A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse Luxury Hotels

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Syracuse luxury hotels

A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia
9.2 out of 10, Wonderful, (111 reviews)
  • cleanliness
    Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
The price is NT$22,372
NT$24,970 total
includes taxes & fees
Nov 3 - Nov 4
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A spa room with a large window, a hot tub, and two candles.

2. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (224 reviews)
  • cleanliness
    Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
The price is NT$11,060
NT$12,528 total
includes taxes & fees
Oct 30 - Oct 31
Dimora Caiammari Luxury Hotel & Spa
A large swimming pool with a modern building in the background.

3. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (99 reviews)
  • cleanliness
    Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
The price is NT$10,617
NT$12,041 total
includes taxes & fees
Nov 17 - Nov 18
Wellness & Spa Hotel Principe di Fitalia
A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.

4. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.2 out of 10, Wonderful, (286 reviews)
  • cleanliness
    Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
The price is NT$8,125
NT$9,299 total
includes taxes & fees
Nov 29 - Nov 30
Ortea Palace Hotel, Sicily, Autograph Collection
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.

5. Minareto

Minareto
5.0 star property
Syracuse
8.8 out of 10, Excellent, (283 reviews)
  • cleanliness
    Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
The price is NT$10,093
NT$11,463 total
includes taxes & fees
Nov 6 - Nov 7
Minareto
A balcony with a view of the sea, a cactus, and potted plants.

6. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (640 reviews)
  • cleanliness
    Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
The price is NT$8,579
NT$9,798 total
includes taxes & fees
Nov 16 - Nov 17
Grand Hotel Ortigia Siracusa
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.

7. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (300 reviews)
  • cleanliness
    Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
The price is NT$4,929
NT$5,783 total
includes taxes & fees
Nov 5 - Nov 6
Caportigia Boutique Hotel
An outdoor seating area with sofas, a table with candles, and lanterns.

8. Donna Coraly Country Boutique Hotel

Donna Coraly Country Boutique Hotel
Syracuse
9.8 out of 10, Exceptional, (12 reviews)
The price is NT$9,449
NT$10,756 total
includes taxes & fees
Oct 31 - Nov 1
Donna Coraly Country Boutique Hotel
A stone-walled interior with a reception desk, two wall-mounted lamps, and a small table with a lamp.

9. Seven Rooms Villadorata

Seven Rooms Villadorata
Noto
10.0 out of 10, Exceptional, (23 reviews)
The price is NT$22,775
NT$25,270 total
includes taxes & fees
Nov 7 - Nov 8
Seven Rooms Villadorata
A hotel room with a four-poster bed, a sofa, a small table with fruit and drinks, and a wooden wardrobe.

10. Il San Corrado di Noto Luxury Resort

Il San Corrado di Noto Luxury Resort
5.0 star property
Noto
10.0 out of 10, Exceptional, (15 reviews)
  • cleanliness
    Mediterranean luxury resort with private beach access, full-service spa, and poolside dining in rural Sicily.
The price is NT$41,111
NT$45,583 total
includes taxes & fees
Oct 30 - Oct 31
Il San Corrado di Noto Luxury Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Syracuse Hotel Reviews

Grand Hotel Villa Politi

Grand Hotel Villa Politi

10/10 Excellent
"It’s such a special grand old hotel. The lookout from our balcony was like a ship porthole, offering this really great view of the waterfront and property. Breakfast was top-notch. All in, a delightful stay!"
Jennifer 1-night trip
Posted 1 day ago
Grand Hotel Villa Politi

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.