Find hotels in Nuevo Santiago from NT$1,891

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Go beyond your typical stay in Nuevo Santiago

pet friendly image
Pet friendly
Pet friendly
Pool image
Pool
Pool

Check prices for these dates

Tonight
Nov 6 - Nov 7
Tomorrow
Nov 7 - Nov 8
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Nuevo Santiago hotels

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (605 reviews)
"The service is pretty stable."
United States
Yali
The price is NT$2,512
NT$2,763 total
includes taxes & fees
Nov 17 - Nov 18
Hotel Mykonos Panama
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.

2. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
3.0 star property
Nuevo Santiago
8.8 out of 10, Excellent, (15 reviews)
"The front desk gentleman was very helpful and took extra measures to see that I was taken care of. A great asset to your hotel."
United States
James
The price is NT$1,891
NT$2,080 total
includes taxes & fees
Nov 7 - Nov 8
Hotel Plaza Los Tucanes
A pool surrounded by palm trees and a tiled roof structure.

3. Hotel Gran David

Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (449 reviews)
"Great place to stay. I would stay there again."
United States
Roxani
The price is NT$2,889
NT$3,178 total
includes taxes & fees
Dec 1 - Dec 2
Hotel Gran David
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.

4. HOTEL VISTA LAGO

HOTEL VISTA LAGO
3.0 star property
La Pena
9.4 out of 10, Exceptional, (128 reviews)
"We went to this hotel for the first time and it’s so amazing, excellent food nothing else to add"
United States
Christian
The price is NT$2,512
NT$2,763 total
includes taxes & fees
Nov 8 - Nov 9
HOTEL VISTA LAGO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Nuevo Santiago

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

Hotel Mykonos Panama

3.5 star property
Nuevo Santiago
View
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.

Hotel Plaza Los Tucanes

3.0 star property
Nuevo Santiago
View
A pool surrounded by palm trees and a tiled roof structure.

Hotel Gran David

3.5 star property
Santiago
View
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.

HOTEL VISTA LAGO

3.0 star property
La Pena
View
8.8
Excellent
605 reviews
8.8
Excellent
15 reviews
8.6
Excellent
449 reviews
9.4
Exceptional
128 reviews
The price is NT$2,512
NT$2,763 total
includes taxes & fees
Nov 17 - Nov 18
The price is NT$1,891
NT$2,080 total
includes taxes & fees
Nov 7 - Nov 8
The price is NT$2,889
NT$3,178 total
includes taxes & fees
Dec 1 - Dec 2
The price is NT$2,512
NT$2,763 total
includes taxes & fees
Nov 8 - Nov 9
  • Yes, Breakfast included
  • Yes, Pool
  • Yes, Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families in Nuevo Santiago

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (605)
The price is NT$2,512
NT$2,763 total
includes taxes & fees
Nov 17 - Nov 18
Hotel Mykonos Panama

Learn more about Nuevo Santiago

Check out Parque Acuatico Italia Guadalupe Panama and Catedral of Santiago Apostol—just a couple of the sights around Nuevo Santiago.

See all hotels in Nuevo Santiago
A lush valley with dense green forests, rolling hills, and a cloudy sky.

Top Nuevo Santiago Hotel Reviews

A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
HOTEL VISTA LAGO

HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena

10/10 Excellent

Muy bueno.. solo como feedback un poquito mas de ronda cuando uno esta comiendo y alguien en la piscina por si se quiere pedir algo.. por lo demás todo muy bueno y personas muy amables... volvería!!!!
United States
Sharyn
Reviewed November 4, 2026
HOTEL VISTA LAGO

Frequently Asked Questions

If I need to cancel my hotel reservation in Nuevo Santiago, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Nuevo Santiago.

Where can I learn more about changing or cancelling my trip to Nuevo Santiago?

To access more information about changing or cancelling your trip to Nuevo Santiago, go to https://www.expedia.com/service/.

How is it staying in Nuevo Santiago?

Travelers to Nuevo Santiago will find plenty to explore and enjoy. In Nuevo Santiago, there are 4 hotels and other accommodations to choose from. Find out more about Nuevo Santiago.

What should I see while I'm in Nuevo Santiago?

Places to visit in the wider area include Parque Acuatico Italia Guadalupe Panama, Catedral of Santiago Apostol, and Los Pozos Termales. You'll also find Plaza Banconal and Omar Torrijos Herrera Stadium in the area. Check out what more to see and do in Expedia's Nuevo Santiago guide.

What's the weather like in Nuevo Santiago?

The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Nuevo Santiago are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.

Where is the best place for a stay in Nuevo Santiago?

Hotel Mykonos Panama is one of the top choices for your stay based on our traveler data. This hotel offers 3 outdoor pools and a full-service spa. Other good choices for your stay include Hotel Plaza Los Tucanes and Hotel Galería. See all available top hotels, or vacation rentals in Nuevo Santiago.