Mission Bay Vacations

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Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Vibrant activity in Union Square, San Francisco with palm trees and bustling city life

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Mission Bay Hotel Deals

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is NT$7,919 per night from Apr 5 to Apr 6
NT$7,919
NT$9,320 total
Apr 5 - Apr 6
includes taxes & fees
9.6/10 Exceptional! (2,432 reviews)
LUMA represents good value and a great stay. Rooms are good size, amenities fine for business traveler. The location is fun and up and coming

Reviewed on 2026/3/12

LUMA Hotel San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
The price is NT$4,190 per night from Apr 12 to Apr 13
NT$4,190
NT$4,932 total
Apr 12 - Apr 13
includes taxes & fees
9/10 Wonderful! (5,395 reviews)
I’m not sure ir I stayed in room 2322 or 2320, but the room was very clean and neat at my arrival. As someone that worked in hospitality for many years I know exactly when I room is clean. Very friendly and helpful staff starting by my housekeeper who gave me some advice to navigate around the city ...

Reviewed on 2026/3/13

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is NT$4,747 per night from Apr 1 to Apr 2
NT$4,747
NT$5,587 total
Apr 1 - Apr 2
includes taxes & fees
8.8/10 Excellent! (2,912 reviews)
Location great. Poll was being rehabbed.

Reviewed on 2026/3/13

Handlery Union Square Hotel
See all 4,898 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Bay vacation package cost?
Custom make your Mission Bay vacation package from as low as . Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay vacation package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay vacation?
Smart travelers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organizing an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia vacation package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay vacation package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay vacation package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Discover the most popular places to visit in Mission Bay

Chase Center San Francisco Skyline Aerial Photography

Chase Center

Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.

Chase Center
Oracle Park featuring a bay or harbor and street scenes as well as a small group of people

Oracle Park

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
Vibrant crowds enjoying Pier 39 with shops, dining, and views of the San Francisco Bay

Pier 39

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Pier 39
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.