Find hotels in Downtown Santiago, Santiago

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Downtown Santiago hotels

Hotel Sommelier Boutique

Hotel Sommelier Boutique
3.5 star property
Downtown Santiago
9.0 out of 10, Wonderful, (668)
"Excellent location and the staff was helpful. Good food in both restaurants."
United States
margarita
Hotel Sommelier Boutique

Hotel Cumbres Lastarria

Hotel Cumbres Lastarria
4.0 star property
Downtown Santiago
9.6 out of 10, Exceptional, (920)
"Nice location, friendly staff and close to major sights and restaurants. We had a wonderful stay."
United States
Xinping
The price is NT$5,677
NT$5,677 total
Jan 11 - 2026/1/12
Hotel Cumbres Lastarria

Nest Paris-Londres

Nest Paris-Londres
3.0 star property
Downtown Santiago
10.0 out of 10, Exceptional, (7)
"Beautiful and modern studio in a great location. We enjoyed our stay very much and recommend it to everyone "
United States
Mohammed
The price is NT$1,655
NT$1,655 total
Dec 24 - Dec 25
Nest Paris-Londres

LOFT Hotel by Sommelier Hoteles

LOFT Hotel by Sommelier Hoteles
3.0 star property
Downtown Santiago
9.0 out of 10, Wonderful, (195)
"Great service, clean rooms, perfect location. "
United States
Ivelina
LOFT Hotel by Sommelier Hoteles

Hotel Casa Zañartu

Hotel Casa Zañartu
4.0 star property
Downtown Santiago
8.6 out of 10, Excellent, (263)
"Very friendly staff, excellent location. Continental breakfast was very filling and restaurant food was very good."
United States
Glen C
Hotel Casa Zañartu

Casa Bueras Boutique Hotel

Casa Bueras Boutique Hotel
4.5 star property
Downtown Santiago
9.2 out of 10, Wonderful, (511)
"The staff were all so incredibly nice!!! The hotel was beautiful too!!"
United States
Kimberly
The price is NT$4,290
NT$4,290 total
Jan 17 - 2026/1/18
Casa Bueras Boutique Hotel

The Singular Santiago

The Singular Santiago
5.0 star property
Downtown Santiago
9.6 out of 10, Exceptional, (680)
"The staff were wonderful and did a great job."
United States
Muthukumarappan
The price is NT$7,254
NT$7,254 total
Dec 24 - Dec 25
The Singular Santiago

Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones
4.0 star property
Downtown Santiago
8.2 out of 10, Very Good, (622)
"Great breakfast, friendly staff, excellent location."
Canada
Petrus
The price is NT$2,586
NT$2,586 total
Dec 24 - Dec 25
Almacruz Hotel y Centro de Convenciones

Hostal Rio Amazonas

Hostal Rio Amazonas
3.0 star property
Downtown Santiago
9.4 out of 10, Exceptional, (86)
"Friendly staff, great location. Rooms simple but clean and comfortable"
Australia
anna
The price is NT$1,902
NT$1,902 total
Dec 31 - 2026/1/1
Hostal Rio Amazonas

Lastarria Hotel

Lastarria Hotel
3.0 star property
Downtown Santiago
8.8 out of 10, Excellent, (39)
"Great hotel! Very centric, clean and comfortable room and great service and staff. Next door restaurant offered breakfast for hotel guests, the staff was super friendly and accommodating and breakfast and coffee were good. Would stay again and recommend. "
United States
ileana
The price is NT$3,378
NT$3,378 total
Jan 22 - 2026/1/23
Lastarria Hotel

Lastarria Hotel & Aparts

Lastarria Hotel & Aparts
3.0 star property
Downtown Santiago
9.2 out of 10, Wonderful, (270)
"Great location, clean, well serviced and all amenities in good condition. Very helpful staff and easy check in and check out."
Australia
John
The price is NT$1,778
NT$1,778 total
Dec 24 - Dec 25
Lastarria Hotel & Aparts

Hotel Gran Palace

Hotel Gran Palace
4.0 star property
Downtown Santiago
8.2 out of 10, Very Good, (137)
"Nice staff, room was clean but showing its age. Vinyl flooring has been installed but they did a terrible job and degraded the room. Bathtub was a plus for this weary traveler."
United States
Roxanne
The price is NT$2,334
NT$2,334 total
Jan 16 - 2026/1/17
Hotel Gran Palace

Hotel Casa Aure

Hotel Casa Aure
3.0 star property
Downtown Santiago
9.0 out of 10, Wonderful, (79)
"Great location, friendly staff"
United States
Katherine
Hotel Casa Aure

Hotel Boutique Casa Conde

Hotel Boutique Casa Conde
3.5 star property
Downtown Santiago
9.8 out of 10, Exceptional, (154)
"The staff is very friendly! "
Canada
Christina
The price is NT$3,236
NT$3,236 total
Jan 2 - 2026/1/3
Hotel Boutique Casa Conde

Hotel Plaza San Francisco

Hotel Plaza San Francisco
4.0 star property
Downtown Santiago
9.2 out of 10, Wonderful, (977)
"Location beautiful hotel lovely friendly staff Close to everything "
Canada
stan
The price is NT$4,664
NT$4,664 total
Dec 24 - Dec 25
Hotel Plaza San Francisco

Altiplanico Bellas Artes

Altiplanico Bellas Artes
3.5 star property
Downtown Santiago
9.2 out of 10, Wonderful, (556)
"Great location for the centre and nearby dining establishment's "
United Kingdom
Kathleen
Altiplanico Bellas Artes

Luciano K Hotel

Luciano K Hotel
4.5 star property
Downtown Santiago
9.0 out of 10, Wonderful, (686)
"Rooms were very clean, and the staff was always willing to be helpful."
United States
Patty
The price is NT$3,987
NT$3,987 total
Jan 14 - 2026/1/15
Luciano K Hotel

Matildas Hotel Boutique

Matildas Hotel Boutique
3.5 star property
Downtown Santiago
9.4 out of 10, Exceptional, (277)
"Wonderful, memorably experience in the beautiful boutique hotel! Highly recommend. "
Canada
Emily
The price is NT$4,150
NT$4,150 total
Dec 24 - Dec 25
Matildas Hotel Boutique

Mercure Santiago Centro

Mercure Santiago Centro
3.5 star property
Downtown Santiago
8.4 out of 10, Very Good, (1002)
"Very central location. Most city landmarks at walking distance. Friendly staff."
United Kingdom
Eduardo
The price is NT$2,961
NT$2,961 total
Jan 16 - 2026/1/17
Mercure Santiago Centro

Park Plaza Apart Hotel

Park Plaza Apart Hotel
3.0 star property
Downtown Santiago
8.4 out of 10, Very Good, (645)
"It was a very comfortable stay fir my first overnight stay in Santiago. "
Canada
Paul
Park Plaza Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown Santiago

Find the best Downtown Santiago areas and neighborhoods for the activities you enjoy most.

Providencia

Boasting high-rise apartments and elegant houses, this area offers access to Cerro San Cristóbal with its Virgin Mary statue, Metropolitan Zoo, and the Teleférico. Explore the nearby bohemian Barrio Bellavista, home to artists and performers.

Las Condes

Cafes, shopping, and mountain views highlight some notable features of Las Condes. Make a stop by Alto Las Condes or KidZania Santiago while you're visiting, and jump aboard the metro at Hernando de Magallanes Station or Manquehue Station to get around town.

Vitacura

Boasting Santiago's most exclusive shopping street, Avenida Alonso de Córdova, with luxury boutiques like Louis Vuitton and Armani, this upscale area is also home to elite private schools and the Gliders Club. Easily accessible via Costanera Norte toll-way.

Lastarria

Visit this central Santiago neighborhood to relax on the lawns of Forest Park, eat in one of its many restaurants and browse weekend antique fairs.

El Golf

You might take some time to check out the abundant dining options in El Golf. Spend some time visiting top spots like Apoquindo, and catch the metro at El Golf Station or Alcantara Station to see more of the area.

Top Downtown Santiago Hotel Reviews

Frequently asked questions

What is Downtown Santiago like?
Downtown Santiago is a neighborhood that travelers like for its cathedral, museums, and art scene. Be sure to check out Fantasilandia and Palacio de la Moneda as part of your Downtown Santiago travel plans.
Where is the best place to stay in Downtown Santiago?
Based on Expedia customer reviews, Hotel Boutique Casa Conde is the highest ranked property in Downtown Santiago. This hotel offers free WiFi and concierge services. Other top choices in the neighborhood include Hotel Cumbres Lastarria and Hostel Boutique Merced 88.
How many hotels will I be able to find in the Downtown Santiago area?
Expedia has 998 hotels and other accommodations in Downtown Santiago to choose from, making this an ideal home base for exploring the greater Santiago area.
If I need to cancel my hotel reservation in Downtown Santiago, will I receive a refund?
Yes! Most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown Santiago.
Where can I learn more about changing or cancelling my trip to Downtown Santiago?
For more details about picking new dates or cancelling your trip to Downtown Santiago, go to https://www.expedia.com/service/.
What is there to do around this Santiago neighborhood?
Fantasilandia, National History Museum, and National Museum of Natural History are fun stops for the whole family while you're in Downtown Santiago. As you're discovering the neighborhood, Palacio de la Moneda and Movistar Arena are some other places worth a visit. Cousino Palace, Museo Historico Militar, and Torre Entel are just a few of the places to visit in and around Downtown Santiago. While you're out sightseeing in Santiago, be sure to visit other sights like Museo de la Solidaridad Salvador Allende or La Moneda Cultural Center.
How can I get around Downtown Santiago and the greater Santiago area?
For a quick way to explore the city, catch a ride on metro transit at Toesca Station, O'Higgins Park Station, or Heroes Station. If you want to venture out of town, Parque Almagro Station is the closest train station. You can also catch a ride at Matta Station.