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Sep 26 - Sep 27
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Sep 27 - Sep 28
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Our top choices for Santiago Este hotels

A pool surrounded by palm trees and a tiled roof structure.
A tree in a stone planter in a well-lit indoor space with a stone wall and a door in the background.
A building with a curved facade, a balcony with metal railings, and a door with a sign.
A hallway with a glass partition leading to a dining area, a stone wall, and a metal gate with decorative patterns.

1. Hotel Gran David

Hotel Gran David
Santiago
United States
Roxani
NT$2,429
NT$2,672 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Gran David
A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.
A restaurant with booths and tables, wooden paneling, and green plants.
A spacious lobby with modern seating, a central coffee table, and decorative hanging lights.
A spacious lobby with a central water feature, multiple seating areas, and a curved ceiling with hanging lights.

2. Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
United States
Ismael
NT$2,858
NT$3,144 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Mykonos Panama
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.
A hotel room with two single beds, a desk with a chair, a television, and a door.
A bathroom with a tiled shower wall, a sink, and a towel rack.
A hotel room with a dark wooden desk, two cushioned chairs, a large mirror, and two table lamps.

3. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
United States
James
NT$1,646
NT$1,811 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Plaza Los Tucanes
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
A spacious dining area with high ceilings, large windows, and natural light. Tables are set with chairs and centerpieces.
A hammock suspended between two white walls in a room with a balcony.
A multi-story hotel with balconies, a pool, and a reflection in the water.

4. HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
United States
Hedwig
NT$2,429
NT$2,672 total
includes taxes & fees
Sep 28 - Sep 29
HOTEL VISTA LAGO
A beach with a wide sandy shore and gentle waves.
A building with a thatched roof, a signboard with text, and a parked car.
A child crossing a rope bridge over water, with a person assisting.
A table set with a variety of food items, including pastries, fruits, and nuts, arranged on a table with a decorative centerpiece.

5. olivias village room

olivias village room
Capellania
NT$1,286
NT$4,702 total
includes taxes & fees
Sep 28 - Sep 29
olivias village room
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Top Santiago Este Hotel Reviews

HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"Todo perfecto"
Michele 2-night trip
Posted 7 days ago
HOTEL VISTA LAGO
Hotel Mykonos Panama

Hotel Mykonos Panama

8/10 Good
"Las habitaciones están limpias y cómodas, el desayuno está bueno, pero faltan mejorar opciones de proteina; el personal de la recepción, Bar y seguridad son super amable y atento sin embargo el personal del restaurante y piscina (guarda vidas) deben trabajar en trato al público para que mejoren el trabajo que realizan ya que el hotel en sí es muy bueno, completo y cómodo."
iran 2-night trip
Posted 7 days ago
Hotel Mykonos Panama
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"Excelente"
Olopilel 1-night trip
Posted 1 month ago
Hotel Plaza Los Tucanes
Hotel Galería

Hotel Galería

10/10 Excellent
"Hay un restaurante en el hotel con desayuno y comida económica y muy sabrosa. La ubicación del hotel es muy céntrica. Es seguro. Tiene centro comercial al lado. Parqueo de carro seguro. Es perfecto para una visita a Santiago."
Lionel 1-night trip
Posted 6 months ago
Hotel Galería

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Frequently asked questions

Where is the best place for a stay in Santiago Este?
Located 14.9 mi (24 km) from the heart of Santiago Este, Hotel Mykonos Panama is a top choice for your stay based on our traveler data. Two other options for your stay in the area are Hotel Gran David and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in Santiago Este.
If I need to cancel my hotel reservation in Santiago Este, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santiago Este.
Where can I learn more about changing or cancelling my trip to Santiago Este?
For additional details about changing or cancelling your trip to Santiago Este, head over to our customer service page.
What is staying in Santiago Este like?
Travelers to Santiago Este will find plenty to explore and enjoy. There are 16 hotels and other accommodations in the surrounding area. Find out more about Santiago Este.
What is there to see in Santiago Este?
Places to visit in the wider area include Stella Sierra Regional Museum, Parque Acuatico Italia Guadalupe Panama, and Los Pozos Termales. You'll also find Museum of Salt and Sugar and Playa Bella Vista in the area. Check out what more to see and do in Expedia's Santiago Este guide.
What's the weather like in Santiago Este?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santiago Este are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.