A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse Luxury Hotels

Tonight
Sep 13 - Sep 14
Tomorrow
Sep 14 - Sep 15
Next weekend
Sep 18 - Sep 20
In two weeks
Sep 25 - Sep 27

Our top choices for Syracuse luxury hotels

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
NT$22,719
NT$25,358 total
includes taxes & fees
Sep 17 - Sep 18
Grand Hotel Des Ètrangers - The Leading Hotels of the World

2. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
NT$18,687
NT$20,922 total
includes taxes & fees
Sep 14 - Sep 15
Ortea Palace Hotel, Sicily, Autograph Collection

3. Minareto

Minareto
Syracuse
  • Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
NT$14,563
NT$16,386 total
includes taxes & fees
Sep 21 - Sep 22
Minareto

4. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
NT$13,864
NT$15,618 total
includes taxes & fees
Sep 30 - Oct 1
Wellness & Spa Hotel Principe di Fitalia

5. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
  • Luxurious Mediterranean retreat offers memory foam beds, designer toiletries, and sea-view rooftop terrace in Ortigia.
NT$12,871
NT$14,525 total
includes taxes & fees
Oct 2 - Oct 3
Charme Hotel Henry's House

6. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
  • Relax in a grand Beaux Arts hotel in Ortigia, where upscale comfort meets historic charm steps from Syracuse Cathedral.
NT$11,701
NT$13,238 total
includes taxes & fees
Sep 27 - Sep 28
Palazzo Artemide - VRetreats, SLH Collection

7. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
  • Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
NT$11,412
NT$12,920 total
includes taxes & fees
Oct 7 - Oct 8
Grand Hotel Ortigia Siracusa

8. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
  • Historic charm meets seaside luxury in Syracuse with private balconies, rainfall showers, and sea-view breakfast.
NT$10,721
NT$12,161 total
includes taxes & fees
Sep 15 - Sep 16
Algila' Ortigia Charme Hotel

9. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
NT$10,571
NT$11,995 total
includes taxes & fees
Oct 2 - Oct 3
Dimora Caiammari Luxury Hotel & Spa

10. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
NT$7,508
NT$8,626 total
includes taxes & fees
Oct 1 - Oct 2
Caportigia Boutique Hotel
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Top Syracuse Hotel Reviews

Grand Hotel Villa Politi

Grand Hotel Villa Politi

8/10 Good
"It had the old historic charm. The price was a good value for the room. If ever gets a remodel as it needs some Upgrading them then the price would be much higher. Nice pool. Staff needs to be a little more helpful and friendly."
Denise 1-night trip
Posted 15 hours ago
Grand Hotel Villa Politi
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

8/10 Good
"This hotel is well situated in Ortigia and is in a lovely old building. We enjoyed the staff, the bar and the breakfast. However we were misled by our room booking on Expedia. We expect d a room with a view of a mediterranean garden. We got a room facing an inner area- the light well - which afforded very little natural light in the room.band faced another bedroom’s window. The room was very small, with the shower in a closet area, and the toilet in a room on the other side of the bedroom. We asked to move but there was nothing available or offered for the two nights we stayed. All for $480/night. I expected more and would recommend that you book this hotel with caution if you value nice accommodation."
Anne 2-night trip
Posted 2 days ago
Algila' Ortigia Charme Hotel
Charme Hotel Henry's House

Charme Hotel Henry's House

10/10 Excellent
"Really cute boutique hotel with a lot of charm and character. Cozy, welcoming, and in a super convenient location right in Ortigia. We really enjoyed our stay!"
Ton-Duc David 2-night trip
Posted 4 days ago
Charme Hotel Henry's House
 Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"Clean room , service , staff , shops near , big room"
Louis-Philippe 2-night trip
Posted 4 days ago
Palazzo Artemide - VRetreats, SLH Collection
Eureka Palace Hotel Spa

Eureka Palace Hotel Spa

8/10 Good
"The rooms were spacious and clean. The spa was also very good and well maintained"
IKECHUKWU 6-night trip
Posted 8 days ago
Eureka Palace Hotel Spa
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"Old world Italian charm and great service. Would have preferred something more centrally located with a pool and better breakfast."
Karen 3-night trip
Posted 2 weeks ago
Grand Hotel Ortigia Siracusa
Hotel Parco delle Fontane

Hotel Parco delle Fontane

10/10 Excellent
"Please clarify the specific procedures or instructions for gaining access to the facility, particularly regarding the address displayed at the gate."
Salvatore 1-night trip
Posted 3 weeks ago
Hotel Parco delle Fontane

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Des Ètrangers - The Leading Hotels of the World and Grand Hotel Ortigia Siracusa are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Teatro dei Pupi.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

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