Photo by Caroline Nunez

Find hotels in Mayesville, SC from NT$1,766

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Learn more about Mayesville

Venture to Riley Field and O'Donnell House—just two of the sights around Mayesville.

See all hotels in Mayesville
Somewhere in rural South Carolina off a back road to my hometown. Saw the sunflower field and had to stop.
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Mayesville Hotel Reviews

SpringHill Suites Sumter

SpringHill Suites Sumter

10/10 Excellent
"Clean, large room. Appreciate the set up and separate bathroom "
Joanne 1-night trip
Posted 2 days ago
SpringHill Suites Sumter

More cheap stays in Mayesville

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2816 Paxville Highway Manning SC
The price is NT$2,681 per night from Jan 1 to Jan 2
NT$2,681
NT$2,976 total
Jan 1 - 2026/1/2
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)

Hotels in Mayesville with star-rating

Frequently asked questions

What's the best place for a stay in Mayesville?
Tru by Hilton Sumter, located 11.1 mi (17.9 km) from the heart of Mayesville, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Woodspring Suites Sumter Near Shaw Afb and Hyatt Place Sumter / Downtown. See all available top hotels, or vacation rentals in Mayesville.
If I need to cancel my hotel reservation in Mayesville, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mayesville.
Where can I learn more about changing or cancelling my trip to Mayesville?
For more information about changing or cancelling your trip to Mayesville, head over to our customer service page.
What is the best hotel near Florence Regional Airport (FLO)?
Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an outdoor pool. It's located 2.2 mi (3.5 km) from Florence Regional Airport. Other good choices near the airport include Hotel Florence, an Ascend Hotel Collection Member and Baymont Inn & Suites Florence by Wyndham.
What is staying in Mayesville like?
Travelers to Mayesville will find plenty to explore and enjoy. There are 73 hotels and other accommodations in the surrounding area. Find out more about Mayesville.
What should I see while I'm in Mayesville?
Places to visit in the wider area include Riley Field, O'Donnell House, and Sumter Mall. You'll also find Palmetto Tennis Center and Swan Lake Iris Gardens in the area. Check out what more to see and do in Expedia's Mayesville guide.
What's the weather like in Mayesville?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Mayesville is 52 inches.

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