La Serena Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for La Serena vacation rentals

Garden
Apart Hotel y Cabañas Vegasur

Aparthotel in La Serena

Apart Hotel y Cabañas Vegasur
3.0 star property
8.6 out of 10, Excellent, (93)
"LIMPIEZA BUENA, NO TENGO REPAROS AL RESPECTO."
Chile
Martin
Apart Hotel y Cabañas Vegasur
32-inch flat-screen TV with cable channels, first-run movies
Domos Dream hotel cabañas

Camping in La Serena

Domos Dream hotel cabañas
2.0 star property
8.6 out of 10, Excellent, (4)
"It was far away."
Mexico
Sergio
The price is NT$2,500
NT$2,500 total
Dec 23 - Dec 24
Domos Dream hotel cabañas
3 outdoor pools, open 11:00 AM to 8:00 PM, pool umbrellas
Cabaña Villa Los Plátanos

Cabin in La Serena

Cabaña Villa Los Plátanos
3.0 star property
10.0 out of 10, Exceptional, (2)
The price is NT$2,598
NT$2,598 total
Dec 26 - Dec 27
Cabaña Villa Los Plátanos
Honeymoon Cabin | Terrace/patio
IndomitoElqui

Cabin in Paiguano

IndomitoElqui
2.0 star property
10.0 out of 10, Exceptional, (1)
The price is NT$2,245
NT$3,285 total
Dec 23 - Dec 24
IndomitoElqui
Exterior
Oceana Suites - Laguna Aculeo

Vacation Home in Coquimbo

Oceana Suites - Laguna Aculeo
2.0 star property
The price is NT$4,734
NT$9,469 total
Jan 1 - 2026/1/2
Oceana Suites - Laguna Aculeo
15 outdoor pools, open 10:00 AM to 8:30 PM, pool umbrellas, sun loungers
Cabañas de la Costa

Cabin in La Serena

Cabañas de la Costa
3.0 star property
10.0 out of 10, Exceptional, (1)
"They were very hospitable. And I would recommend it to anybody that comes to coquimbo."
United States
Erwin
The price is NT$4,204
NT$4,204 total
Jan 1 - 2026/1/2
Cabañas de la Costa
Interior
Cabañas Yunkai

Cabin in Vicuña

Cabañas Yunkai
3.0 star property
The price is NT$2,651
NT$2,651 total
Dec 25 - Dec 26
Cabañas Yunkai
Exterior
Parcela Los Nonos

Cabin in Vicuña

Parcela Los Nonos
3.0 star property
Parcela Los Nonos
Apartment, Patio, Garden View | Terrace/patio
Yunkai Home

Apartment in Vicuña

Yunkai Home
2.0 star property
The price is NT$3,118
NT$3,118 total
Dec 23 - Dec 24
Yunkai Home
In-room safe, free WiFi, bed sheets
ELDEPTO LA SERENA

Apartment in Coquimbo

ELDEPTO LA SERENA
3.0 star property
6.0 out of 10, (1)
ELDEPTO LA SERENA
Classic Apartment, Ocean View | Living area
Depto Serena Golf

Apartment in La Serena

Depto Serena Golf
2.0 star property
The price is NT$7,276
NT$9,355 total
Dec 23 - Dec 24
Depto Serena Golf
Restaurant
Club Playa Blanca

Aparthotel in Coquimbo

Club Playa Blanca
2.5 star property
6.0 out of 10, (2)
"The view was amazing. Property was well kept."
United States
claudia
Club Playa Blanca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top La Serena Hotel Reviews

Hotel Diego de Almagro La Serena Express

Hotel Diego de Almagro La Serena Express

10/10 Excellent
"Great property with lots of amenities. Only thing that l missed was an iron for my shirts. Other than that l give it a 10"
Cesar 2-night trip
Posted 3 weeks ago
Hotel Diego de Almagro La Serena Express

Find out more about La Serena

Search for holiday rentals in La Serena on Expedia! You can easily find your home rentals, villas, holiday apartments in La Serena using one of the methods below:

  • View our selection of featured holiday rentals in La Serena
  • Use the map to find apartments and other holiday homes in the La Serena neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Serena while they last

Look no further and take a look at our great range of rental properties in La Serena!

Frequently asked questions

Can I find a vacation rental in La Serena?

Yes, we give you a choice of vacation rentals in La Serena near Jardin del Corazon, or you can go with a more remote option if you're looking for a relaxing stay. La Serena is known for its sightseeing tours and spas. Make sure you have time to check out the casinos while you're in the area.

How many vacation rentals will I find in La Serena?

With 17 Expedia vacation rentals, you're sure to find just the right place for your La Serena stay.

What can I see and do in La Serena?

Cultural attractions include President Gabriel González Videla Regional History Museum and Casa Gabriel Gonzalez Videla Historical Museum, whereas Kokoro No Niwa Japanese Garden and La Serena Beach are a couple of picturesque spots to enjoy the outdoors. While here, Mall Plaza La Serena and La Serena Lighthouse are other places worth a visit.

What are vacation rentals like in La Serena?

Vacation rentals are private accommodations you can reserve for a short or long stay in La Serena. Vacation rentals provide amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for a family trip.