Find Resorts & Hotels with Spas in Brentwood, MO

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Check availability on Brentwood Resorts & Hotels with Spas

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Brentwood hotels with a spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1011)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is NT$5,624
NT$7,095 total
includes taxes & fees
Jan 11 - 2026/1/12
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1517)
"Hotel was comfortable, clean and unique. All staff was wonderful "
United States
Sharon
The price is NT$4,498
NT$5,417 total
includes taxes & fees
Jan 5 - 2026/1/6
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1001)
"Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home. "
United States
Lynne
The price is NT$13,033
NT$15,239 total
includes taxes & fees
Jan 2 - 2026/1/3
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (554)
"The stay was ok even though nothing was explained to be. The hours of restaurant, where the gym is located about the bar in the room nothing. "
United States
Shemelle
The price is NT$15,671
NT$18,293 total
includes taxes & fees
Jan 2 - 2026/1/3
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Brentwood Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"It was nice clean and the front desk help were very professional. "
Peter 1-night trip
Posted 12 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

Looking for a spa hotel in Brentwood?
Forget the stress of everyday life and book yourself a lush spa hotel. Travelers recommend the gourmet restaurants in Brentwood. Be sure to enjoy the shopping during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Brentwood?
Enjoy all that Brentwood has to offer when you visit St. Louis Union Station, Busch Stadium, and Saint Louis Galleria Mall. If you have some spare time during your trip, you might want to check out St. Louis Art Museum and St. Louis Zoo.
What is a Brentwood spa hotel?
Spa hotels in Brentwood provide lodging and have an on-site spa which offers services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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