Find Luxury Hotels in Florence, SC

Check availability on Florence Luxury Hotels

Tonight
Aug 4 - Aug 5
Tomorrow
Aug 5 - Aug 6
This weekend
Aug 8 - Aug 10
Next weekend
Aug 15 - Aug 17

Top Florence Luxury Hotels

The Mantissa Hotel
Rooftop terrace

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (248)
"I love the stay it was amazing. This place did not disappoint."
The Mantissa Hotel
Days Inn by Wyndham Dillon
Exterior

Days Inn by Wyndham Dillon

2.0 star property
5.4 out of 10, (817)
"Nice for last minute get away."
Days Inn by Wyndham Dillon
Hotel Florence, Tapestry Collection by Hilton
Bar (on property)

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (577)
"Really nice, really pretty, friendly staff , lovely stay "
Hotel Florence, Tapestry Collection by Hilton
Days Inn by Wyndham Florence/I-95 North
Free daily on-the-go breakfast

Days Inn by Wyndham Florence/I-95 North

2.0 star property
6.8 out of 10, (1006)
"Nice and clean..comfy beds"
Days Inn by Wyndham Florence/I-95 North
Baymont Inn & Suites Florence by Wyndham
Breakfast area

Baymont Inn & Suites Florence by Wyndham

2.5 star property
5.6 out of 10, (1000)
"good to stay "
Baymont Inn & Suites Florence by Wyndham
Clarion Inn & Suites
Lobby

Clarion Inn & Suites

2.5 star property
4.4 out of 10, (274)
"Breakfast is a joke"
Clarion Inn & Suites
Red Roof Inn Florence - Civic Center
1 bedroom, desk, laptop workspace, free cribs/infant beds

Red Roof Inn Florence - Civic Center

2.0 star property
6.8 out of 10, (1006)
"The room was nice and clean "
Red Roof Inn Florence - Civic Center
Days Inn by Wyndham Florence Near Civic Center
Desk, iron/ironing board, free WiFi, bed sheets

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.8 out of 10, (1006)
"Good quality hotel with affordable pricing."
Days Inn by Wyndham Florence Near Civic Center
Quality Inn & Suites
Standard Room, 1 King Bed with Sofa bed, Non Smoking | Desk, iron/ironing board, rollaway beds, free WiFi

Quality Inn & Suites

2.5 star property
7.2 out of 10, Good, (716)
"Good location off I-95"
Quality Inn & Suites
Quality Inn & Suites Florence Civic Center
Premium bedding, in-room safe, desk, iron/ironing board

Quality Inn & Suites Florence Civic Center

2.5 star property
7.8 out of 10, Good, (1230)
"Great pool, breakfast and rooms. "
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Florence Hotel Reviews

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

10/10 Excellent
"it was everything i expect in a hotel. Comfortable, quiet,safe,parking, free breakfast and great staff."
oksana 1-night trip
Posted 5 days ago
Quality Inn & Suites Florence Civic Center

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you'd like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
How many luxury hotels will I be able to find in Florence?
Lie in the lap of luxury during your getaway to Florence in one of Expedia's 20 luxury hotels.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you're in the area, you might want to stop by Florence Veterans Park and Florence Civic Center.
How can I get around Florence?
It's easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.