Find Resorts & Hotels with Spas in Clemson, SC

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Check availability on Clemson Resorts & Hotels with Spas

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Recommended hotels in Clemson

Hallway
The Inn at Patrick Square

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (781)
"Clean room. Nice front desk concierge. Very cute hotel"
United States
Anisha
The price is NT$4,648
NT$5,159 total
includes taxes & fees
Dec 15 - Dec 16
The Inn at Patrick Square
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1001)
"Great stay "
United States
Linda
The price is NT$2,890
NT$3,208 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Inn & Suites Clemson - University Area
Lobby lounge
The Abernathy of Clemson

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (557)
"location is amazing! "
United States
colleen
The Abernathy of Clemson
Free breakfast
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1003)
" Clean room, breakfast, staff very nice."
United States
Maria Claudia
The price is NT$2,890
NT$3,208 total
includes taxes & fees
Dec 15 - Dec 16
Best Western Plus Clemson Hotel & Conference Center
Interior
Clemson Memorabilia House

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.8 out of 10, Exceptional, (9)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is NT$2,589
NT$7,202 total
includes taxes & fees
Dec 15 - Dec 16
Clemson Memorabilia House
Cafe
Courtyard Marriott Clemson

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (523)
"Great property "
United States
Shaun
The price is NT$3,341
NT$3,708 total
includes taxes & fees
Dec 21 - Dec 22
Courtyard Marriott Clemson
Lobby
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (743)
"Staff was amazing and our room was clean and comfortable. "
United States
Amanda R
The price is NT$5,272
NT$5,852 total
includes taxes & fees
Dec 15 - Dec 16
The Shepherd Hotel Downtown Clemson
Free daily continental breakfast
Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
Clemson
7.0 out of 10, Good, (197)
"Rooms were clean. Check in was easy. TV and AC both worked great. Conveniently located to dining and shopping options. No issues or complaints. Would stay again. "
United States
Sean
The price is NT$2,637
NT$2,928 total
includes taxes & fees
Dec 16 - Dec 17
Days Inn by Wyndham Clemson
Exterior
Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (950)
"Had a great stay at this hotel. Conveniently located near restaurants. "
United States
Kelly
The price is NT$3,681
NT$4,086 total
includes taxes & fees
Jan 2 - 2026/1/3
Holiday Inn Express & Suites Clemson by IHG
Golf
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.6 out of 10, Exceptional, (960)
"Great place to stay!"
United States
Mindi
The price is NT$4,648
NT$5,159 total
includes taxes & fees
Dec 15 - Dec 16
Clemson University's James F. Martin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Clemson Hotel Reviews

Courtyard Marriott Clemson

Courtyard Marriott Clemson

10/10 Excellent
"Clean room, friendly staff."
Cynthia 1-night trip
Posted 3 weeks ago
Courtyard Marriott Clemson

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Frequently asked questions

Looking for a spa hotel in Clemson?
Treat yourself to some pampering and book a hotel with a spa. Check out the live music scene and local architecture in Clemson—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.
What's there to see and do in Clemson?
Enjoy all that Clemson has to offer when you visit Fort Hill, Memorial Stadium, and Littlejohn Coliseum. If you have extra time while you're in the area, you might want to stop by Brooks Center for the Performing Arts and South Carolina Botanical Gardens.
What is a Clemson spa hotel?
Spa hotels in Clemson provide lodging and have an on-site spa offering services like couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.