A city skyline with a prominent arch bridge and a lit bridge over a calm river reflecting city lights.

Find Resorts & Hotels with Spas in Chesterfield, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Chesterfield Resorts & Hotels with Spas

Tonight
Oct 24 - Oct 25
Tomorrow
Oct 25 - Oct 26
Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Our top choices for Chesterfield hotels with a spa

A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bakery display case with various pastries and cakes.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
NT$5,190
NT$6,607 total
includes taxes & fees
Nov 23 - Nov 24
Ameristar Casino Resort and Spa
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A hotel room with two beds, a large padded headboard, a flat-screen TV, a window with a city view, and a small side table with a plant.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.
A modern lobby with a large glass sphere, seating areas, and a reception desk.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
NT$4,683
NT$5,639 total
includes taxes & fees
Nov 15 - Nov 16
21C Museum Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A bar area with leather seating, a bar counter, and shelves of bottles.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.

3. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
NT$18,876
NT$22,035 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

4. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
NT$12,225
NT$14,295 total
includes taxes & fees
Oct 26 - Oct 27
Four Seasons Hotel St Louis
A two-story building with a dark entrance, large windows, and a brick facade.
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A room with a fireplace, curtains, a woven basket, and a chair.

5. Truitt Hotel

Truitt Hotel
Lafayette Square
NT$5,477
NT$6,649 total
includes taxes & fees
Oct 26 - Oct 27
Truitt Hotel
View all properties

Choose what matters most at spa hotels in Chesterfield

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Chesterfield Hotel Reviews

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

10/10 Excellent
"Kids had a couple days off from school so we decided to do a staycation. Perfect spot for a quick getaway. The kids played in the pool for hours, dinner and breakfast included. We will definitely be back this winter."
John 1-night trip
Posted 2 hours ago
Drury Plaza Hotel St. Louis Chesterfield
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Excellent location and nice place!"
Briana 2-night trip
Posted 3 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Loved the location, amenities and large room with comfortable bed. We were able to walk to Enterprise Center. Particularly enjoyed the happy hour and breakfast. Did not appreciate the noise from the garbage collectors handling the huge dumpsters around 4am. For an upscale quality hotel you should contract to have quiet hours like midnight to 8am with any businesses your guest rooms face."
Debbie 1-night trip
Posted 1 day ago
Drury Plaza Hotel St. Louis Union Station
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"We enjoyed the fresh popcorn and it was within walking distance from the train station."
Tamela 1-night trip
Posted 2 days ago
Pear Tree Inn St. Louis Near Union Station

Frequently asked questions

Looking for a spa hotel in Chesterfield?
Soothe the senses with some time in one of our wonderful spa hotels. Travelers highly recommend the restaurants in Chesterfield. Be sure to pay a visit to the museums during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in Chesterfield?
Take in some sights and attractions while you're in Chesterfield by visiting The Factory, St. Louis Premium Outlets, and Missouri River. If you have some spare time during your trip, you might want to check out Chesterfield Amphitheater and Topgolf.
What is a Chesterfield spa hotel?
Spa hotels in Chesterfield provide lodging and have a full on-site spa which offers services such as facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

Explore a world of travel with Expedia