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Find Resorts & Hotels with Spas in Clarksville, IN

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Check availability on Clarksville Resorts & Hotels with Spas

Our top choices for Clarksville hotels with a spa

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3842)
"Beautiful room and great hospitality. "
United States
Chase
The price is NT$4,157
NT$4,891 total
includes taxes & fees
Dec 15 - Dec 16
Galt House Hotel Trademark Collection by Wyndham
Indoor pool
Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination
3.5 star property
Elizabeth
8.2 out of 10, Very Good, (1009)
"The room was very clean, the staff was very friendly and helpful."
United States
Judy
The price is NT$2,220
NT$3,088 total
includes taxes & fees
Dec 21 - Dec 22
Caesars Southern Indiana - A Caesars Rewards Destination
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1722)
"Clean room, friendly staff"
United States
Jill
The price is NT$5,214
NT$6,135 total
includes taxes & fees
Jan 2 - 2026/1/3
Omni Louisville Hotel
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1001)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is NT$4,334
NT$5,256 total
includes taxes & fees
Jan 1 - 2026/1/2
21c Museum Hotel Louisville
Full-size fridge, microwave, oven, stovetop
The Reserve on Main

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is NT$4,490
NT$6,771 total
includes taxes & fees
Dec 16 - Dec 17
The Reserve on Main
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

Central Park Bed & Breakfast
4.0 star property
Old Louisville
9.4 out of 10, Exceptional, (57)
"Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed."
United States
John
The price is NT$4,228
NT$4,907 total
includes taxes & fees
Dec 21 - Dec 22
Central Park Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Clarksville Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"Clean room, safe parking, and we love the bar! "
julie 1-night trip
Posted 12 hours ago
Galt House Hotel Trademark Collection by Wyndham

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Frequently asked questions

Looking for a spa hotel in Clarksville?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Clarksville. Enjoy the shopping and waterfalls during your vacation. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Clarksville?
When you're in Clarksville, enjoy exploring the sights and attractions here including Derby Dinner Playhouse, Falls of the Ohio State Park, and Ohio River Valley. If you have a little extra time during your trip, you might want to check out Atlantis Waterpark and Old Clarksville Site.
What is a Clarksville spa hotel?
Spa hotels in Clarksville provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.