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Dec 20 - Dec 21
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Dec 21 - Dec 22
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Dec 26 - Dec 28
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Our top choices for Santa María hotels

Deluxe Suite, 1 King Bed, Pool View | Minibar, free WiFi, bed sheets
Lar Syrah

Lar Syrah

Lar Syrah
2.0 star property
Ruta Independencia, 2.1 km from Santa María
9.4 out of 10, Exceptional, (9)
"Estupendo alojamiento. La ubicación es excelente y las instalaciones son bonitas, modernas y limpias. Servicio atento, Araceli nos apoyó con recomendaciones y para solicitar un taxi. Muy recomendable."
Mexico
Elizabeth
The price is NT$4,374
NT$5,205 total
includes taxes & fees
Jan 15 - 2026/1/16
Lar Syrah
Classic Double Room, Courtyard View | View from room
Casa Arrona Oaxaca

Casa Arrona Oaxaca

Casa Arrona Oaxaca
3.0 star property
Ruta Independencia, 1.4 km from Santa María
10.0 out of 10, Exceptional, (11)
"Excelente atención. Esperemos que siga igual"
Mexico
Martha Penelope
The price is NT$4,684
NT$5,574 total
includes taxes & fees
Jan 15 - 2026/1/16
Casa Arrona Oaxaca
Daily continental breakfast (MXN 320 per person)
Hotel San Felipe

Hotel San Felipe

Hotel San Felipe
3.0 star property
San Felipe del Agua, 3.4 km from Santa María
10.0 out of 10, Exceptional, (1)
"Fue una estancia muy tranquila. Sería ideal el agua templada de la alberca.en el baño de la habitación sería agradable un estractor eléctrico de vapor por ducha y uso del sanitario. Las habitaciones están perfectas las camas super cómodas las almohadas también son cómodas.. y agradables.. El TV jamás me funciono el control y el aire acondicionado no lo use. El restaurante muy agradable y el servicio super bien. Espero regresar muy pronto.."
Mexico
Nenufar
The price is NT$3,133
NT$3,728 total
includes taxes & fees
Jan 3 - 2026/1/4
Hotel San Felipe
Terrace/patio
Casa Acueducto

Casa Acueducto

Casa Acueducto
4.0 star property
1.5 km from Santa María
9.6 out of 10, Exceptional, (31)
" Host were super friendly, Conveniently located within walking distance from many places. Place was always clean,"
United States
JOSE E
Casa Acueducto
Standard Double Room, Balcony, City View | In-room safe, laptop workspace, blackout drapes, free WiFi
Hotel Casa Kabii

Hotel Casa Kabii

Hotel Casa Kabii
2.0 star property
Oaxaca Centro, 1.7 km from Santa María
9.6 out of 10, Exceptional, (5)
"HOTEL PEQUEÑO, LIMPIO, BUENA ATENCION, CERCA ZOCALO OAXACA Y MUY TRANQUILO. LO RECOMIENDO "
Mexico
José Antonio
The price is NT$3,235
NT$3,849 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Casa Kabii
Exterior
Hotel Ferri

Hotel Ferri

Hotel Ferri
3.0 star property
Oaxaca Centro, 1.9 km from Santa María
8.8 out of 10, Excellent, (30)
"Room was clean & the staff was very nice & helpful. I would stay here again in future trips."
United States
Gabriela
The price is NT$3,705
NT$4,409 total
includes taxes & fees
Dec 23 - Dec 24
Hotel Ferri
Interior
ArcoSodi Hotel Boutique

ArcoSodi Hotel Boutique

ArcoSodi Hotel Boutique
3.0 star property
Ruta Independencia, 2.3 km from Santa María
9.6 out of 10, Exceptional, (55)
"Breakfast is good. The locationbosbgood too"
United States
Francisco Raimundo
ArcoSodi Hotel Boutique
Luxury Villa | Terrace/patio
Rooftop Hot Tub 3 levels 5br in Villa

Rooftop Hot Tub 3 levels 5br in Villa

Rooftop Hot Tub 3 levels 5br in Villa
5.0 star property
3.3 km from Santa María
10.0 out of 10, Exceptional, (3)
"Lovely interior, comfortable bedrooms, and clean space. There is plenty of space for large groups and each bedroom has its bathroom. The terrace and the rooftop were great."
United States
Ana
The price is NT$14,934
NT$24,908 total
includes taxes & fees
Dec 22 - Dec 23
Rooftop Hot Tub 3 levels 5br in Villa
Terrace/patio
Lidia Anturios Suites

Lidia Anturios Suites

Lidia Anturios Suites
2.0 star property
Oaxaca Centro, 2.6 km from Santa María
9.4 out of 10, Exceptional, (13)
"Todo muy bien "
Mexico
Conrado
The price is NT$1,387
NT$1,651 total
includes taxes & fees
Jan 18 - 2026/1/19
Lidia Anturios Suites
Terrace/patio
Hotel Rustiko

Hotel Rustiko

Hotel Rustiko
3.0 star property
San Sebastián Tutla, 6.9 km from Santa María
8.4 out of 10, Very Good, (44)
"They have cockroaches in the room. The room wasn’t very clean."
United States
Librado
The price is NT$1,654
NT$1,968 total
includes taxes & fees
Jan 3 - 2026/1/4
Hotel Rustiko
Property entrance
Casa Hidalgo Hotel Boutique

Casa Hidalgo Hotel Boutique

Casa Hidalgo Hotel Boutique
3.5 star property
Oaxaca Centro, 1.7 km from Santa María
9.6 out of 10, Exceptional, (41)
"Great location breakfast and staff"
United States
mohsen
The price is NT$5,624
NT$6,692 total
includes taxes & fees
Dec 21 - Dec 22
Casa Hidalgo Hotel Boutique
Family Studio, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets
Hotel escalada - Oax Up Suites

Hotel escalada - Oax Up Suites

Hotel escalada - Oax Up Suites
2.5 star property
2.8 km from Santa María
8.4 out of 10, Very Good, (54)
"The hotel is very functional, simple and minimalist. Everything worked fine, parking was very safe and efficient. The same goes for the rooms, no luxury just a clean room and comfortable bed. I would stay here again."
United States
Gerardo
The price is NT$2,116
NT$2,518 total
includes taxes & fees
Jan 8 - 2026/1/9
Hotel escalada - Oax Up Suites
28-inch flat-screen TV with cable channels
Hotel Antiguo Fortin

Hotel Antiguo Fortin

Hotel Antiguo Fortin
2.5 star property
0.5 km from Santa María
7.6 out of 10, Good, (122)
"Good place to stay "
United States
Nidia
Hotel Antiguo Fortin
Outdoor pool
Hotel Santa Helena Plaza

Hotel Santa Helena Plaza

Hotel Santa Helena Plaza
2.5 star property
Oaxaca Centro, 1.7 km from Santa María
8.4 out of 10, Very Good, (93)
"Loved the location, just a short walk to the Mercado and Zocalo. "
United States
elizabeth
The price is NT$2,274
NT$2,707 total
includes taxes & fees
Jan 19 - 2026/1/20
Hotel Santa Helena Plaza
Standard Double Room, 1 Double Bed | Desk, laptop workspace, free WiFi, bed sheets
HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS
2.0 star property
Oaxaca Centro, 2 km from Santa María
9.0 out of 10, Wonderful, (195)
"Nice place to stay. Very clean and good value. Good location."
United States
Patrick
The price is NT$1,072
NT$1,275 total
includes taxes & fees
Jan 18 - 2026/1/19
HOTEL POSADA DON MATIAS
KUNI | In-room safe, blackout drapes, iron/ironing board, free WiFi
Flavia Hotel

Flavia Hotel

Flavia Hotel
3.0 star property
San Felipe del Agua, 5.2 km from Santa María
9.0 out of 10, Wonderful, (84)
"Todo excelente "
Mexico
Montserrat
The price is NT$6,619
NT$7,876 total
includes taxes & fees
Jan 13 - 2026/1/14
Flavia Hotel
Yoga
Los Olivos Spa

Los Olivos Spa

Los Olivos Spa
3.0 star property
Calzada Madero, 0.6 km from Santa María
8.2 out of 10, Very Good, (184)
"My family stayed here for five nights total and it was the best hotel for us. Great service, clean, with a very nice restaurant with delicious food. We tried a massage and that was wonderful as well! The hotel's landscape and garden are gorgeous and well-maintained. Thank you!"
United States
Aileen
The price is NT$2,793
NT$3,324 total
includes taxes & fees
Dec 21 - Dec 22
Los Olivos Spa
Interior
Hotel Oaxaca Inn Reforma

Hotel Oaxaca Inn Reforma

Hotel Oaxaca Inn Reforma
3.0 star property
Reforma, 2.3 km from Santa María
8.0 out of 10, Very Good, (62)
"Excellent service! "
United States
Fernando
The price is NT$2,130
NT$2,534 total
includes taxes & fees
Jan 5 - 2026/1/6
Hotel Oaxaca Inn Reforma
Courtyard
Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca
5.0 star property
Ruta Independencia, 2 km from Santa María
9.6 out of 10, Exceptional, (669)
"Great staff, beautiful rooms, wonderful food. Also perfect location."
United States
John Lester
The price is NT$8,390
NT$9,984 total
includes taxes & fees
Jan 18 - 2026/1/19
Grand Fiesta Americana Oaxaca
Property amenity
City Centro by Marriott Oaxaca

City Centro by Marriott Oaxaca

City Centro by Marriott Oaxaca
3.5 star property
Jalatlaco, 2.4 km from Santa María
9.0 out of 10, Wonderful, (759)
"I absolutely loved my stay at city centro. It’s beautiful, the room was perfect, the staff & amenities were 10/10 and the bed was comfortable. I will definitely be back & will recommend this hotel to all my friends and family when visiting Oaxaca. "
United States
Armando Daniel
The price is NT$5,331
NT$6,344 total
includes taxes & fees
Jan 6 - 2026/1/7
City Centro by Marriott Oaxaca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa María

Find the best Santa María areas and neighborhoods for the activities you enjoy most.
Oaxaca which includes a city
Photo by PhotoJoy
Open Photo by PhotoJoy

Oaxaca Centro

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

Ruta Independencia

If you're spending some time in Ruta Independencia, Oaxaca Ethnobotanical Garden and Jardín Etnobotánico are top sights worth seeing.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

Reforma

If you're spending some time in Reforma, Plaza Mazari and Plaza Parque are top sights worth seeing.

San Agustín Yatareni

While there might not be top attractions in San Agustín Yatareni, you can explore the larger area and discover places like El Llano Park and Oaxaca Ethnobotanical Garden.

Top Santa María Hotel Reviews

Casa Mayahuel

Casa Mayahuel

10/10 Excellent
"Cleanness Hotel is new Staff was nice "
Mario 2-night trip
Posted 4 days ago
Casa Mayahuel

Frequently asked questions

What is Santa María like?
Travelers to the Santa María neighborhood in Oaxaca will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Santa María, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best options available in Santa María.
Where can I learn more about changing or cancelling my trip to Santa María?
For additional details about rescheduling or cancelling your trip to Santa María, head over to our customer service page.
What is there to do in this Oaxaca neighborhood?
Cerro del Fortín, Parque Juarez El Llano, and Auditorio Guelaguetza are just a few of the places to visit in and around Santa María. While you're out sightseeing in Oaxaca, be sure to visit other sights like Ex-Convento de Santa Catalina or El Mirador.