Eastern South Dakota Vacations

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Where to stay in Eastern South Dakota

Find the best Eastern South Dakota areas and neighborhoods for the activities you enjoy most. Learn more about Eastern South Dakota
These falls are right in town surrounded by a nice park.

Downtown Sioux Falls

1 out of top 10 points of interest in this area
4.5/5(108 area reviews)

While visiting Downtown Sioux Falls, you might make a stop by sights like Washington Pavilion of Arts and Science and Old Courthouse Museum.

Find hotels in Downtown Sioux Falls

Find the Best Eastern South Dakota Vacation Packages

Eastern South Dakota Hotel Deals

Hotel On Phillips

Hotel On Phillips

2.5 out of 5
100 N Phillips Ave Sioux Falls SD
Fully refundableReserve now, pay when you stay
9.4/10 Exceptional! (1,356 reviews)
Great stay. Good room. Great location

Reviewed on 2026/2/16

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Hotel On Phillips
Days Inn by Wyndham Sioux Falls Empire

Days Inn by Wyndham Sioux Falls Empire

2 out of 5
3401 Gateway Blvd Sioux Falls SD
Fully refundableReserve now, pay when you stay
The price is NT$1,728 per night from Feb 22 to Feb 23
NT$1,728
NT$1,959 total
Feb 22 - Feb 23
includes taxes & fees
7.8/10 Good! (1,086 reviews)
Very well run.Very professional, Great!

Reviewed on 2026/2/15

Days Inn by Wyndham Sioux Falls Empire
La Quinta Inn & Suites by Wyndham Sioux Falls

La Quinta Inn & Suites by Wyndham Sioux Falls

3 out of 5
4521 W. 41st Street Sioux Falls SD
Fully refundableReserve now, pay when you stay
The price is NT$2,613 per night from Feb 22 to Feb 23
NT$2,613
NT$2,929 total
Feb 22 - Feb 23
includes taxes & fees
9/10 Wonderful! (1,555 reviews)
Everything was amazing! Staff was very nice! Breakfast was delicious! Rooms were clean. The walls are kind of thin & you can hear everything but I definitely recommend staying!!

Reviewed on 2026/2/17

La Quinta Inn & Suites by Wyndham Sioux Falls
See all 961 properties in Eastern South Dakota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Eastern South Dakota

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Corn Palace

4/5(163 reviews)

After visiting Corn Palace, make a plan to see the other sights and activities in Mitchell. While in this family-friendly area, you can savor the top-notch restaurants.

Corn Palace
Aerial View of a large University in Brookings, South Dakota

South Dakota State University

4.5/5(93 reviews)

Enjoy the collegiate vibe when you visit South Dakota State University, during your trip to Brookings. Experience the area's museums and live music.

South Dakota State University
A Theremin!

University of South Dakota

4.5/5(43 reviews)

Explore the campus of University of South Dakota, during your trip to Vermillion. While in this family-friendly area, you can savor the bars and restaurants.

University of South Dakota

Frequently asked questions

Can I cancel my flight booking to Eastern South Dakota due to COVID-19?
Check out our Customer Service Portal for important details about changing or canceling flights due to COVID-19. Make sure you also check the terms and conditions of your preferred airline before booking your fare to Eastern South Dakota.
What's the best way to find cheap flights to Eastern South Dakota that have flexible change policies?
At Expedia, we've been channeling our inner Olympic gymnast to provide you with the most flexible fares on the market. Simply tick the "No change fee" box right under the "Flexible change policies" subheading to find your dream flight to Eastern South Dakota.
What are some of the general tips for travelers to Eastern South Dakota during the COVID-19 outbreak?
With new safety guidelines to follow, travel looks a little different right now. Here are a few things to know before you jet off to Eastern South Dakota:
  • Before you lock in a flight, find out if any travel restrictions apply — in both your destination and origin. Get the latest updates by checking government and travel websites.
  • Requirements state you must wear a face mask throughout your travel experience, including at security checkpoints. You should be prepared to adjust your mask for ID purposes when asked by a TSA employee.
  • Do not hand your boarding pass (electronic or paper) directly to a TSA officer. Rather, you should place the pass on the scanner and then hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your carry-on bag. You'll have to remove it for screening.
  • To minimize handling during screening, place items such as your wallet, phone and belt into your carry-on instead of the bins.
  • If you want to take food through security screening, put it in a clear plastic bag and then into a screening bin. This reduces the likelihood that a TSA agent will need to touch your food container or carry-on bag for inspection.

Which airlines fly to Eastern South Dakota?
Delta is a renowned air carrier servicing Eastern South Dakota. Look up airfares to Sioux Falls Regional Airport (FSD) and you'll have 182 Delta flights per month to select from.
How can I find cheap tickets to Eastern South Dakota?
To pick up an awesome deal to Eastern South Dakota, book ahead of time. Also think about using Expedia's "flexible dates" link above your search results. This will display prices for the days around your travel dates. In the last seven days, was the lowest price for a flight to Eastern South Dakota.
How much is a flight to Eastern South Dakota?
If you were jetting one way from (), you could've picked up a cheap fare for in the last seven days. Return flights to Eastern South Dakota ranged from only to during this same period.
What are the most popular airports to fly into in Eastern South Dakota?
Book your flight to Sioux Falls Regional Airport (FSD) and sample everything that Eastern South Dakota has to offer. As the region's main point of entry, roughly 803 flights touch down here every month.
When is the cheapest time to fly to Eastern South Dakota?
Fly out on a Tuesday to increase your chances of scoring the cheapest fare to Eastern South Dakota. Mondays are usually the next most affordable day to depart. Saturday is generally the priciest day to fly anywhere.
How much is a plane ticket to Eastern South Dakota?
In the last seven days, seats ranged between and . Check out our amazing deals to Eastern South Dakota, pick your favorite and get ready for your next fun vacation!
Which airlines with flights to Eastern South Dakota employ COVID-19 cleanliness policies?
To minimize contact between travelers and cabin crew during the ongoing pandemic, airlines have taken social distancing and other measures to the skies. A good example of these are:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.