A historic stone fortress with a central dome and surrounding walls.

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Check availability on Colon Luxury Hotels

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Colon luxury hotels

A balcony with a table, chairs, and a view of a city skyline across a body of water.

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (768 reviews)
  • cleanliness
    Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
The price is NT$13,790
NT$15,169 total
includes taxes & fees
Nov 1 - Nov 2
Sofitel Legend Casco Viejo, Panama City
A poolside area with lounge chairs and a view of the ocean.

2. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
The price is NT$9,620
NT$10,582 total
includes taxes & fees
Nov 27 - Nov 28
JW Marriott Panama
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

3. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (6,142 reviews)
  • cleanliness
    Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
The price is NT$3,899
NT$4,289 total
includes taxes & fees
Nov 24 - Nov 25
Hotel Riu Plaza Panama
A restaurant with multiple dining tables, chairs, and a central water feature.

4. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (370 reviews)
  • cleanliness
    Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
The price is NT$9,695
NT$10,664 total
includes taxes & fees
Oct 29 - Oct 30
Hotel La Compañía Casco Antiguo
A hotel entrance with a central water feature, seating areas, and potted plants.

5. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (768 reviews)
  • cleanliness
    Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
The price is NT$10,178
NT$11,196 total
includes taxes & fees
Nov 22 - Nov 23
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern hotel pool area with lounge chairs and a clear view of the ocean.

6. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
The price is NT$8,559
NT$9,415 total
includes taxes & fees
Nov 20 - Nov 21
Hilton Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.

7. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
The price is NT$8,840
NT$9,724 total
includes taxes & fees
Nov 14 - Nov 15
Waldorf Astoria Panama
A hotel with a pool, beach, and palm trees.

8. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1,002 reviews)
  • cleanliness
    Oceanfront luxury beckons with private beach, indulgent spa services, and refined dining at this beachfront Panama retreat.
The price is NT$6,716
NT$7,388 total
includes taxes & fees
Nov 10 - Nov 11
The Westin Playa Bonita Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

9. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (491 reviews)
  • cleanliness
    Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
The price is NT$6,096
NT$6,706 total
includes taxes & fees
Nov 8 - Nov 9
Hyatt Regency Panama City
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

10. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,829 reviews)
  • cleanliness
    Experience luxury and elegance in a Panamanian retreat with 2 restaurants, a spa, and casino.
The price is NT$4,352
NT$4,787 total
includes taxes & fees
Nov 9 - Nov 10
Megapolis Hotel Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Colon Hotel Reviews

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

10/10 Excellent
"Muy buen espacio"
ELIUD 4-night trip
Posted 9 hours ago
Las Americas Golden Tower Panama

Frequently asked questions

Are you looking for a luxury hotel for your Colon vacation?
Use Expedia to arrange your flight to Panama City (PAC-Marcos A. Gelabert Intl.) airport or Balboa (BLB-Panama Pacifico Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Colon offers. Colon has some interesting things to see and do including Colon 2000 and Colon Free Zone, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Colon?
Sand Diamond Hotel is a luxury hotel with ski-in/ski-out access and a casino, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in Colon?
Planning for the weather is an important factor for making your trip to Colon a success, especially when you're splurging. The hottest months are usually May and September with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Colon are November, July, August, and October, with each month seeing an average of 14 inches of rainfall.
What's there to see and do in Colon?
Take in the sights and attractions that Colon offers with a visit to Colon 2000, Colon Free Zone, and Gamboa Rainforest Resort. If you have extra time while you're in the area, you might want to see Fantastic Casino | Colón 2000 and Fort San Lorenzo.
How can I get around Colon?
It's easier to get around town in style when you know your options. To see more of the larger area, ride aboard one of the trains from Colon Atlantic Passenger Station.