New Madrid Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to NT$25,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Find the Best New Madrid Vacation Packages
New Madrid Hotel Deals
Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Fully refundable
NT$3,133
NT$3,548 total
Aug 23 - Aug 24
includes taxes & fees
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
NT$3,202
NT$3,625 total
Aug 23 - Aug 24
includes taxes & fees
9/10 Wonderful! (607 reviews)
"Hotel was nice but unfortunately someone decided to smoke in the elevator one night which made it shut down. So, until the repair was completed, everyone one the upper floors had to take the stairs down multiple floors. Usually not that big of an issue, but we were there for a bike ride and had to ..."
Reviewed on 2026/8/10
Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
NT$3,544
NT$4,013 total
Aug 20 - Aug 21
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular New Madrid attractions
New Madrid Historical Museum
8.2/10 (36 reviews)
Explore the powerful 1811-1812 earthquakes that reshaped America's heartland at this historic museum. Engage with knowledgeable curators while viewing artifacts from Native American cultures and the Civil War.
Hunter-Dawson State Historic Site
7.6/10 (13 reviews)
Step back in time at this antebellum mansion with 80% of its original furnishings intact. Explore nine fireplaces and period decor through guided tours of the 15-room Hunter-Dawson House.
River Ridge Winery
8.4/10 (15 reviews)
Sip handcrafted wines in a century-old farmhouse atop the Mississippi River hills. Wander through estate vineyards or enjoy fresh meals on the scenic grounds of this Missouri wine destination.
Frequently asked questions
How much does a New Madrid vacation package cost?
Offering great value package deals on Expedia, you'll be thrilled with how little a vacation to New Madrid costs! Expedia's packages make travel planning easier and your savings go further.
What are the cheapest months to go to New Madrid?
To pick up cheap New Madrid vacation packages, plan your getaway outside of peak periods like public holidays and major festivals. You'll typically find lower prices and better availability in the off-season or when it's less busy.
How many days is enough for New Madrid?
Usually, a handful of days is enough to visit the top attractions during your New Madrid vacation. However, if you prefer to have time to unwind or go on day trips, think about extending your trip.
Is it worth booking a vacation package to New Madrid?
New Madrid is a good vacation destination with attractions like New Madrid Historical Museum among the many things to keep you entertained. Whether you're traveling with the family or getting away with friends, a New Madrid vacation promises a good time for everyone.
How to find the best New Madrid package deals?
Use Expedia's filters to find some unbeatable New Madrid package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or browse for New Madrid package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's usually best to book your vacation package as soon as possible.
Is it cheaper to book a New Madrid vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component individually. And you'll still have the freedom to create a customized New Madrid vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to New Madrid?
Enjoy incredible discounts by booking your flights ahead of time with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu New Madrid adventure.
How to plan a trip to New Madrid?
- Choose when to go: Check your schedule and pack your bags. Your preferred season and the available activities will also help you decide when to vacation in New Madrid.
- Calculate your budget: Ensure you have enough money to pay for everything from dining out and transportation to experiences and flights. Your accommodations will likely be the biggest expense during your trip to New Madrid.
- Decide your trip length: Think about how long you want to spend exploring New Madrid. Plan your days so you can get to all the attractions and experiences you're interested in at a comfortable pace.
- Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to choose a New Madrid vacation package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
