Find Boutique Hotels in Mission District, CA

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Check availability on Mission District Boutique Hotels

Our top choices for Mission District boutique hotels

Berkeley City Club

Berkeley City Club
2.5 star property
Telegraph District
8.8 out of 10, Excellent, (696)
"Wonderful, beautiful, old world hotel, right in the heart of bustling Berkeley. "
United States
Peter
Berkeley City Club

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
Fisherman's Wharf
8.6 out of 10, Excellent, (2337)
"Great decor and really great location"
United States
Jose
The price is NT$4,206
NT$6,063 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Zephyr San Francisco

Hotel Emblem San Francisco

Hotel Emblem San Francisco
4.0 star property
Union Square
9.4 out of 10, Exceptional, (1005)
"Great place to stay when visiting the City - will return again!"
United States
Chris
The price is NT$3,534
NT$5,419 total
includes taxes & fees
Jan 2 - 2026/1/3
Hotel Emblem San Francisco

Inn At Union Square

Inn At Union Square
3.5 star property
Union Square
9.2 out of 10, Wonderful, (1001)
"Everything was perfect location staff room and that continental breakfast was delicious Thankyou "
United Kingdom
robert
The price is NT$3,657
NT$5,091 total
includes taxes & fees
Jan 4 - 2026/1/5
Inn At Union Square

Warwick San Francisco

Warwick San Francisco
4.0 star property
Union Square
8.2 out of 10, Very Good, (1006)
"Room was very nice! Staff was wonderful! "
United States
Brian
The price is NT$3,464
NT$5,227 total
includes taxes & fees
Dec 21 - Dec 22
Warwick San Francisco

The Clancy, Autograph Collection by Marriott

The Clancy, Autograph Collection by Marriott
4.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1001)
"cleanliness,good service, convenient location"
United States
Harry
The price is NT$4,658
NT$6,788 total
includes taxes & fees
Dec 23 - Dec 24
The Clancy, Autograph Collection by Marriott

The Marker Union Square San Francisco

The Marker Union Square San Francisco
4.0 star property
Union Square
9.0 out of 10, Wonderful, (1105)
"Beautiful hotel with very friendly staff!! Location is also very central, walkable to a lot of restaurants. "
United States
Akila
The price is NT$4,397
NT$5,175 total
includes taxes & fees
Dec 23 - Dec 24
The Marker Union Square San Francisco

Argonaut Hotel

Argonaut Hotel
4.5 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (1210)
"Great location, excellent staff."
United States
Walter
The price is NT$6,577
NT$9,075 total
includes taxes & fees
Jan 18 - 2026/1/19
Argonaut Hotel

Palihotel San Francisco

Palihotel San Francisco
3.5 star property
Union Square
8.4 out of 10, Very Good, (626)
"Great vibe here and the rooms and so cute . Excellent bar and bar staff . "
United States
Lana
The price is NT$3,150
NT$4,494 total
includes taxes & fees
Dec 19 - Dec 20
Palihotel San Francisco

The Barnes San Francisco, Tapestry Collection by Hilton

The Barnes San Francisco, Tapestry Collection by Hilton
4.0 star property
Union Square
8.2 out of 10, Very Good, (765)
"Great location, friendly staff."
Canada
Lucy
The price is NT$3,842
NT$4,522 total
includes taxes & fees
Dec 26 - Dec 27
The Barnes San Francisco, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mission District Hotel Reviews

Frequently asked questions

What's there to see and do in Mission District?
The bars is one thing to enjoy while you're in the area. Favorite activities and sights around Mission District include Oracle Park, Pier 39, and San Francisco Bay. Some other things you might want to enjoy include SOMA Pilipinas, SF Armory, and Marsh Theater.
What's the best way to get to my boutique hotel in Mission District?
You have a few options for getting to Mission District. The closest major airport is San Francisco Intl. Airport (SFO), which is located 10 mi (16.1 km) away. You can take advantage of metro transit at 16th Street Mission Station, 24th Street Mission Station, and Right Of Way/20th St Stop.

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