A marshy landscape with water, trees, and a distant city skyline.

Best Western Ladys Island hotels

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Our top choices for Ladys Island Best Western

1. Best Western Sea Island Inn

Best Western Sea Island Inn
2.5 star property
Historic District
9.6 out of 10, Exceptional, (1,001 reviews)
"Staff were welcoming and helpful"
United States
Paul
Best Western Sea Island Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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