Find hotels in Barrio de Guadalupe, San Cristóbal de las Casas

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Barrio de Guadalupe hotels

Tierra Alta Hostal

Tierra Alta Hostal
3.0 star property
Barrio de Guadalupe
9.6 out of 10, Exceptional, (13)
"I stayed here last week and loved it so much I came back. Everything about this place is exceptional. This will be my to-go place to stay while in San Cris. "
United States
Damaris
Tierra Alta Hostal

Jungla Hotel Boutique

Jungla Hotel Boutique
2.0 star property
Barrio de Guadalupe
10.0 out of 10, Exceptional, (2)
"Todo"
Mexico
Rodolfo antonio
The price is NT$2,111
NT$2,492 total
includes taxes & fees
Dec 27 - Dec 28
Jungla Hotel Boutique

Taller de Juan - Casa Hotel

Taller de Juan - Casa Hotel
3.5 star property
Barrio de Guadalupe
9.6 out of 10, Exceptional, (64)
"We loved the staff and the attention to detail. "
United States
Refugio
Taller de Juan - Casa Hotel

Casavieja

Casavieja
4.0 star property
Barrio de Guadalupe
8.8 out of 10, Excellent, (332)
"Good location and nice staff "
Canada
Max
Casavieja

Hotel Ocho Barrios

Hotel Ocho Barrios
3.0 star property
Barrio de Guadalupe
9.2 out of 10, Wonderful, (33)
"The location was excellent.My room was spacious and comfortable, staff very friendly and breakfast was delicious"
United States
Eduardo
The price is NT$1,654
NT$2,049 total
includes taxes & fees
Dec 25 - Dec 26
Hotel Ocho Barrios

Hotel Jovel

Hotel Jovel
3.0 star property
Barrio de Guadalupe
8.0 out of 10, Very Good, (107)
"NO ME AGRADO QUE EL ESTACIONAMIENTO ESTÁ A DOS CIADRAS Y EL HORARIO ES LIMITADO."
Mexico
ALEJANDRO
The price is NT$1,038
NT$1,225 total
includes taxes & fees
Jan 10 - 2026/1/11
Hotel Jovel

Yagil B&B

Yagil B&B
2.0 star property
Barrio de Guadalupe
The price is NT$1,184
NT$1,397 total
includes taxes & fees
Dec 25 - Dec 26
Yagil B&B

Hotel Parador Margarita

Hotel Parador Margarita
3.5 star property
Barrio de Guadalupe
9.0 out of 10, Wonderful, (145)
"One of the best places I’ve stayed in San Cristobal — old and charming building, but comfortable rooms with modern amenities. Friendly staff, lovely area — central but not noisy."
Canada
Jessica
The price is NT$1,579
NT$1,863 total
includes taxes & fees
Jan 8 - 2026/1/9
Hotel Parador Margarita

Yox Hotel Boutique

Yox Hotel Boutique
2.5 star property
Barrio de Guadalupe
9.2 out of 10, Wonderful, (97)
"Location is perfect everything close to the hotel "
United States
Jose
The price is NT$1,571
NT$1,854 total
includes taxes & fees
Jan 4 - 2026/1/5
Yox Hotel Boutique

Hotel Casa del Sol

Hotel Casa del Sol
2.5 star property
Barrio de Guadalupe
8.8 out of 10, Excellent, (6)
"Friendly good but need to change more details "
United States
wook
The price is NT$1,316
NT$1,553 total
includes taxes & fees
Jan 24 - 2026/1/25
Hotel Casa del Sol

Hotel Cielo y Selva, San Cristobal de las Casas

Hotel Cielo y Selva, San Cristobal de las Casas
3.0 star property
Barrio de Guadalupe
8.6 out of 10, Excellent, (112)
"The staff was very friendly and helpful all the time!"
United States
MAYRA
The price is NT$1,178
NT$1,391 total
includes taxes & fees
Jan 7 - 2026/1/8
Hotel Cielo y Selva, San Cristobal de las Casas

Hotel Tepeyac

Hotel Tepeyac
3.0 star property
Barrio de Guadalupe
9.0 out of 10, Wonderful, (133)
"Clean room, good staff"
United States
Jonathan
Hotel Tepeyac

Hotel Palacio de Moctezuma

Hotel Palacio de Moctezuma
3.5 star property
Zona Centro, 0.8 km from Barrio de Guadalupe
9.2 out of 10, Wonderful, (28)
"The hotel was decorated lovely, had a very cozy feeling the room were clean and spacious. "
United States
Itzel
The price is NT$1,303
NT$1,537 total
includes taxes & fees
Jan 8 - 2026/1/9
Hotel Palacio de Moctezuma

Casa Neek

Casa Neek
4.0 star property
1.4 km from Barrio de Guadalupe
10.0 out of 10, Exceptional, (13)
"Very helpful and friendly staff. Room was beautifully decorated and very clean. Unique location."
Germany
Thomas
The price is NT$3,979
NT$4,695 total
includes taxes & fees
Jan 24 - 2026/1/25
Casa Neek

Hotel Hacienda Don Juan

Hotel Hacienda Don Juan
3.5 star property
2.8 km from Barrio de Guadalupe
8.8 out of 10, Excellent, (458)
"Clean Beautiful Great service Great breakfast "
Canada
Patrick
Hotel Hacienda Don Juan

Guayaba Inn Boutique Hotel

Guayaba Inn Boutique Hotel
4.0 star property
Barrio del Cerrillo, 0.4 km from Barrio de Guadalupe
9.8 out of 10, Exceptional, (259)
"T"
Mexico
Francisco
The price is NT$3,326
NT$3,924 total
includes taxes & fees
Jan 6 - 2026/1/7
Guayaba Inn Boutique Hotel

Hotel Villa Murano

Hotel Villa Murano
3.0 star property
Barrio del Cerrillo, 0.5 km from Barrio de Guadalupe
8.8 out of 10, Excellent, (8)
"Un súper servicio de todos los empleados, muy cómodo el spa, todo limpio y cerca de los puntos de interés de San Cristobal de las Casas"
Mexico
Alberto Roca
Hotel Villa Murano

Casa Santa Lucía

Casa Santa Lucía
3.5 star property
Zona Centro, 0.7 km from Barrio de Guadalupe
10.0 out of 10, Exceptional, (161)
"Nice hotel!, very close to the zocalo"
United States
Pedro
The price is NT$3,158
NT$3,726 total
includes taxes & fees
Jan 23 - 2026/1/24
Casa Santa Lucía

Posada Real de Chiapas

Posada Real de Chiapas
3.0 star property
Zona Centro, 0.8 km from Barrio de Guadalupe
9.2 out of 10, Wonderful, (412)
"Best location ! Amazing staff 🫶 good continental breakfast ☕️ "
United States
LILIANA
The price is NT$2,525
NT$2,979 total
includes taxes & fees
Jan 24 - 2026/1/25
Posada Real de Chiapas

Hotel Sombra del Agua

Hotel Sombra del Agua
3.5 star property
Zona Centro, 1 km from Barrio de Guadalupe
9.4 out of 10, Exceptional, (1000)
"Fantastic location & beautiful colonial building."
United Kingdom
Julia
The price is NT$2,871
NT$3,387 total
includes taxes & fees
Jan 5 - 2026/1/6
Hotel Sombra del Agua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Barrio de Guadalupe

Find the best Barrio de Guadalupe areas and neighborhoods for the activities you enjoy most.

Zona Centro

Unique features of Zona Centro include the museums and gardens. Make a stop by Mesoamerican Museum of Jade or Foro Cultural Kinoki while you're exploring the area.

Santa Lucía

While visiting Santa Lucía, you might make a stop by sights like Santo Domingo Handicraft Market and Arches of Carmen.

Barrio de La Merced

While visiting Barrio de La Merced, you might make a stop by sights like Amber Museum of Chiapas and Regional Costume Museum.

Barrio del Cerrillo

If you're spending some time in Barrio del Cerrillo, Na Bolom Cultural Museum and Ex-Convent of Santo Domingo are top sights worth seeing.

De Cuxtitali

When in De Cuxtitali, you can plan a visit to Na Bolom Cultural Museum and Ex-Convent of Santo Domingo, some noteworthy sights in the nearby area.

Top Barrio de Guadalupe Hotel Reviews

Frequently asked questions

What is Barrio de Guadalupe like?
You'll be sure to have fun visiting San Cristóbal de las Casas's Barrio de Guadalupe neighborhood.
What's a favorite hotel to stay in Barrio de Guadalupe?
Based on Expedia customer reviews, Taller de Juan - Casa Hotel is the highest ranked property in Barrio de Guadalupe. This hotel is a short 8-minute walk from San Cristóbal de las Casas Cathedral, and it offers a restaurant and a bar. Other favorite options in the area include Hotel Ocho Barrios and Hotel Cielo y Selva, San Cristobal de las Casas.
How many hotels are there in the Barrio de Guadalupe area?
Expedia has 61 hotels and other accommodations in Barrio de Guadalupe to choose from, making this an ideal home base for exploring the greater San Cristóbal de las Casas area.
If I need to cancel my hotel reservation in Barrio de Guadalupe, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Barrio de Guadalupe.
Where can I learn more about changing or cancelling my trip to Barrio de Guadalupe?
To find more details about updating your trip to Barrio de Guadalupe or cancelling it, click here.
What is there to do in this San Cristóbal de las Casas neighborhood?
A few places to visit in the area around Barrio de Guadalupe include Na Bolom Cultural Museum, Galeria Studio Cerrillo, and Foro Cultural Kinoki. Café Museo Café and Church of San Nicolás are also worth a visit when you're out sightseeing in San Cristóbal de las Casas.