A historic stone fortress with a central dome and surrounding walls.

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Check availability on Colon Luxury Hotels

Tonight
Aug 22 - Aug 23
Tomorrow
Aug 23 - Aug 24
Next weekend
Aug 28 - Aug 30
In two weeks
Sep 4 - Sep 6

Our top choices for Colon luxury hotels

1. Luma Rentals Apartments

Luma Rentals Apartments
Bella Vista
NT$3,982
NT$5,974 total
includes taxes & fees
Sep 20 - Sep 21
Luma Rentals Apartments

2. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
NT$3,114
NT$3,426 total
includes taxes & fees
Aug 28 - Aug 29
Courtyard by Marriott Panama Metromall

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
NT$8,565
NT$9,421 total
includes taxes & fees
Sep 3 - Sep 4
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

4. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
Costa del Este
NT$3,641
NT$5,688 total
includes taxes & fees
Aug 25 - Aug 26
Corporate Stays Arcadia | Executive Furnished Apartments

5. The Westin Panama

The Westin Panama
Costa del Este
NT$7,370
NT$8,107 total
includes taxes & fees
Sep 5 - Sep 6
The Westin Panama

6. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
NT$5,591
NT$6,150 total
includes taxes & fees
Aug 31 - Sep 1
Sheraton Grand Panama

7. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
  • Spectacular waterfront luxury at Panama Canal hotel with premium dining and dual pools.
NT$3,028
NT$3,331 total
includes taxes & fees
Sep 5 - Sep 6
Radisson Hotel Panama Canal

8. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
  • Luxury redefined in Panama City with rooftop pool, premium dining, and concierge services to elevate your urban escape.
NT$5,129
NT$5,642 total
includes taxes & fees
Aug 30 - Aug 31
Marriott Panama Hotel

9. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
NT$8,640
NT$9,504 total
includes taxes & fees
Sep 11 - Sep 12
JW Marriott Panama

10. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
NT$8,674
NT$8,674 total
includes taxes & fees
Aug 24 - Aug 25
Dreams Playa Bonita Panama - All Inclusive
View all properties

Top Colon Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Wonderful hotel"
Mark 3-night trip
Posted 2 hours ago
Hotel Riu Plaza Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent
"Enjoyed my stay even after being charged for a breakfast they said was free."
bruce L 2-night trip
Posted 3 hours ago
Courtyard by Marriott Panama Multiplaza Mall
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

8/10 Good
"Lovely property outside of the city. Easy to get around by Uber. Staff was very helpful and pleasant. Rooms could do with a little more attention to the cleaning. However, housekeeping quickly dealt with any issues when brought to their attention. Microwave, mini fridge, coffeemaker in rooms. Wifi available throughout the property. Pool and Jacuzzi open until 11pm and well lit. Gym facilities rating 8.5/10. Pretty good breakfast with a variety of breads, pastries, pancakes, French toast, pancake syrup, chocolate and caramel syrups, fresh vegetables, fruit, oatmeal, almonds, vegetable broth, boiled and scrambled eggs, you can request an omelet. Sausages, spam, assorted cheeses, cold meats - ham, salami, sometimes chicken wings/beef stew/chicken tenders, steamed vegetables, hash browns. Friendly and attentive wait staff. The breakfast buffet closes off at 10am. The restaurant meals were good. Great view of ships lining up for the canal. Lush property with mango trees. The Amador Causeway is nearby with restaurants such as Mi Ranchito for great and very affordable Panamaian cuisine. Sabroso Panama Restaurant is pricier, catering mostly to tourists wth traditional entertainment starting at around 8:15pm. Worth the visit! I would stay at the Radisson again and definitely in a room with a balcony and view of the Pacific."
Angella 7-night trip
Posted 4 hours ago
Radisson Hotel Panama Canal
Renaissance Panama City Hotel

Renaissance Panama City Hotel

10/10 Excellent
"I was very happy with my stay here. The staff was great. We arrived early and they made a huge effort to get our ready for us early (within 20 minutes). We called for extra towels and they brought them right away. I highly recommend."
Ryan 3-night trip
Posted 6 hours ago
Renaissance Panama City Hotel
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"The check in and check out process was efficient and everything went smoothly. The breakfast buffet is a good introduction to local cuisine with a mix of international flavour."
Tricia 5-night trip
Posted 7 hours ago
Decapolis Hotel Panama City
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

10/10 Excellent
"Rainforest views and Hammock in the balcony"
Rajdeep 1-night trip
Posted 3 days ago
Gamboa Rainforest Reserve

Frequently asked questions

Are you looking for a luxury hotel for your Colon vacation?
Use Expedia to arrange your flight to Panama City (PAC-Marcos A. Gelabert Intl.) airport or Balboa (BLB-Panama Pacifico Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Colon offers. Colon has some interesting things to see and do including Colon 2000 and Colon Free Zone, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Colon?
Sand Diamond Hotel is a luxury hotel with ski-in/ski-out access and a casino, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in Colon?
Planning for the weather is an important factor for making your trip to Colon a success, especially when you're splurging. The hottest months are usually May and September with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Colon are November, July, August, and October, with each month seeing an average of 14 inches of rainfall.
What's there to see and do in Colon?
Take in the sights and attractions that Colon offers with a visit to Colon 2000, Colon Free Zone, and Gamboa Rainforest Resort. If you have extra time while you're in the area, you might want to see Galeta Island Marine Education Center and Fort San Lorenzo.
How can I get around Colon?
It's easier to get around town in style when you know your options. To see more of the larger area, ride aboard one of the trains from Colon Atlantic Passenger Station.