A large suspension bridge, industrial cranes, and a calm river.

Panama Canal Zone 5 Stars Hotels

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Check availability on Panama Canal Zone 5 Star Hotels

Tonight
Sep 27 - Sep 28
Tomorrow
Sep 28 - Sep 29
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Panama Canal Zone 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A modern hotel room with a dining area, a TV, and a city view.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Sandrelly
NT$4,371
NT$4,808 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
NT$8,306
NT$9,137 total
includes taxes & fees
Oct 17 - Oct 18
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
NT$12,575
NT$13,832 total
includes taxes & fees
Oct 6 - Oct 7
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
NT$4,033
NT$4,436 total
includes taxes & fees
Oct 9 - Oct 10
Renaissance Panama City Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Nemanja
NT$8,866
NT$9,753 total
includes taxes & fees
Oct 24 - Oct 25
JW Marriott Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A modern interior with a central seating area, potted plants, and a staircase.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
sheldon z
NT$5,938
NT$6,532 total
includes taxes & fees
Oct 4 - Oct 5
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A pool with a central water feature, surrounded by seating areas and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Shelly-Ann
NT$8,537
NT$9,390 total
includes taxes & fees
Oct 15 - Oct 16
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.

8. W Panama

W Panama
Bella Vista
United States
Nikkia
NT$7,596
NT$8,355 total
includes taxes & fees
Oct 10 - Oct 11
W Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern interior with a spiral staircase, a large window, and a seating area.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Kevin
NT$7,786
NT$8,564 total
includes taxes & fees
Oct 24 - Oct 25
Hilton Panama
A hotel with a pool, beach, and palm trees.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Anna
NT$6,545
NT$7,199 total
includes taxes & fees
Oct 7 - Oct 8
The Westin Playa Bonita Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A person performing a yoga pose in a living room with a large window and a sofa.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
NT$6,721
NT$7,393 total
includes taxes & fees
Oct 2 - Oct 3
Bristol Panama, a Registry Collection Hotel

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
NT$3,005
NT$3,320 total
includes taxes & fees
Sep 29 - Sep 30
Waymore Hotel Spa and Casino
A modern hotel room with a sofa, armchair, and a television.

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
NT$7,142
NT$7,888 total
includes taxes & fees
Oct 20 - Oct 21
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
NT$4,319
NT$4,960 total
Oct 6 - Oct 7
includes taxes & fees
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
NT$6,039
NT$6,643 total
Sep 29 - Sep 30
includes taxes & fees
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
NT$5,101
NT$5,611 total
Sep 28 - Sep 29
includes taxes & fees
8.6/10 Excellent! (1,762 reviews)
Megapolis Hotel Panamá
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Explore the relaxing area of Panama Canal Zone—natural beauty, golf courses, and popular sights like Albrook Shopping Mall.

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A large suspension bridge, industrial cranes, and a calm river.

Top Panama Canal Zone Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone depends on things like when you plan to go and the length of your vacation. Our insider tip for bagging an awesome deal? Use our pricing filters to compare all of the available accommodations for your selected dates.
  • Search for the lowest price per night from NT$4,960
What makes a hotel 5 stars in Panama Canal Zone?
In Panama Canal Zone, a hotel must offer a specific number of upscale features to earn 5 stars. These may include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their exceptional standard of service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer extra touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Expedia's filters are the quickest way to narrow down what you're looking for. Check the "All inclusive" and "5-star" boxes to see the most luxurious hotels in Panama Canal Zone where your meals, room, entertainment and activities are included in the price. At these getaways, your vacation is pure extravagance from the moment you check in.