Find Resorts & Hotels with Spas in Santa Ana, CA

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Check availability on Santa Ana Resorts & Hotels with Spas

Our top choices for Santa Ana hotels with a spa

Couples treatment rooms, sauna, steam room, body treatments, body wraps
Hilton Anaheim

Hilton Anaheim

Hilton Anaheim
4.0 star property
Anaheim Resort
8.8 out of 10, Excellent, (452)
"Had a great stay."
United States
Angelina
The price is NT$3,242
NT$3,846 total
includes taxes & fees
Jan 3 - 2026/1/4
Hilton Anaheim
Property amenity
Comfort Inn Anaheim Resort

Comfort Inn Anaheim Resort

Comfort Inn Anaheim Resort
2.5 star property
Anaheim Resort
8.8 out of 10, Excellent, (1032)
"Good and clean room nice staff"
United States
Tan
The price is NT$3,155
NT$4,130 total
includes taxes & fees
Jan 13 - 2026/1/14
Comfort Inn Anaheim Resort
Breakfast, lunch and dinner served
Holiday Inn Diamond Bar - Pomona by IHG

Holiday Inn Diamond Bar - Pomona by IHG

Holiday Inn Diamond Bar - Pomona by IHG
3.0 star property
Diamond Bar
8.8 out of 10, Excellent, (1008)
"Great location, room was great and clean. "
United States
Mynor
The price is NT$3,774
NT$4,310 total
includes taxes & fees
Jan 3 - 2026/1/4
Holiday Inn Diamond Bar - Pomona by IHG
Couples treatment rooms, hot tub, body treatments, aromatherapy
Ayres Hotel & Spa Mission Viejo – Lake Forest

Ayres Hotel & Spa Mission Viejo – Lake Forest

Ayres Hotel & Spa Mission Viejo – Lake Forest
3.5 star property
Mission Viejo
9.2 out of 10, Wonderful, (1010)
"Clean room, helpful staff. Great experience "
United States
Michael
The price is NT$3,712
NT$4,016 total
includes taxes & fees
Dec 15 - Dec 16
Ayres Hotel & Spa Mission Viejo – Lake Forest
Lobby
Brookhurst Plaza Inn

Brookhurst Plaza Inn

Brookhurst Plaza Inn
2.5 star property
Southwest Anaheim
8.2 out of 10, Very Good, (877)
"Really nice and quite! And most important very clean and staff super nice "
United States
Martha M.
Brookhurst Plaza Inn
Lobby
Best Western Plus Newport Mesa Inn

Best Western Plus Newport Mesa Inn

Best Western Plus Newport Mesa Inn
3.0 star property
Costa Mesa
8.8 out of 10, Excellent, (1005)
"Great free breakfast and super quiet. Right near freeway entrance for easy access to basically anywhere you want to go "
United States
Kathryn
The price is NT$3,816
NT$4,235 total
includes taxes & fees
Dec 21 - Dec 22
Best Western Plus Newport Mesa Inn
Interior
Pacific Palms Resort

Pacific Palms Resort

Pacific Palms Resort
4.0 star property
City of Industry
8.8 out of 10, Excellent, (1010)
"Great stay"
United States
Brenda
Pacific Palms Resort
Sauna, body treatments, aromatherapy, body wraps, facials
Marriott's Newport Coast Villas

Marriott's Newport Coast Villas

Marriott's Newport Coast Villas
4.0 star property
Newport Coast
9.0 out of 10, Wonderful, (939)
"Perfect place for the family!"
United States
Doliana
The price is NT$7,923
NT$8,731 total
includes taxes & fees
Jan 4 - 2026/1/5
Marriott's Newport Coast Villas
Sports facility
Hyatt Regency Huntington Beach Resort and Spa

Hyatt Regency Huntington Beach Resort and Spa

Hyatt Regency Huntington Beach Resort and Spa
4.0 star property
Huntington Beach
9.4 out of 10, Exceptional, (1005)
"Wonderful place to stay "
United States
Tina
The price is NT$6,707
NT$9,421 total
includes taxes & fees
Dec 15 - Dec 16
Hyatt Regency Huntington Beach Resort and Spa
Outdoor pool
Casa Laguna Hotel & Spa

Casa Laguna Hotel & Spa

Casa Laguna Hotel & Spa
4.0 star property
Laguna Beach
9.4 out of 10, Exceptional, (935)
"Great small hotel "
United States
David
The price is NT$6,520
NT$7,445 total
includes taxes & fees
Jan 4 - 2026/1/5
Casa Laguna Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Ana Hotel Reviews

Embassy Suites by Hilton Anaheim North

Embassy Suites by Hilton Anaheim North

10/10 Excellent
"We love how spacious the room was but we had an issue with 2 of the pillows in the bedroom had yellow stain on them. We left them on the floor and housekeeping did not pick up or replace them. The shower had a piece that wasn’t attached and was just left there….. other than that we loved the property, free breakfast and arcade and pool! "
Attallah 3-night trip
Posted 20 hours ago
Embassy Suites by Hilton Anaheim North

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Frequently asked questions

Looking for a spa hotel in Santa Ana?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers like the beaches and popular shops in Santa Ana so get ready for a day of fun. Take in the culture at the museums and art galleries during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Santa Ana?
Take in some sights and attractions while you're in Santa Ana by visiting Old Orange County Courthouse, Bowers Museum, and Santa Ana Zoo. If you have a bit of extra time while you're in the area, you might want to check out Discovery Science Center and Heritage Museum of Orange County.
What is a Santa Ana spa hotel?
Spa hotels in Santa Ana provide lodging and have an on-site spa which offers services like therapies as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.