The Best Hotels Closest to Lexington Medical Center in West Columbia for 2026

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Our top choices for Lexington Medical Center hotels

An outdoor patio with a brick barbecue, wicker furniture, and string lights.

1. Residence Inn Columbia West/Lexington

0.4 km from Lexington Medical Center

Bruce E

NT$4,181 total

includes taxes & fees

Dec 3 - Dec 4

An outdoor patio with wicker furniture, a central fire pit, and red umbrellas.

2. TownePlace Suites Columbia West/Lexington

0.5 km from Lexington Medical Center

Michael

NT$4,188 total

includes taxes & fees

Dec 5 - Dec 6

A patio area with wicker furniture, a central fire pit, and outdoor umbrellas.

3. Hilton Garden Inn Columbia Airport

0.5 km from Lexington Medical Center

SHERI

NT$3,602 total

includes taxes & fees

Nov 26 - Nov 27

A modern building entrance with a brick pathway leading to a glass door.

4. Hampton Inn Columbia-I-26 Airport

0.7 km from Lexington Medical Center

Vicky

NT$3,144 total

includes taxes & fees

Dec 5 - Dec 6

A hotel lobby with a brown sofa, a small table, a refrigerator stocked with snacks, a staircase with a green wall, and a dining area in the background.

5. Sleep Inn Columbia

2.8 km from Lexington Medical Center

Emily

NT$2,662 total

includes taxes & fees

Nov 26 - Nov 27

A spacious lobby with a high ceiling, a staircase, a large sofa, a coffee table, and a TV mounted on the wall.

6. Doubletree by Hilton Columbia, SC

3 km from Lexington Medical Center

Donna

NT$3,212 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a sofa, a small table, a bed, and a painting on the wall.

7. Best Western Executive Inn & Suites

2.6 km from Lexington Medical Center

Toyia

NT$3,871 total

includes taxes & fees

Nov 9 - Nov 10

A hotel reception desk with a 'Comfort Inn' sign, a digital screen, and a 'Welcome' mat.

8. Comfort Inn Columbia West

2.9 km from Lexington Medical Center

Cornelius

NT$2,764 total

includes taxes & fees

Dec 1 - Dec 2

A reception area with a stone mosaic wall, a wooden reception desk, and a counter with a green top. There are framed certificates on the wall and a vending machine to the right.

9. Quality Inn Columbia Airport

2.8 km from Lexington Medical Center

Jmesha

NT$2,213 total

includes taxes & fees

Dec 3 - Dec 4

A living room with a sofa, chairs, a coffee table, a TV, and a radiator.

10. Knights Inn Columbia

2.6 km from Lexington Medical Center

Raheeam

NT$2,815 total

includes taxes & fees

Nov 17 - Nov 18

A spacious lobby with a tiled floor, striped armchairs, a blue ottoman, and a flat-screen TV mounted on a stone wall.

11. Clarion Inn Columbia Airport

2.7 km from Lexington Medical Center

Sheneke

NT$1,820 total

includes taxes & fees

Nov 10 - Nov 11

A hotel room with two beds, a desk with a computer, a chair, and a view of the outdoors.

12. Baymont by Wyndham Columbia Northwest

3 km from Lexington Medical Center

Latoya

NT$2,463 total

includes taxes & fees

Nov 8 - Nov 9

A modern living room with a grey sofa, a coffee table, and a dining area with a table and chairs.

13. Columbia Duet Unit B

2.9 km from Lexington Medical Center

NT$27,915 total

includes taxes & fees

Nov 9 - Nov 10

A dining area with a wooden table, chairs, and a lamp. There is a plant on a shelf and a TV mounted on the wall.

14. Columbia Duet - 2 Units

2.9 km from Lexington Medical Center

NT$47,137 total

includes taxes & fees

Nov 9 - Nov 10

A spacious indoor area with a long table, multiple chairs, and a seating area with sofas and a TV.

15. The Lantern Hotel Columbia

7.2 km from Lexington Medical Center

Nichole

NT$5,118 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel lobby with a large dining table, multiple seating areas, and a large screen wall.

16. Hampton Inn & Suites Lexington Columbia

5.5 km from Lexington Medical Center

Jean

NT$4,150 total

includes taxes & fees

Nov 28 - Nov 29

An outdoor patio with a bar area, seating, and a grill station.

17. Tru By Hilton Columbia Downtown

6.3 km from Lexington Medical Center

Jennifer

NT$3,561 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor patio with a stone fire pit, seating, and a covered area with lights.

18. Springhill Suites by Marriott Columbia near Fort Jackson

15.4 km from Lexington Medical Center

Leslie

NT$3,500 total

includes taxes & fees

Nov 22 - Nov 23

A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.

19. Hotel Trundle

7.2 km from Lexington Medical Center

Michale

NT$6,161 total

includes taxes & fees

Nov 10 - Nov 11

A modern hotel room with a large bed, a seating area, and a TV.

20. Homewood Suites By Hilton Columbia Downtown

6.3 km from Lexington Medical Center

Brian

NT$4,159 total

includes taxes & fees

Nov 23 - Nov 24

View all properties

Compare popular hotels close to Lexington Medical Center

Property	Property class	Guest rating
Residence Inn Columbia West/Lexington	3.0 star property	9.2 Wonderful 431 reviews	View
TownePlace Suites Columbia West/Lexington	3.0 star property	9.2 Wonderful 512 reviews	View
Hilton Garden Inn Columbia Airport	3.0 star property	9.0 Wonderful 1,003 reviews	View
Hampton Inn Columbia-I-26 Airport	2.5 star property	8.2 Very good 1,002 reviews	View
Sleep Inn Columbia	2.5 star property	8.2 Very good 1,218 reviews	View

Top Lexington Medical Center Hotel Reviews

The Lantern Hotel Columbia

Downtown Columbia

10/10 Excellent

Monica

Hampton Inn & Suites Lexington Columbia

Lexington

10/10 Excellent

Jodi

Hotel Trundle

Downtown Columbia

10/10 Excellent

Loretta

Residence Inn Columbia West/Lexington

West Columbia

10/10 Excellent

Anthony

A two-story house with a porch, a small balcony, and a gabled roof.

The 1425 Inn

Downtown Columbia

10/10 Excellent

I needed a place to stay close by to the hospital while my husband had surgery, but wanted a warm comfortable place. The place was just what I needed. Shanna was warm and welcoming, and couldn't have done more to make my stay a good one. I felt very much at home. The inn was beautifully decorated and well kept. Breakfast was excellent and there were snacks available at all times, a plus after a long day at the hospital. I would highly recommend this place.

Phoebe A

Tru By Hilton Columbia Downtown

Downtown Columbia

10/10 Excellent

Hynrie Emerlou

A modern bar area with a central island, bar stools, and a television.

Cambria Hotel Columbia Downtown The Vista

Downtown Columbia

10/10 Excellent

Carla

A spacious lobby with a high ceiling, a central seating area with a patterned rug, and a fireplace.

Holiday Inn Express Columbia West - Lexington by IHG

Lexington

10/10 Excellent

Casi

A building entrance with a stone facade, large glass doors, and a wooden archway.

Staybridge Suites Columbia by IHG

Downtown Columbia

10/10 Excellent

We have a child at the university and stayed here for a weekend visit. I had never been, but my husband had stayed years ago for a swim meet. He insisted I book here, though I wanted to stay at the Hilton. I was so pleasantly surprised when I arrived at the Staybridge! The staff was super friendly, and exceptionally efficient. The room was very spacious, and the little kitchen was perfect! The included breakfast was also excellent. I will stay here every visit to Columbia!

Karen

A hotel with a modern exterior, featuring a brick facade, large windows, and a well-lit outdoor area with palm trees and a landscaped garden.

Holiday Inn Express & Suites Lexington by IHG

Downtown Lexington

10/10 Excellent

Warning: I’ll be naming names in this review. To say that I was impressed is the understatement of the year! I am every hotels worst nightmare when it comes to my level of pickiness as a guest because I check everywhere. Well, this hotel beat me to the punch! Room 113 was so clean that we booked a second night just to extend our stay there. Sindy was responsible for cleaning my room so I found her and asked how she got it so clean. When she told me the entire cleaning staff uses black...

Jacqueline

Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

10/10 Excellent

Savannah

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and trees.

Residence Inn by Marriott Columbia Northwest/Harbison

Irmo

10/10 Excellent

Samantha

An outdoor patio with yellow chairs and tables, a pergola with string lights, and a stone wall.

Home2 Suites by Hilton Columbia Southeast Fort Jackson

Columbia

10/10 Excellent

Jodi

Frequently Asked Questions

What's the area like around Lexington Medical Center?

Lexington Medical Center is located in West Columbia. Travelers like the surrounding area for its bars. If you're looking for a convenient place to stay, check out the 15 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Lexington Medical Center?

Adjacent to Lexington Medical Center, Hilton Garden Inn Columbia Airport is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. Other good options close by include Hampton Inn Columbia-I-26 Airport and Residence Inn Columbia West/Lexington.

How many hotels are there near Lexington Medical Center?

Expedia has 15 hotels and other accommodations within a mile from Lexington Medical Center.

If I need to cancel the hotel reservation for my stay near Lexington Medical Center, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view top deals close to Lexington Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Lexington Medical Center?

For more details about changing or cancelling your stay near Lexington Medical Center, head over to our customer service page.

What can I see and do near Lexington Medical Center?

Study the collections at South Carolina State Museum, Columbia Museum of Art, or Robert Mills Historic House and Park. While you're exploring, swing by First Baptist Church, South Carolina State House, and Imara Woman to learn a bit about the area. You can check out the local talent at Koger Center for the Arts, Township Auditorium, and Town Theatre.

Find hotels near Lexington Medical Center, West Columbia from NT$2,049

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Treat yourself

Be picky

Check prices for these dates

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Property class

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Our top choices for Lexington Medical Center hotels

1. Residence Inn Columbia West/Lexington

2. TownePlace Suites Columbia West/Lexington

3. Hilton Garden Inn Columbia Airport

4. Hampton Inn Columbia-I-26 Airport

5. Sleep Inn Columbia

6. Doubletree by Hilton Columbia, SC

7. Best Western Executive Inn & Suites

8. Comfort Inn Columbia West

9. Quality Inn Columbia Airport

10. Knights Inn Columbia

11. Clarion Inn Columbia Airport

12. Baymont by Wyndham Columbia Northwest

13. Columbia Duet Unit B

14. Columbia Duet - 2 Units

15. The Lantern Hotel Columbia

16. Hampton Inn & Suites Lexington Columbia

17. Tru By Hilton Columbia Downtown

18. Springhill Suites by Marriott Columbia near Fort Jackson

19. Hotel Trundle

20. Homewood Suites By Hilton Columbia Downtown

Compare popular hotels close to Lexington Medical Center

Top Lexington Medical Center Hotel Reviews

The Lantern Hotel Columbia

10/10 Excellent

Frequently Asked Questions

What's the area like around Lexington Medical Center?

What's the best hotel to stay near Lexington Medical Center?

How many hotels are there near Lexington Medical Center?

If I need to cancel the hotel reservation for my stay near Lexington Medical Center, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Lexington Medical Center?

What can I see and do near Lexington Medical Center?