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Our top choices for Lexington Medical Center hotels

A hotel room with a bed, a desk with a computer, a nightstand, a lamp, and a window with curtains.
A compact kitchen with a dishwasher, a refrigerator, and a coffee maker.
A corridor with refrigerated beverage dispensers and snack shelves.

1. Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington
0.4 km from Lexington Medical Center
United States
Cierra
NT$4,207
NT$4,544 total
includes taxes & fees
Sep 20 - Sep 21
Residence Inn Columbia West/Lexington
An outdoor patio area with wicker furniture, a circular fire pit, and umbrellas.
A row of treadmills in a gym with large windows and a sign about safety rules.
A compact kitchen with a microwave, dishwasher, and refrigerator.
A hotel with outdoor pool, lounge chairs, and umbrellas.

2. TownePlace Suites Columbia West/Lexington

TownePlace Suites Columbia West/Lexington
0.5 km from Lexington Medical Center
United States
mario
NT$3,984
NT$4,303 total
includes taxes & fees
Oct 11 - Oct 12
TownePlace Suites Columbia West/Lexington
A patio area with wicker furniture, a central fire pit, and outdoor umbrellas.
A modern bar area with a marble countertop, multiple bar stools, and a large flat-screen TV mounted on the wall.
A modern kitchen with a central island, bar stools, and a coffee station with various containers.
A spacious lobby with a large seating area, a coffee table, and a potted plant.

3. Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport
0.5 km from Lexington Medical Center
United States
Russell
NT$3,633
NT$3,923 total
includes taxes & fees
Sep 27 - Sep 28
Hilton Garden Inn Columbia Airport
A modern building entrance with a brick pathway leading to a glass door.
A modern kitchen with a central island, bar stools, and a dining area with tables and chairs.
A snack display with various chips and packaged snacks.
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

4. Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport
0.7 km from Lexington Medical Center
United States
Vicky
NT$3,110
NT$3,431 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn Columbia-I-26 Airport
A hotel lobby with a brown sofa, a small table, a refrigerator stocked with snacks, a staircase with a green wall, and a dining area in the background.
A hotel room with a bed, a desk with a TV, a chair, and a mirror.
A restaurant with wooden tables and chairs, a counter with a coffee machine, and a TV mounted on the wall.
A reception area with a wooden reception desk, a sign reading "Sleep Inn," and a green wall with a decorative leaf pattern.

5. Sleep Inn Columbia

Sleep Inn Columbia
2.8 km from Lexington Medical Center
United States
Kristine
NT$2,682
NT$2,896 total
includes taxes & fees
Oct 6 - Oct 7
Sleep Inn Columbia
A spacious lobby with a high ceiling, a staircase, a large sofa, a coffee table, and a TV mounted on the wall.
A hotel room with two beds, a large mirror, a vanity with a sink, and a towel rack.
A bar area with a television, red bar stools, and a red carpeted floor.
A hotel with a swimming pool, outdoor seating, and a modern architectural design.

6. Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC
3 km from Lexington Medical Center
United States
Alma
NT$3,110
NT$3,431 total
includes taxes & fees
Sep 27 - Sep 28
Doubletree by Hilton Columbia, SC
A hotel room with a sofa, a small table, a bed, and a painting on the wall.
A modern hotel lobby with seating, a coffee station, and a dining area.
A gym with treadmills, elliptical machines, and stationary bikes.
A reception area with a large 'SOUTH CAROLINA' sign, a reception desk, and a seating area with chairs.

7. Best Western Executive Inn & Suites

Best Western Executive Inn & Suites
2.6 km from Lexington Medical Center
United States
Cecilia
NT$3,824
NT$4,130 total
includes taxes & fees
Sep 17 - Sep 18
Best Western Executive Inn & Suites
A hotel reception desk with a 'Comfort Inn' sign, a digital screen, and a 'Welcome' mat.
A Comfort Inn hotel with a clear entrance, multiple floors, and a parking lot.
A hotel lobby with seating areas, a bar, and a kitchen in the background.
A spacious restaurant with multiple dining areas, a kitchen in the background, and a flat-screen TV mounted on the wall.

8. Comfort Inn Columbia West

Comfort Inn Columbia West
2.9 km from Lexington Medical Center
United States
Tatyana
NT$2,404
NT$2,692 total
includes taxes & fees
Sep 27 - Sep 28
Comfort Inn Columbia West
A reception area with a stone mosaic wall, a wooden reception desk, and a counter with a green top. There are framed certificates on the wall and a vending machine to the right.
A living room with a fireplace, two armchairs, a sofa, a flat-screen TV, and a ceiling-mounted air conditioning unit.
A hotel with a brick facade, a covered entrance, and a sign for Quality Inn.
A bathroom with a granite sink, a large mirror, a shower with a glass door, and a towel rack.

9. Quality Inn Columbia Airport

Quality Inn Columbia Airport
2.8 km from Lexington Medical Center
United States
Sarah
NT$2,004
NT$2,165 total
includes taxes & fees
Oct 15 - Oct 16
Quality Inn Columbia Airport
A hotel room with a bed, desk, chair, and a painting on the wall.
A bathroom with a bathtub, toilet, and shower.
A hotel room with a bed, a wooden dresser, a black refrigerator, a white microwave, a television mounted on the wall, and a trash can.
A motel with a central corridor and individual rooms on either side.

10. Executive Inn

Executive Inn
0.5 km from Lexington Medical Center
United States
gaylene
NT$1,822
NT$1,968 total
includes taxes & fees
Sep 20 - Sep 21
Executive Inn
A living room with a sofa, chairs, a coffee table, a TV, and a radiator.
A hotel room with a bed, a sofa, a desk, and a TV.
A Knights Inn with a stone facade, a red awning, and a signboard.
A spacious living area with a high ceiling, a dining table with chairs, a sofa, and a large plant.

11. Knights Inn Columbia

Knights Inn Columbia
2.6 km from Lexington Medical Center
United States
Jeffrey
NT$2,550
NT$2,754 total
includes taxes & fees
Sep 17 - Sep 18
Knights Inn Columbia
A bar area with wooden chairs, a counter with a computer, and a seating area with a sofa and chairs.
A hotel room with a bed, bedside lamps, a nightstand, and a bathtub.
A lobby with a tiled floor, seating area with chairs and ottomans, a stone accent wall with a flat-screen TV, and a door marked "EXIT".
A restaurant with wooden chairs and tables, a bar area with a minibar, and a seating area with a sofa and cushions.

12. Clarion Inn Columbia Airport

Clarion Inn Columbia Airport
2.7 km from Lexington Medical Center
United States
Kelsy
NT$1,906
NT$2,059 total
includes taxes & fees
Sep 27 - Sep 28
Clarion Inn Columbia Airport
A hotel room with two beds, a desk with a computer, a chair, and a view of the outdoors.
A hotel fitness center with treadmills, elliptical machines, and a weight rack.
A hotel room with a desk, two armchairs, a sofa, a television, a coffee maker, and a mirror.
A breakfast counter with a clock, a sign for breakfast corner, and various food and drink dispensers.

13. Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest
3 km from Lexington Medical Center
United States
Asmaa
NT$1,880
NT$2,031 total
includes taxes & fees
Sep 21 - Sep 22
Baymont by Wyndham Columbia Northwest
A swimming pool with two lanes, surrounded by lounge chairs and a fence.
A hotel room with two beds, a chair, a nightstand, and a lamp.
A hotel lobby with a reception desk, a leather sofa, a TV mounted on the wall, and a marble floor.
A breakfast counter with a sign reading "Daybreak Breakfast," a coffee machine, a syrup dispenser, and a display of cereal boxes.

14. Days Inn by Wyndham Columbia

Days Inn by Wyndham Columbia
2.8 km from Lexington Medical Center
United States
Kyle
NT$1,869
NT$2,094 total
includes taxes & fees
Sep 20 - Sep 21
Days Inn by Wyndham Columbia
A modern living room with a grey sofa, a coffee table, and a dining area with a table and chairs.
A hotel room with two single beds, a window with blinds, a wall-mounted artwork, and a nightstand with a lamp.
A wooden deck with wicker furniture, including two chairs and a sofa, surrounded by lush greenery.
A modern kitchen with white cabinetry, a built-in dishwasher, and a large island.

15. Columbia Duet Unit B

Columbia Duet Unit B
2.9 km from Lexington Medical Center
NT$6,017
NT$27,365 total
includes taxes & fees
Sep 21 - Sep 22
Columbia Duet Unit B
A dining area with a wooden table, chairs, and a lamp. There is a plant on a shelf and a TV mounted on the wall.
A modern kitchen with white cabinetry, a dishwasher, a coffee maker, and a window with blinds.
A living room with a sofa, armchair, coffee table, fireplace, TV, and a dining area in the background.
A neatly arranged bedroom with a large bed, a window with curtains, a bedside table with a lamp, and a mirror on the wall.

16. Columbia Duet - 2 Units

Columbia Duet - 2 Units
2.9 km from Lexington Medical Center
NT$11,170
NT$46,188 total
includes taxes & fees
Sep 21 - Sep 22
Columbia Duet - 2 Units
A spacious indoor area with a long table, multiple chairs, and a seating area with sofas and a TV.
A spacious lobby with modern furniture, a decorative partition, and a visible kitchen area.
A modern building with a brick facade, large windows, and outdoor exercise equipment.
A modern living room with a fireplace, comfortable seating, and large windows.

17. The Lantern Hotel Columbia

The Lantern Hotel Columbia
7.2 km from Lexington Medical Center
United States
Kevin
NT$5,020
NT$5,622 total
includes taxes & fees
Sep 27 - Sep 28
The Lantern Hotel Columbia
A modern hotel lobby with a large dining table, multiple seating areas, and a large screen wall.
A hotel room with a bed, desk, chair, air conditioning unit, and a window with a view of trees.
A modern kitchen area with a long counter, various food items, and a chalkboard with food-related drawings.
A reception desk with a "Welcome to the Palmetto State" sign, a wooden accent wall, a minibar, and a digital kiosk.

18. Hampton Inn & Suites Lexington Columbia

Hampton Inn & Suites Lexington Columbia
5.5 km from Lexington Medical Center
United States
LISA
NT$3,782
NT$4,199 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn & Suites Lexington Columbia
A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.
Two people celebrating with confetti in a bar setting.
A hotel room with exposed brick walls, a large bed, a desk with a telephone, and a television on the wall.
A hotel named 'Hotel Trundle' with a brick facade, American and another flag, and potted plants in front.

19. Hotel Trundle

Hotel Trundle
7.2 km from Lexington Medical Center
United States
Anthony
NT$5,092
NT$5,704 total
includes taxes & fees
Sep 30 - Oct 1
Hotel Trundle
A modern bar area with a long counter, multiple bar stools, and a decorative wall with geometric patterns.
A multi-story hotel with a modern design, featuring a mix of brick and glass facades, and a prominent entrance with a covered walkway.
An outdoor patio with a bar area, seating, and a grill station.
A modern lounge area with a sectional sofa, two armchairs, a coffee table, and a wall-mounted TV.

20. Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown
6.3 km from Lexington Medical Center
United States
Laurel
NT$3,110
NT$3,483 total
includes taxes & fees
Sep 27 - Sep 28
Tru By Hilton Columbia Downtown
View all properties

Compare popular hotels close to Lexington Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Residence Inn Columbia West/Lexington
9.2
Wonderful
418 reviews
View
An outdoor patio area with wicker furniture, a circular fire pit, and umbrellas.
TownePlace Suites Columbia West/Lexington
9.2
Wonderful
502 reviews
View
A patio area with wicker furniture, a central fire pit, and outdoor umbrellas.
Hilton Garden Inn Columbia Airport
9.0
Wonderful
1,000 reviews
View
A modern building entrance with a brick pathway leading to a glass door.
Hampton Inn Columbia-I-26 Airport
8.2
Very good
1,003 reviews
View
A hotel lobby with a brown sofa, a small table, a refrigerator stocked with snacks, a staircase with a green wall, and a dining area in the background.
Sleep Inn Columbia
8.2
Very good
1,181 reviews
View

Top Lexington Medical Center Hotel Reviews

Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

10/10 Excellent
"I slept unusually well at this hotel. It was quiet, clean and well maintained. No issues with the property and it’s in a great location."
Tamika 2-night trip
Posted 3 hours ago
Doubletree by Hilton Columbia, SC
Lexington Expo Hotel by IHG

Lexington Expo Hotel by IHG

10/10 Excellent
"Great Hotel"
Brian 6-night trip
Posted 1 day ago
Lexington Expo Hotel by IHG
Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington

10/10 Excellent
"Parking was easy. Room was extremely clean and the bed was comfy."
Cierra 1-night trip
Posted 3 days ago
Residence Inn Columbia West/Lexington
Executive Inn

Executive Inn

8/10 Good
"Serviceable for a quick overnight"
John 2-night trip
Posted 3 days ago
Executive Inn
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

8/10 Good
"Everything was as it should be."
Brenda G 1-night trip
Posted 3 days ago
Hampton Inn Columbia-I-26 Airport
Best Western Executive Inn & Suites

Best Western Executive Inn & Suites

8/10 Good
"Great visit"
Jody 1-night trip
Posted 1 month ago
Best Western Executive Inn & Suites
TownePlace Suites Columbia West/Lexington

TownePlace Suites Columbia West/Lexington

10/10 Excellent
"Great space, well kept property."
mario 1-night trip
Posted 1 month ago
TownePlace Suites Columbia West/Lexington
Knights Inn Columbia

Knights Inn Columbia

10/10 Excellent
"Kool"
Jeffrey 2-night trip
Posted 2 months ago
Knights Inn Columbia

Frequently asked questions

What's the area like around Lexington Medical Center?
Lexington Medical Center is located in West Columbia. Travelers like the surrounding area for its bars. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Lexington Medical Center?
Adjacent to Lexington Medical Center, Hilton Garden Inn Columbia Airport is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. Other good options close by include Hampton Inn Columbia-I-26 Airport and Residence Inn Columbia West/Lexington.
How many hotels are there near Lexington Medical Center?
Expedia has 18 hotels and other accommodations within a mile from Lexington Medical Center.
If I need to cancel the hotel reservation for my stay near Lexington Medical Center, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view top deals close to Lexington Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Lexington Medical Center?
For more details about changing or cancelling your stay near Lexington Medical Center, head over to our customer service page.
What can I see and do near Lexington Medical Center?
Study the collections at South Carolina State Museum, Columbia Museum of Art, or Robert Mills Historic House and Park. While you're exploring, swing by First Baptist Church, South Carolina State House, and Hampton-Preston Mansion and Gardens to learn a bit about the area. You can check out the local talent at Koger Center for the Arts, Township Auditorium, and Columbia Marionette Theater.