Find hotels near Louisville Science Center, Louisville from NT$2,918

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Compare 1,883 hotels close to Louisville Science Center with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (427)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is NT$5,483
NT$6,451 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Distil, Autograph Collection
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady

The Grady

4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1001)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is NT$5,044
NT$5,935 total
includes taxes & fees
Dec 21 - Dec 22
The Grady
Free daily full breakfast
Market Street Inn

Market Street Inn

3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120)
"I enjoyed my stay, however the breakfast portion was very small even for a petite person like myself, I was still very hungry after breakfast. There was a cleaning issue with the bathroom that was overlooked by the cleaning staff that I alerted the owners to that will hopefully be fixed for future visitors. The house is great and very clean overall. The owners are very nice."
United States
Megan
The price is NT$5,800
NT$6,555 total
includes taxes & fees
Dec 7 - Dec 8
Market Street Inn
Front of property
DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast

3.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.8 out of 10, Exceptional, (95)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is NT$4,472
NT$5,190 total
includes taxes & fees
Dec 7 - Dec 8
DuPont Mansion Bed & Breakfast
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1003)
"Lovely hotel."
United States
Nancy
The price is NT$2,480
NT$2,918 total
includes taxes & fees
Dec 25 - Dec 26
Cambria Hotel Louisville Downtown-Whiskey Row
Exterior
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (1002)
"Very good hotel, staff and location."
United States
Paul
The price is NT$3,231
NT$3,802 total
includes taxes & fees
Dec 15 - Dec 16
Homewood Suites by Hilton Louisville Downtown, KY
Lobby
The Brown Hotel

The Brown Hotel

4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1150)
"I loved everything about this place"
United States
Steven
The Brown Hotel
Signature Suite, 1 Queen Bed, Non Smoking | Premium bedding, down comforters, memory foam beds
Stellar Suites

Stellar Suites

4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
The price is NT$3,694
NT$5,923 total
includes taxes & fees
Jan 1 - 2026/1/2
Stellar Suites
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1000)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is NT$4,352
NT$5,277 total
includes taxes & fees
Jan 1 - 2026/1/2
21c Museum Hotel Louisville
Lobby
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (506)
"Great location"
United States
Tina
The price is NT$3,037
NT$3,573 total
includes taxes & fees
Dec 21 - Dec 22
Towneplace Suites By Marriott Louisville Downtown
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (1699)
"Wonderful property and staff. Would love to stay again. "
United States
Hanna
The price is NT$5,235
NT$6,160 total
includes taxes & fees
Jan 1 - 2026/1/2
Omni Louisville Hotel
Bar (on property)
Moxy Louisville Downtown

Moxy Louisville Downtown

3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (693)
"Awesome location and the staff was super friendly"
United States
Kelly
The price is NT$3,256
NT$3,831 total
includes taxes & fees
Dec 14 - Dec 15
Moxy Louisville Downtown
2 restaurants, breakfast served
Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu

3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (811)
"Love the hotel and will always stay there when visiting "
United States
Jeremy
The price is NT$2,981
NT$3,508 total
includes taxes & fees
Dec 20 - Dec 21
Tempo By Hilton Louisville Downtown Nulu
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (3819)
"10/10 best hotel in Louisville "
United States
James
The price is NT$4,126
NT$4,855 total
includes taxes & fees
Dec 15 - Dec 16
Galt House Hotel Trademark Collection by Wyndham
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1103)
"Clean, hotel was amazing, great breakfast "
United States
Alana
The price is NT$3,482
NT$4,098 total
includes taxes & fees
Dec 29 - Dec 30
Embassy Suites Louisville Downtown
View from room
Aloft Louisville Downtown

Aloft Louisville Downtown

3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.0 out of 10, Wonderful, (1001)
"The first night our lock on our door stopped working, so we were locked out. They were very accommodating to get us a different room for the evening and got us whatever we needed! Very nice place to stay downtown!"
United States
Chris
The price is NT$3,029
NT$3,564 total
includes taxes & fees
Dec 19 - Dec 20
Aloft Louisville Downtown
Property amenity
AC Hotel Louisville Downtown

AC Hotel Louisville Downtown

3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (595)
"Loved the Hotel and area around the Hotel. Great shopping and restaurants"
United States
Melissa
The price is NT$2,951
NT$3,472 total
includes taxes & fees
Dec 26 - Dec 27
AC Hotel Louisville Downtown
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

4.0 star property
Old Louisville, 3 km from Louisville Science Center
9.4 out of 10, Exceptional, (56)
"The room was beautiful, breakfast was delicious and the park across the street was lovely. I especially enjoyed having coffee on the back veranda."
United States
Cher
The price is NT$4,245
NT$4,927 total
includes taxes & fees
Dec 7 - Dec 8
Central Park Bed & Breakfast
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1012)
"Nice hotel and rooms. "
United States
James
The price is NT$4,231
NT$4,979 total
includes taxes & fees
Dec 7 - Dec 8
Hotel Genevieve part of JdV by Hyatt
Restaurant
Louisville Marriott Downtown

Louisville Marriott Downtown

4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1000)
"Room was great, but the service by the attendant that wait on me was exceptional in what she done for me."
United States
Michael
The price is NT$5,358
NT$6,304 total
includes taxes & fees
Dec 19 - Dec 20
Louisville Marriott Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Louisville Science Center Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"Everything good"
Israel 1-night trip
Posted 15 hours ago
Galt House Hotel Trademark Collection by Wyndham

Hotels near other Louisville Science Center attractions

Exploration of Louisville Slugger Museum in Downtown Louisville, Kentucky on a Sunny Day

Louisville Slugger Museum

4.5/5 (1,200 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
See properties
A great stop! This has to be one of the best museums I’ve been about somebody! Great stop and a fantastic life!
Photo by Corey Dargan
Open Photo by Corey Dargan

Muhammad Ali Center

4.3/5 (298 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
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Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 291 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 291 hotels and other accommodations within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.
Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?
For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse.

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