Find Luxury Hotels in Florence, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Florence Luxury Hotels

Tonight
Feb 5 - Feb 6
Tomorrow
Feb 6 - Feb 7
This weekend
Feb 6 - Feb 8
Next weekend
Feb 13 - Feb 15
No exact matches found, but these alternatives could be just right

Recommended hotels in Florence

Exterior

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (955 reviews)
"Room clean, bed good, breakfast good choices, front desk excellent"
United States
mona
The price is NT$4,256
NT$4,767 total
includes taxes & fees
Feb 8 - Feb 9
Staybridge Suites Florence - Civic Center by IHG
Exterior

The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (852 reviews)
"We always enjoy our stay at the Inn. Food at the Bistro never disappoints and the bartender is always friendly and remembers us from past visits. "
United States
Barbara
The price is NT$4,114
NT$4,608 total
includes taxes & fees
Feb 8 - Feb 9
The Inn at the Crossroads
Exterior

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,003 reviews)
"Friendly staff, quick check in, nice lobby"
United States
Jennifer
The price is NT$3,851
NT$4,313 total
includes taxes & fees
Mar 8 - Mar 9
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Hotel Reviews

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

10/10 Excellent
"Great room and reasonable price "
Hattab 1-night trip
Posted 4 days ago
Days Inn by Wyndham Florence/I-95 North
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

10/10 Excellent
"This was best Quality Inn that I ever stayed in the room was clean new furniture and new bathroom. The bathroom had new tile and shower and everything was very clean and the staff was great "
Shannon 1-night trip
Posted 9 days ago
Quality Inn & Suites Florence Civic Center

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you'd like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Dr. Eddie Floyd Tennis Center. If you have extra time while you're in the area, you might want to stop by Magnolia Mall and Florence Civic Center.
How can I get around Florence?
It's easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.

Explore a world of travel with Expedia