A coastal town with a pier, boats, and a hillside with buildings.

Find Resorts & Hotels with Spas in Pythagorio

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Check availability on Pythagorio Resorts & Hotels with Spas

Tonight
Aug 29 - Aug 30
Tomorrow
Aug 30 - Aug 31
Next weekend
Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13

Our top choices for Pythagorio hotels with a spa

1. Doryssa Theorem Hotel

Doryssa Theorem Hotel
Samos
  • Serene massages await at this eco-certified urban retreat with a steam room and rainfall showers for ultimate relaxation.
NT$3,805
NT$4,535 total
includes taxes & fees
Sep 28 - Sep 29
Doryssa Theorem Hotel

2. Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
  • Rejuvenate at this beachfront hotel with a full-service spa and seaside yoga classes for total relaxation.
NT$5,778
NT$6,879 total
includes taxes & fees
Sep 27 - Sep 28
Doryssa Seaside Resort

3. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
  • Seaside retreat offers rejuvenating spa treatments, private beach access, and indoor-outdoor pools.
NT$6,555
NT$7,735 total
includes taxes & fees
Aug 30 - Aug 31
Proteas Blu Resort - Adults Only

4. Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
  • Indulge in rejuvenating spa treatments at this boutique hotel with seasonal pool and garden oasis.
NT$4,916
NT$5,751 total
includes taxes & fees
Sep 27 - Sep 28
Doryssa Boutique Hotel

5. Casa Cook Samos

Casa Cook Samos
Samos
  • Immerse in a beachfront boutique escape with 4 specialized treatment rooms and daily aromatherapy spa services for complete renewal.
NT$9,076
NT$10,492 total
includes taxes & fees
Sep 29 - Sep 30
Casa Cook Samos

6. Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
  • Revitalize with beachside spa services and seasonal pool at this coastal retreat with Turkish hammam and sauna.
NT$4,866
NT$5,697 total
includes taxes & fees
Sep 2 - Sep 3
Hydrele Beach Hotel

7. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
NT$10,500
NT$12,051 total
includes taxes & fees
Sep 27 - Sep 28
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

8. Armonia Bay Hotel

Armonia Bay Hotel
Samos
  • Mediterranean retreat offers rejuvenating seaside escapes with massages, infinity pools, and garden serenity.
NT$6,587
NT$7,399 total
includes taxes & fees
Sep 19 - Sep 20
Armonia Bay Hotel

9. Aegeon

Aegeon
Samos
  • Unwind at this island hotel with tranquil spa treatments, including massage services in 2 treatment rooms and a relaxing Turkish bath.
NT$2,408
NT$2,821 total
includes taxes & fees
Sep 15 - Sep 16
Aegeon

10. Erato by Samian Mare

Erato by Samian Mare
Samos
  • Discover tranquil waterfront wellness at this eco-certified spa retreat, featuring couples' treatment rooms and traditional Turkish baths.
NT$4,490
NT$5,285 total
includes taxes & fees
Sep 28 - Sep 29
Erato by Samian Mare
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Choose what matters most at spa hotels in Pythagorio

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with pools in Pythagorio

Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
NT$5,778
NT$6,879 total
includes taxes & fees
Sep 27 - Sep 28
Doryssa Seaside Resort

Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
NT$4,866
NT$5,697 total
includes taxes & fees
Sep 2 - Sep 3
Hydrele Beach Hotel

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
NT$6,555
NT$7,735 total
includes taxes & fees
Aug 30 - Aug 31
Proteas Blu Resort - Adults Only

Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
NT$4,916
NT$5,751 total
includes taxes & fees
Sep 27 - Sep 28
Doryssa Boutique Hotel

Casa Cook Samos

Casa Cook Samos
Samos
NT$9,076
NT$10,492 total
includes taxes & fees
Sep 29 - Sep 30
Casa Cook Samos
View all properties

Spa hotels with free breakfast in Pythagorio

Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
NT$5,778
NT$6,879 total
includes taxes & fees
Sep 27 - Sep 28
Doryssa Seaside Resort

Doryssa Theorem Hotel

Doryssa Theorem Hotel
Samos
NT$3,805
NT$4,535 total
includes taxes & fees
Sep 28 - Sep 29
Doryssa Theorem Hotel

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
NT$6,555
NT$7,735 total
includes taxes & fees
Aug 30 - Aug 31
Proteas Blu Resort - Adults Only

Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
NT$4,866
NT$5,697 total
includes taxes & fees
Sep 2 - Sep 3
Hydrele Beach Hotel

Casa Cook Samos

Casa Cook Samos
Samos
NT$9,076
NT$10,492 total
includes taxes & fees
Sep 29 - Sep 30
Casa Cook Samos

Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
NT$4,916
NT$5,751 total
includes taxes & fees
Sep 27 - Sep 28
Doryssa Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pythagorio Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

10/10 Excellent
"Loved this place so much. The pool was excellent, breakfast delicious, restaurants real good and plenty of them for choices. The property is very beautiful. We had the deluxe garden view which I recommend. We only stood 3 nights but I would stay longer next time and one day we took a ferry to Turkey for a day trip to Ephesus which was fantastic. You would need to rent a car if you want to sightsee the island as well."
Christine 3-night trip
Posted 2 weeks ago
Doryssa Seaside Resort
Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

8/10 Good
"Inner architecture is not good, rooms are good and clean, staff are really nice and helpful. I bought sea view room but it was not that much sea view it was more like concrete view, Beach and pool side are quite nice Breakfast was very good"
ercan 1-night trip
Posted 2 weeks ago
Proteas Blu Resort - Adults Only

Frequently asked questions

Looking for a spa hotel in Pythagorio?
Treat yourself to some pampering and book a hotel with a spa. Check out the historical sites and museums in Pythagorio—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Pythagorio?
Casa Cook Samos is a top beach spa hotel featuring a fitness center, a hair salon, a beach bar, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. In-room massages are also available. Other popular spa hotels in Pythagorio include Hydrele Beach Hotel and Proteas Blu Resort - Adults Only.
How many spa hotels are there in Pythagorio?
Among Expedia's 76 accommodation options in Pythagorio, there are 5 spa hotels.
What's there to see and do in Pythagorio?
Take in the sights and attractions that Pythagorio offers with a visit to Samos Pythagorion Archaeological Museum, Pythagoreion, and Glicorisa Beach. If you have extra time while you're in the area, you might want to stop by Folklore Museum of the Nikolaos Dimitriou Foundation of Samos and Tunnel of Eupalinos.
What is a Pythagorio spa hotel?
Spa hotels in Pythagorio feature on-site spas which offer services including therapies and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.