorings Hotel and Marina

2.5 star property
Carrabelle
8.4 out of 10, Very Good, (39)
"Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!"
United States
Cheryl
The price is NT$4,322
NT$4,776 total
includes taxes & fees
Dec 8 - Dec 9
The Moorings Hotel and Marina

The Old Carrabelle Hotel

2.0 star property
Carrabelle
The price is NT$4,478
NT$4,949 total
includes taxes & fees
Jan 1 - 2026/1/2
The Old Carrabelle Hotel

Franklin Inn

2.0 star property
Carrabelle
7.8 out of 10, Good, (453)
"JJ was great great location clean room comfortable bed and good value. "
United States
Crystal
The price is NT$2,945
NT$3,254 total
includes taxes & fees
Jan 2 - 2026/1/3
Franklin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Panacea attractions

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

Sunset over a lake at Panacea, northern Florida, USA | NONE |

Top Panacea Hotel Reviews

More cheap stays in Panacea

Hotels in Panacea with star-rating

Find out more about Panacea

Top reasons to visit Panacea

  • Stunning Beaches: Panacea boasts beautiful, secluded beaches where visitors can relax and enjoy breathtaking ocean views.
  • Outdoor Adventures: The area offers numerous recreational activities, including hiking, fishing, and golfing in picturesque settings.
  • Nearby State Parks: Explore nearby state parks that showcase Florida's natural beauty and diverse wildlife.
  • Charming Accommodations: Choose from a variety of cozy motels and guesthouses, many with pet-friendly options and beach access.
  • Friendly Locals: Experience the warm hospitality of the locals, enhancing your visit to this hidden gem.

Find great hotels near Panacea

In Panacea, Florida, you'll discover a variety of accommodations, from cozy motels to welcoming guesthouses, perfect for family vacations or adventure seekers. With pet-friendly options and easy access to the beach, you can enjoy a relaxing getaway tailored to your needs. Whether you're searching for the best Panacea hotels, reading reviews, or looking for beachfront motels, this charming destination has something for everyone.

  • Hyatt House Tallahassee Capitol – University: A welcoming 3-star hotel set 46.7km from Panacea, Hyatt House Tallahassee Capitol – University is ideal for families and business travelers alike. This pet-friendly accommodation offers a range of amenities tailored for children, including complimentary cribs and safety features like window guards. With a focus on comfort and practicality, guests can enjoy spacious rooms and a relaxed atmosphere, making it perfect for both leisure and work-related stays. The hotel also supports pet owners with specific policies and amenities, allowing for a stress-free experience.
  • Best Western Wakulla Inn & Suites: Located a mere 9.7km from Panacea, Best Western Wakulla Inn & Suites is the perfect choice for adventure seekers and business travelers. This hotel provides numerous recreational activities nearby, including boat tours, sailing, and hiking, making it an excellent base for outdoor enthusiasts. With a commitment to customer satisfaction, the hotel offers a comfortable stay with essential amenities that cater to both relaxation and adventure, ensuring you can make the most of your time in the area.
  • Wildwood Inn: Situated 11.3km from Panacea, Wildwood Inn is a charming 3-star hotel that offers a unique blend of adventure and comfort, making it suitable for both families and pet owners. Guests can engage in various outdoor activities such as fishing, snorkeling, and mountain biking, ensuring an exciting stay. The inn welcomes pets with a flexible policy and provides essential amenities for a hassle-free experience. With its friendly atmosphere and proximity to nature, Wildwood Inn is a fantastic choice for those looking to explore the great outdoors while enjoying quality accommodations.

Where to stay in Panacea

Panacea, Florida, is a hidden gem perfect for a serene beach getaway. With its beautiful coastal scenery and oceanfront charm, visitors can unwind in a relaxing atmosphere. Explore nearby towns for family-friendly activities and recreation, where friendly locals enhance your experience. Don't miss the chance to enjoy the secluded beaches and breathtaking views that make Panacea an ideal destination for outdoor enthusiasts and those seeking tranquility.

  • Alligator Point: Nestled along the Gulf Coast, Alligator Point is a charming village that offers a serene beach getaway. The area is less crowded compared to other tourist destinations, making it ideal for those seeking peace and natural beauty. Travelers flock here for the stunning scenery, outdoor activities, and relaxing beach atmosphere. Popular spots include recreational areas, resorts, and a nearby golf course. Attractions such as the beach, national state park, and wetlands provide excellent opportunities for hiking and wildlife observation, ensuring a memorable vacation experience.
  • Saint Teresa: This quaint village is known for its picturesque beaches and vibrant outdoor experiences. Saint Teresa sees moderate seasonal tourism, with visitors particularly drawn to its scenic beauty during the spring and summer months. The area features a variety of recreational areas, resorts, and golf courses, making it perfect for both relaxation and adventure. Notable attractions include the beautiful beaches, national state park, and even a nudist beach for those seeking a unique experience. The welcoming atmosphere and coastal charm make Saint Teresa a delightful stop on your vacation.
  • Ochlockonee Bay: Located along the scenic coastline, Ochlockonee Bay is a hidden gem that captures the essence of Florida's natural beauty. The village experiences steady visitor traffic year-round, with peak seasons in late spring and summer. Known for its outdoor adventures, visitors can enjoy recreational areas, educational opportunities, and local markets. Attractions like the beautiful beaches, national state park, and the winding river provide ample opportunities for kayaking, fishing, and relaxing by the water. With its laid-back vibe and stunning landscapes, Ochlockonee Bay is a great addition to your travel itinerary.

Things to do in and around Panacea

Panacea, Florida, is perfect for beach and outdoor enthusiasts, offering stunning scenery and a variety of activities. Visitors can enjoy recreational areas, relaxing resorts, and golf courses. For the best experiences, explore outdoor seating options and immerse yourself in the natural beauty around you. Whether you're lounging by the beach or hitting the greens, Panacea promises memorable outdoor adventures for everyone.

Shopping

In Panacea, you can explore the local vibe at the Flea Market Tallahassee, located 40.2km away, offering unique finds. If you're up for a drive, check out the Governor's Square Mall and Tallahassee Downtown Market, both 46.7km away, featuring a mix of shopping and entertainment options.

Recreation

St. James Bay Golf Club offers a scenic golfing experience with its lush fairways and vibrant outdoor atmosphere, located 20.9km from Panacea. For relaxation, Woolley Park and Myron B Hodge City Park, both within Panacea, provide tranquil spaces for leisurely strolls and unwinding in nature.

Adventure

Experience the breathtaking scenery along the Tallahassee-Saint Marks Historic Railroad Trail, located 43.5km from Panacea, perfect for hiking enthusiasts. The nearby Tallahassee-St. Marks Historic Railroad State Trail, 46.7km away, and the Saint Marks Trail, 45.1km from Panacea, offer additional adventures amidst nature's beauty.

Nightlife

Experience the vibrant nightlife in Panacea by visiting Theatre Tallahassee, located 49.9km away. Enjoy a romantic evening filled with captivating performances that showcase local culture and entertainment, making it a perfect spot for a memorable night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Panacea

When planning your trip to Panacea, Florida, consider visiting during the cheaper months of July and December to January for lower accommodation rates. Mondays are the least expensive days to stay, while Fridays tend to be pricier. Use Expedia to find great deals by filtering for eco-certified hotels and combining hotel bookings with flights for additional savings. Explore free local attractions and utilize public transportation options to save on travel costs. Always arrange price filters from low to high to discover the best rates.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Panacea are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Panacea is Monday. The most expensive day to stay in Panacea is Friday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to tailor your options based on your budget, preferred location, and desired hotel type. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels currently available. To find the best prices and deals, simply arrange the price filter from low to high.
  • Consider bundling your trip: You can save money by combining your Panacea hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions in Panacea

Panacea, Florida, is an ideal destination for beach lovers and outdoor enthusiasts, offering stunning scenery and a range of attractions. Visitors can enjoy the local beaches, explore nearby state parks, and take a trip to nearby islands. Whether you're looking for relaxation by the shore or adventure in nature, Panacea provides a perfect blend of experiences for travelers seeking outdoor beauty and coastal charm.

  • Alligator Point Beach: Experience the serene beauty of Alligator Point Beach, a perfect spot for sunbathing and beachcombing. The tranquil atmosphere and soft sands make it ideal for relaxation and enjoying stunning sunsets over the Gulf of Mexico.
  • Bald Point State Park: Explore the natural wonders of Bald Point State Park, where you can hike scenic trails, observe diverse wildlife, and enjoy outdoor adventures. The park offers breathtaking views of coastal marshes and opportunities for birdwatching.
  • USS Mohawk CGC Veterans Memorial Reef: Dive into history at the USS Mohawk CGC Veterans Memorial Reef. This unique artificial reef honors veterans and provides a vibrant underwater habitat for marine life, making it a fantastic spot for snorkeling and diving.

Best time to go to Panacea

The best time to visit Panacea is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are average and weather is mostly sunny. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January53.6°F (12.0°C)Light RainMostly SunnyAverageSlightly Low
February57.6°F (14.2°C)Light RainMostly SunnyAverageAverage
March62.4°F (16.9°C)Light RainMostly SunnyAverageAverage
April68.2°F (20.1°C)Light RainMostly SunnyModerately HighAverage
May74.8°F (23.8°C)Light RainMostly SunnyAverageSlightly High
June80.4°F (26.9°C)Moderate RainMostly SunnyModerately HighAverage
July81.7°F (27.6°C)Moderate RainMostly SunnyModerately HighSlightly Low
August81.7°F (27.6°C)Moderate RainMostly SunnyAverageAverage
September78.4°F (25.8°C)Light RainMostly SunnyAverageSlightly High
October71.1°F (21.7°C)Light RainMostly SunnyModerately LowSlightly High
November61.9°F (16.6°C)Light RainMostly SunnyModerately LowAverage
December57.6°F (14.2°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to Panacea

If you're planning to visit Panacea, Florida, the closest major airport is Tallahassee International Airport (TLH), situated 41.8km away. For convenient accommodations, consider staying at the DoubleTree by Hilton Hotel Tallahassee or Hotel Duval, both 8.0km from the airport and rated 4 stars. Both hotels offer transportation services to TLH, ensuring a smooth travel experience. Alternatively, the 3.5-star Hotel Indigo Tallahassee - Collegetown is just 6.4km from TLH, providing easy access as well. Each of these hotels offers comfort and accessibility for your trip to the charming town of Panacea.

Frequently asked questions

Where is the best place to stay in Panacea?
Expedia customers give high marks to The Panacea Motel. See all available top hotels, or vacation rentals in Panacea.
If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
Where can I learn more about changing or cancelling my trip to Panacea?
For more details about changing or cancelling your trip to Panacea, click here.
What's the best pet-friendly place to stay in Panacea?
The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What's the best hotel for staying near Tallahassee Regional Airport (TLH)?
Tallahassee Sun & Moon is one of the top choices for your stay and is a popular property, featuring free WiFi and free parking. It's located 3.5 mi (5.7 km) from Tallahassee Regional Airport. Other options close to the airport include Hampton Inn & Suites Tallahassee Capitol-University and Governors Inn.
What's it like to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 212 hotels and other accommodations to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Wilson Beach and Public Beach Access. Check out what more to see and do in Expedia's Panacea guide.
What's the seasonal weather like in Panacea?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.

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