Downtown Clayton Vacations

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Where to stay in Downtown Clayton

Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Clayton
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Find hotels in Downtown St. Louis

Downtown Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is NT$3,281 per night from Feb 20 to Feb 21
NT$3,281
NT$3,831 total
Feb 20 - Feb 21
includes taxes & fees
8.8/10 Excellent! (3,083 reviews)
Staff always pleasant

Reviewed on 2026/2/2

Clayton Plaza Hotel & Extended Stay
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
The price is NT$15,802 per night from Mar 8 to Mar 9
NT$15,802
NT$18,447 total
Mar 8 - Mar 9
includes taxes & fees
9.2/10 Wonderful! (556 reviews)
Very courteo

Reviewed on 2026/1/13

The Ritz-Carlton, St. Louis
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is NT$4,402 per night from Feb 22 to Feb 23
NT$4,402
NT$5,138 total
Feb 22 - Feb 23
includes taxes & fees
9/10 Wonderful! (241 reviews)
My room was spotless and very well put together.

Reviewed on 2026/1/9

AC Hotel St. Louis Clayton
See all 1,830 properties in Downtown Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown Clayton vacation package cost?
Less than you might think — from just , as a matter of fact! By combining hotels, flights and car rentals into a custom-made travel package, your Downtown Clayton escape is just a few clicks away.
How do I get a cheap travel package to Downtown Clayton?
Imagine all the wonderful things you could do in Downtown Clayton with a pile of extra cash in your wallet. Watch your savings stack up when you combine your travel bookings into a Downtown Clayton vacation package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 air carriers and 1,000,000 properties throughout the world. Whether you're taking off with the whole family or surprising your special someone, organizing a trip to Downtown Clayton is better with a package.
Where should I stay in Downtown Clayton?
Most people who visit Downtown Clayton include both St. Louis Zoo and Cathedral Basilica of St. Louis on their bucket lists. Why not go for a hotel that's close to these iconic attractions?
What are the top hotels in Downtown Clayton?
King Bed, Comfy Environment, Cozy Space and Le Méridien St. Louis Clayton are among the most well-known properties in Downtown Clayton. Why not look up the amenities and facilities at each and then decide?
How far in advance should I book my Downtown Clayton vacation?
Your safest bet is to book early. Air carriers generally advertise flights around a year in advance, and this is a fantastic opportunity to land some rock-bottom prices. Just been told you should take all your vacation days next month? That's alright! Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Downtown Clayton travel package include?
That depends on what sort of escape you're planning. Downtown Clayton vacation deals can include car rentals, hotels and flights. You can mix and match to create the package that works for you! You can also add on activities and experiences after you've booked to land even bigger discounts.
What should I know before booking a Downtown Clayton travel package?
When you book your flights, hotels and car rentals together, you'll walk away with fantastic discounts. Whether you're organizing a beach break in a villa or prefer to stay in a convenient hotel in the city, Expedia will make it happen for less.
Can I choose my airline with a Downtown Clayton Expedia vacation package?
Expedia offers access to more than 550 airline partners worldwide, so you sure can! Simply choose your preferred air carrier and create the perfect Downtown Clayton trip.
If I'm not able to travel, can I cancel my Downtown Clayton vacation package?
It's hard to predict what the future holds, so it's good to know that you can change or cancel your Downtown Clayton vacation package. If you booked in the last 24 hours, you may be eligible for a refund. If it's an older booking, your airline, hotel or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Discover the most popular places to visit in Downtown Clayton

Gateway Arch showing a city, a skyscraper and skyline

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo
Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.

Enterprise Center

Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.

Enterprise Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.