Santa Fe de Antioquia

Travel Guide

A historic fountain with water jets, surrounded by lush greenery and a white church with a bell tower in the background.
A street with buildings, a motorcycle, a tricycle, and a mountain in the background.
A vintage-themed living room with a large arched wall, a vintage camera, a red armchair, a wooden cabinet, and a large black and white portrait.
A colorful bus with 'La Santafrenia' written on it parked in front of a building with a tiled roof.
A white tuk-tuk parked on a cobblestone street in a historic town.

Where to stay in Santa Fe de Antioquia

Find the best Santa Fe de Antioquia areas and neighborhoods for the activities you enjoy most.
A narrow street flanked by white buildings with green shutters, a clear sky, and mountains in the background.
Photo by Botak Jon
Open Photo by Botak Jon

Zona Colonial

If you're spending some time in Zona Colonial, Cathedral of Santa Fe de Antioquia and Bolivar Square are top sights worth seeing.

Arde La Selva

Arde La Selva

4 out of 5
km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia
The price is NT$5,556 per night from Sep 10 to Sep 11
NT$5,556
NT$5,556 total
Sep 10 - Sep 11
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo Juan del Corral and Bolivar Square ...
Arde La Selva
Ivanna Hotel Campestre - Santa Fe de Antioquia

Ivanna Hotel Campestre - Santa Fe de Antioquia

4.5 out of 5
Via Anza Vereda, KM 1, Obregon Santa Fe de Antioquia Antioquia
The price is NT$2,323 per night from Sep 15 to Sep 16
NT$2,323
NT$2,323 total
Sep 15 - Sep 16
Book a stay at this luxury hotel in Santa Fe de Antioquia. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Popular attractions Bolivar Square and Cathedral ...
7.6/10 Good! (9 reviews)
"Amazing staff, Swimming pool and spa Hot tub Wonderful area secluded Relaxing atmosphere with all the amenities"

Reviewed on 2026/8/30

Ivanna Hotel Campestre - Santa Fe de Antioquia
Hotel Boutique Al Alma

Hotel Boutique Al Alma

4.5 out of 5
#9-50 Cra. 8 Santa Fe de Antioquia Antioquia
The price is NT$2,846 per night from Sep 20 to Sep 21
NT$2,846
NT$6,377 total
Sep 20 - Sep 21
Book a stay at this luxury hotel in Santa Fe de Antioquia. Enjoy free breakfast, free WiFi, and free beach cabanas. Popular attractions Bolivar Square and Cathedral ...
9.4/10 Exceptional! (64 reviews)
"Great place! Staff was awsone. We had a wonderful time."

Reviewed on 2026/8/10

Hotel Boutique Al Alma
See all 528 properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Finca hotel mi refugio

Finca hotel mi refugio

2 out of 5
1541 Camino real Santa Fé de Antioquia Antioquia
Stay at this cottage in Santa Fe de Antioquia. Enjoy free WiFi, free parking, and a garden. Popular attractions Bolivar Square and Cathedral of Santa Fe de Antioquia ...
Finca hotel mi refugio
SANTA FE DE ANTIOQUIA

SANTA FE DE ANTIOQUIA

2 out of 5
111 Cl. 8 Santa Fe de Antioquia Antioquia
Stay at this aparthotel in Santa Fe de Antioquia. Enjoy free WiFi, 6 outdoor pools, and a garden. Popular attractions Bolivar Square and Cathedral of Santa Fe ...
8/10 Very Good! (1 review)
"Todo Ok"

Reviewed on 2025/2/10

SANTA FE DE ANTIOQUIA
Otalu Suites

Otalu Suites

3 out of 5
Diagonal 80A #45E 09 Medellín Antioquia
Stay at this apartment in Medellín. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Atanasio Giradot Stadium and Botero Plaza ...
Otalu Suites
See all properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Fe de Antioquia attractions

Cathedral of Santa Fe de Antioquia

9.0/10 (28 reviews)
You can learn about the history of Santa Fe de Antioquia with a trip to Cathedral of Santa Fe de Antioquia. Make time to visit the monuments and cathedral while you're in the area.
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