A calm lake surrounded by trees with autumn foliage.

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Nov 6 - Nov 8
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Nov 13 - Nov 15

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Our top choices for Florence, SC (FLO-Florence Regional) hotels

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (2,747 reviews)
"Quiet clean and inexpensive stay, especially relative to neighboring locations"
United States
Carl
The price is NT$1,981
NT$2,219 total
includes taxes & fees
Nov 5 - Nov 6
Howard Johnson by Wyndham Florence
A hotel lobby with a reception desk, seating area, and a television screen.

2. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,387 reviews)
"Comfortable beds and clean environments."
United States
Steven
The price is NT$3,296
NT$3,691 total
includes taxes & fees
Nov 24 - Nov 25
Comfort Inn & Suites Florence Center Area
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

3. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (2,499 reviews)
"Great place to spend the night during our road trip. Would stay again."
United States
Susan
The price is NT$2,941
NT$3,293 total
includes taxes & fees
Nov 15 - Nov 16
Park Inn by Radisson Florence, SC
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

4. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,004 reviews)
"Good location, clean room and good breakfast."
United States
NOORUDIN
The price is NT$3,711
NT$4,157 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn & Suites Florence Center
A hotel entrance with a covered walkway, columns, and a number '340' sign.

5. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,000 reviews)
"Wonderful hotel and in a great location!"
United States
Leigh
The price is NT$3,714
NT$4,160 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel entrance with a stone facade, glass doors, and a number '501' above.

6. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (664 reviews)
"I enjoyed a two night stay here at Fairfield. The staff was completely awesome. The breakfast was amazing, so many options to choose from to meet every healthy meal plan. The amenities were very clean, modern and chic, providing an upscale experience. Overall experience was excellent!"
United States
Alma
The price is NT$3,850
NT$4,312 total
includes taxes & fees
Nov 11 - Nov 12
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

7. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (923 reviews)
"Fabulous pet-friendly place to stay."
United States
Ralph
The price is NT$3,573
NT$4,001 total
includes taxes & fees
Nov 5 - Nov 6
TownePlace Suites by Marriott Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

8. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
8.4 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,001 reviews)
"Great hotel and staff"
United States
Margarita
The price is NT$2,963
NT$3,513 total
includes taxes & fees
Nov 15 - Nov 16
Tru by Hilton Florence I-95
A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

9. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.4 out of 10, Exceptional, (1,003 reviews)
"Enjoyed our stay."
United States
Tishia
The price is NT$4,429
NT$4,960 total
includes taxes & fees
Nov 8 - Nov 9
Staybridge Suites Florence - Civic Center by IHG
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

10. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (348 reviews)
"Great staff easy Check in I love staying here!!!"
United States
Alanya
The price is NT$3,157
NT$3,730 total
includes taxes & fees
Nov 10 - Nov 11
Spark by Hilton Florence North I-95, SC
A modern lounge area with brick walls, large windows, and contemporary furniture.

11. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
3.5 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,008 reviews)
"Great breakfast. Check-in and check-out was very easy."
United States
Jonathan
The price is NT$4,203
NT$4,708 total
includes taxes & fees
Nov 5 - Nov 6
Hyatt Place Florence Downtown
A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

12. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
10.2 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (419 reviews)
"Nice spot for an overnight!"
United States
Sharhonda
The price is NT$2,903
NT$3,252 total
includes taxes & fees
Nov 10 - Nov 11
Quality Inn & Suites Florence Civic Center
A spacious lobby with a reception desk, seating area, and large windows.

13. Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (361 reviews)
"Rooms were clean and staff was friendly."
United States
Derrick
The price is NT$3,711
NT$4,157 total
includes taxes & fees
Nov 15 - Nov 16
Hilton Garden Inn Florence
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

14. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
8.2 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,002 reviews)
"Excellente hotel, clean, good breakfast, and quiet."
Canada
chantal
The price is NT$3,988
NT$4,467 total
includes taxes & fees
Nov 10 - Nov 11
Hampton Inn & Suites Florence-North-I-95
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

15. Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (587 reviews)
"The room was clean and spacious. The staff was friendly."
United States
Teri
The price is NT$3,493
NT$3,912 total
includes taxes & fees
Nov 8 - Nov 9
Residence Inn Marriott Florence
Terrace/patio

16. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
3.0 star property
10.4 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (1,001 reviews)
"Great for families"
United States
saleh
The price is NT$3,711
NT$4,350 total
includes taxes & fees
Nov 15 - Nov 16
Home2 Suites by Hilton Florence, SC
A Holiday Inn Express & Suites hotel with a covered entrance, multiple windows, and a parking lot.

17. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,000 reviews)
"Good location- very good free breakfast"
United States
Christopher
The price is NT$3,975
NT$4,775 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.

18. Affordable Suites Florence

Affordable Suites Florence
2.5 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (232 reviews)
"Location is awesome and near everything the staff are very friendly and kind will definitely be coming back for more hotel stays"
United States
Cheyenne
The price is NT$2,346
NT$2,628 total
includes taxes & fees
Nov 5 - Nov 6
Affordable Suites Florence
A multi-story hotel with a prominent entrance and signage for Springhill Suites by Marriott.

19. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
9.8 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very good, (1,002 reviews)
"Staff is so helpful hotel is very clean well kept"
United States
Tom
The price is NT$3,343
NT$3,938 total
includes taxes & fees
Nov 8 - Nov 9
SpringHill Suites by Marriott Florence
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

20. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very good, (1,001 reviews)
"Our room was very clean and quiet. The staff was excellent and the breakfast was very good. They did charge us a $5.95 fee for the use of the amenities, gym, pool and breakfast located at the property."
United States
Michael
The price is NT$3,354
NT$4,081 total
includes taxes & fees
Dec 1 - Dec 2
Comfort Suites Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Florence, SC (FLO-Florence Regional)

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
Howard Johnson by Wyndham Florence
2.0 star property
8.6
Excellent
2,747 reviews
View
A hotel lobby with a reception desk, seating area, and a television screen.
Comfort Inn & Suites Florence Center Area
2.5 star property
9.0
Wonderful
1,387 reviews
View
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
Park Inn by Radisson Florence, SC
2.5 star property
9.0
Wonderful
2,499 reviews
View
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
Hampton Inn & Suites Florence Center
2.5 star property
9.0
Wonderful
1,004 reviews
View
A hotel entrance with a covered walkway, columns, and a number '340' sign.
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
9.0
Wonderful
1,000 reviews
View

Top Florence Regional Hotel Reviews

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

10/10 Excellent
"Rooms were clean, the staff were really kind, the breakfast had some variety. Would stay again if I needed to go to Florence, South Carolina. Very walkable, in the downtown area."
Chelsea 2-night trip
Posted 7 hours ago
Hyatt Place Florence Downtown

Guide to exploring around Florence Regional

Florence Regional hotels information

Number of reviews
9,924
Accommodation
133 hotels
Lowest Price
NT$2,219
Highest Price
NT$4,960

Frequently asked questions

What's the area like near Florence, SC (FLO-Florence Regional)?

Florence, SC (FLO-Florence Regional) is located in a welcoming area of Florence known for its array of dining options. You'll find 72 hotels and other accommodations within a few miles of the airport for a convenient home base.

What's the best place to stay close to Florence, SC (FLO-Florence Regional)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.2 mi (3.5 km) from Florence, SC (FLO-Florence Regional). Other good choices near the airport include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels will I find close to Florence, SC (FLO-Florence Regional)?

Expedia has 72 hotels and other accommodations a few miles from the airport.

What can I see and do near the airport in Florence?

Sights like Mcleod Regional Medical Center and Florence Stockade highlight some of the local culture. You can enjoy live performances at Florence Little Theatre and FMU Performing Arts Center. If you've got some time to explore the area around Florence, SC (FLO-Florence Regional), you may want to make a stop by Dr. Eddie Floyd Tennis Center, Southgate Bowling Center, and CarolinaBank Field.