Well, they have about a 2-hour window to check in, from 3 to 4:30, and to check out, from about 8:30 to 10:30, but if you can work that into your travels, the room was super comfortable, and actually had working air-conditioning, unlike the other 3 and 4 star hotels I booked during our Italian trip. On a busy street, but good soundproofing. As others have mentioned, the elevator is tiny, and can only fit one person with luggage at a time (not easily).
If you can put up with the quirky check in and checkout, and the elevator, you can get a great room for a great price in a great location. Breakfast is OK.