Find hotels in La Mesa from NT$1,653

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Dec 5 - Dec 6
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Dec 6 - Dec 7
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Compare 445 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Outdoor pool, pool umbrellas, sun loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4.0 star property
Tocumen
8.4 out of 10, Very Good, (2325)
"The room was clean and the staff were nice! "
United States
CECILIA
The price is NT$3,444
NT$3,788 total
includes taxes & fees
Dec 24 - Dec 25
Crowne Plaza Panama Airport by IHG
Living area
ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport

2.0 star property
Tocumen
9.0 out of 10, Wonderful, (32)
"Very nice boutique hotel"
United States
Fernando
The price is NT$3,757
NT$4,133 total
includes taxes & fees
Dec 6 - Dec 7
ORHO HOTEL BOUTIQUE PANAMA Airport
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4.0 star property
Tocumen
8.6 out of 10, Excellent, (1856)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is NT$3,915
NT$4,307 total
includes taxes & fees
Dec 8 - Dec 9
Riande Aeropuerto Hotel & Casino
Suite, 1 Bedroom, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (635)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is NT$7,256
NT$7,981 total
includes taxes & fees
Dec 19 - Dec 20
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Laptop workspace, soundproofing, free WiFi, bed sheets
B&B Lodgings

B&B Lodgings

2.5 star property
24 de Diciembre
7.8 out of 10, Good, (70)
"I givethis rating of five stars because Daisy the owner, is so wonderful. I ended up checking in late. She helped me order food. She was very very accommodating. Her English is very good. The room that I stayed in was very clean and had everything that you would need. I will stay there again When I will have to stay in Panama City. The grounds are absolutely beautiful."
United States
Stephanie
The price is NT$1,503
NT$1,653 total
includes taxes & fees
Jan 3 - 2026/1/4
B&B Lodgings
Outdoor pool, pool umbrellas, sun loungers
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1114)
"Property and location was excellent. Staff is very accommodating and helpful. "
Canada
Helen
The price is NT$3,134
NT$3,447 total
includes taxes & fees
Jan 2 - 2026/1/3
Ramada Plaza by Wyndham Panama Punta Pacifica
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1002)
"Conveniently located near the airport and major shopping outlets."
United States
Greg
The price is NT$3,168
NT$3,484 total
includes taxes & fees
Jan 5 - 2026/1/6
Courtyard by Marriott Panama Metromall
50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (150)
"Wonderful place great staff "
United States
Shantia
The price is NT$1,942
NT$3,583 total
includes taxes & fees
Dec 15 - Dec 16
Arcadia Condo Suites
Terrace/patio
Sheraton Grand Panama

Sheraton Grand Panama

4.0 star property
San Francisco
8.6 out of 10, Excellent, (988)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is NT$4,227
NT$4,649 total
includes taxes & fees
Dec 18 - Dec 19
Sheraton Grand Panama
Outdoor pool, pool umbrellas, sun loungers
The Westin Panama

The Westin Panama

4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (307)
"Hotel was great and the staff was amazing "
United States
FREDRICK L.
The price is NT$5,629
NT$6,192 total
includes taxes & fees
Dec 24 - Dec 25
The Westin Panama
Apartment, 1 Bedroom, Balcony | Property grounds
Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen

2.0 star property
Las Mañanitas
The price is NT$2,370
NT$2,971 total
includes taxes & fees
Dec 10 - Dec 11
Swette Love 10 Minutes From the Airport Tocumen
Exterior
Aloft Panama

Aloft Panama

3.5 star property
San Francisco
8.8 out of 10, Excellent, (889)
"The staff was very friendly, rooms were clean and modern."
United States
Greg
The price is NT$3,663
NT$4,029 total
includes taxes & fees
Dec 21 - Dec 22
Aloft Panama
Outdoor pool
Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar

3.5 star property
San Francisco
7.6 out of 10, Good, (151)
"Clean room good place to stay "
United States
Gideon
The price is NT$1,562
NT$6,108 total
includes taxes & fees
Dec 6 - Dec 7
Boutique Apartments Panamá Coco del Mar
Lobby sitting area
San Francisco by Wynwood House

San Francisco by Wynwood House

3.0 star property
San Francisco
9.2 out of 10, Wonderful, (54)
"This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! "
United States
mario
The price is NT$4,537
NT$5,773 total
includes taxes & fees
Dec 7 - Dec 8
San Francisco by Wynwood House
Outdoor pool
Boutique Apartments Atlapa

Boutique Apartments Atlapa

3.0 star property
San Francisco
7.8 out of 10, Good, (25)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa
Outdoor pool
Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments

3.0 star property
San Francisco
The price is NT$1,299
NT$6,031 total
includes taxes & fees
Dec 22 - Dec 23
Living 73 Panamá by Boutique Apartments
Apartment | Internet
w Bright 1BR w Private Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
San Francisco
The price is NT$2,868
NT$4,084 total
includes taxes & fees
Dec 7 - Dec 8
w Bright 1BR w Private Balcony in San Francisco
Front of property
Express Inn Panama International Airport Hostel

Express Inn Panama International Airport Hostel

1.5 star property
Tocumen
6.0 out of 10, (653)
"Perfect for a quick overnight before a flight out of PTY or a land and rest location. "
United States
Cecily
The price is NT$1,550
NT$1,705 total
includes taxes & fees
Dec 6 - Dec 7
Express Inn Panama International Airport Hostel
Apartment, 3 Bedrooms, Accessible, Pool View | Children's area
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City

2.0 star property
José Domingo Espinar
The price is NT$2,231
NT$2,454 total
includes taxes & fees
Dec 7 - Dec 8
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Apartment | 1 bedroom
Elegant 1BR Near Multiplaza

Elegant 1BR Near Multiplaza

2.0 star property
San Francisco
The price is NT$6,116
NT$6,727 total
includes taxes & fees
Dec 6 - Dec 7
Elegant 1BR Near Multiplaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

10/10 Excellent
"As usual the stay was amazing in this hotel"
Jose 2-night trip
Posted 2 days ago
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

More cheap stays in La Mesa

Arcadia Condo Suites

Arcadia Condo Suites

Calle rio mar Panama City Panamá Province
The price is NT$1,942 per night from Dec 15 to Dec 16
NT$1,942
NT$3,583 total
Dec 15 - Dec 16
includes taxes & fees
9.4/10 Exceptional! (150 reviews)

Frequently asked questions

Where is the best place to stay in La Mesa?
Crowne Plaza Panama Airport by IHG, located 9.9 mi (15.9 km) from the heart of La Mesa, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Sheraton Grand Panama and Arcadia Condo Suites. See all available top hotels, or vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
Where can I learn more about changing or cancelling my trip to La Mesa?
To access more information about updating your trip to La Mesa or cancelling it, go to https://www.expedia.com/service/.
What is staying in La Mesa like?
Visitors to La Mesa are sure to find plenty to explore and enjoy. There are 386 hotels and other accommodations in the surrounding area. Find out more about La Mesa.
What are the top places to visit in La Mesa?
Places to visit in the wider area include Metromall Panama, Los Pueblos Commercial Center, and Estadio Rommel Fernandez. You'll also find Chagres National Park and Chepo Youth Recreation Center in the area. Check out what more to see and do in Expedia's La Mesa guide.
What's the weather like in La Mesa?
The hottest months are usually April and March with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in La Mesa are July, August, October, and June, with each month seeing an average of 14 inches of rainfall.

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