Find hotels in Isle of Palms South, Jacksonville from NT$1,907

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Discover 2,952 Isle of Palms South hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham Garden Jacksonville

3.0 star property
15.3 km from Isle of Palms South
7.8 out of 10, Good, (1790)
"Room was great, clean and staff we're friendly!"
United States
David
The price is NT$2,188
NT$2,483 total
includes taxes & fees
Dec 7 - Dec 8
Wyndham Garden Jacksonville

Days Inn by Wyndham Orange Park/Jacksonville

2.0 star property
27.6 km from Isle of Palms South
7.6 out of 10, Good, (1007)
"Friendly and courteous staff, clean room, very good dining options around."
United States
Ben Jasad
The price is NT$2,055
NT$2,311 total
includes taxes & fees
Dec 3 - Dec 4
Days Inn by Wyndham Orange Park/Jacksonville

WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk

2.0 star property
12.3 km from Isle of Palms South
8.8 out of 10, Excellent, (740)
"Room was really clean and relaxing. "
United States
Tracey Frink
The price is NT$3,976
NT$4,512 total
includes taxes & fees
Dec 8 - Dec 9
WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk

San Marco Inn East

3.0 star property
19.5 km from Isle of Palms South
8.4 out of 10, Very Good, (1250)
"Great location"
United States
Walter
The price is NT$1,680
NT$1,907 total
includes taxes & fees
Dec 8 - Dec 9
San Marco Inn East

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

3.0 star property
21.1 km from Isle of Palms South
7.4 out of 10, Good, (353)
"Clean room, nice staff "
United States
Dalsi
The price is NT$2,295
NT$2,605 total
includes taxes & fees
Dec 4 - Dec 5
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

DoubleTree by Hilton Hotel Jacksonville Riverfront

4.0 star property
22.2 km from Isle of Palms South
6.8 out of 10, (1464)
"Loved the hotel "
United States
lucy
The price is NT$3,475
NT$3,944 total
includes taxes & fees
Dec 21 - Dec 22
DoubleTree by Hilton Hotel Jacksonville Riverfront

WoodSpring Suites Jacksonville - South

2.5 star property
15.9 km from Isle of Palms South
7.6 out of 10, Good, (636)
"Always good stay. "
United States
Errol
The price is NT$2,009
NT$2,280 total
includes taxes & fees
Dec 7 - Dec 8
WoodSpring Suites Jacksonville - South

Residence Inn by Marriott Jacksonville Butler Boulevard

3.0 star property
10.8 km from Isle of Palms South
8.8 out of 10, Excellent, (1008)
"Very nice and less than ten minutes from shops and food. "
United States
William
The price is NT$2,982
NT$3,385 total
includes taxes & fees
Dec 7 - Dec 8
Residence Inn by Marriott Jacksonville Butler Boulevard

Hyatt Regency Jacksonville

4.0 star property
22.1 km from Isle of Palms South
9.0 out of 10, Wonderful, (1391)
"We had an amazing stay! A shout out to Yancy at the front desk who was such a great help for my family and I! "
United States
Jameyra
The price is NT$4,520
NT$5,182 total
includes taxes & fees
Dec 19 - Dec 20
Hyatt Regency Jacksonville

Hotel Indigo Jacksonville-Deerwood Park by IHG

3.5 star property
11.6 km from Isle of Palms South
9.2 out of 10, Wonderful, (1005)
"Very nice stay "
United States
Timmothy
The price is NT$3,491
NT$3,962 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Indigo Jacksonville-Deerwood Park by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
3.8 km from Isle of Palms South
8.6 out of 10, Excellent, (1016)
"We enjoyed the stay."
United States
Kenny
The price is NT$3,114
NT$3,534 total
includes taxes & fees
Dec 5 - Dec 6
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Southbank Hotel by Marriott Jacksonville Riverwalk

3.5 star property
21.9 km from Isle of Palms South
8.2 out of 10, Very Good, (1617)
"We liked our stay"
United States
Lorie
The price is NT$3,079
NT$3,495 total
includes taxes & fees
Jan 1 - 2026/1/2
Southbank Hotel by Marriott Jacksonville Riverwalk

Hilton Jacksonville At Mayo Clinic

4.5 star property
1.9 km from Isle of Palms South
9.6 out of 10, Exceptional, (44)
"Beautiful hotel. Close to Mayo Clinic."
United States
Patty
The price is NT$3,742
NT$4,247 total
includes taxes & fees
Dec 24 - Dec 25
Hilton Jacksonville At Mayo Clinic

Candlewood Suites Jacksonville Southpoint by IHG

2.5 star property
16.2 km from Isle of Palms South
9.0 out of 10, Wonderful, (280)
"Had a good stay ! "
United States
Martiyanna
The price is NT$2,863
NT$3,249 total
includes taxes & fees
Dec 4 - Dec 5
Candlewood Suites Jacksonville Southpoint by IHG

Comfort Suites Baymeadows Near Butler Blvd

3.0 star property
14.3 km from Isle of Palms South
8.2 out of 10, Very Good, (1031)
"Enjoyed our stay! Staff was awesome....very clean and quiet stay."
United States
Rita
The price is NT$3,082
NT$3,498 total
includes taxes & fees
Dec 17 - Dec 18
Comfort Suites Baymeadows Near Butler Blvd

Margaritaville Jacksonville Beach

2.5 star property
4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (3415)
"I had a great weekend stay on my birthday! "
United States
Adrian
Margaritaville Jacksonville Beach

Delta Hotels by Marriott™ Jacksonville Deerwood

4.0 star property
15.2 km from Isle of Palms South
8.6 out of 10, Excellent, (458)
"Loved our stay, staff were nice and hotel was clean. "
United States
Wilfredo
The price is NT$2,908
NT$3,301 total
includes taxes & fees
Dec 21 - Dec 22
Delta Hotels by Marriott™ Jacksonville Deerwood

Rodeway Inn

2.0 star property
27.7 km from Isle of Palms South
8.0 out of 10, Very Good, (111)
"Good Hotel."
Mexico
Jose
The price is NT$2,088
NT$2,348 total
includes taxes & fees
Dec 3 - Dec 4
Rodeway Inn

Hampton Inn & Suites Jacksonville Deerwood Park

2.5 star property
11.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (1009)
"Great stay"
United States
Mary Jean
The price is NT$3,240
NT$3,677 total
includes taxes & fees
Dec 7 - Dec 8
Hampton Inn & Suites Jacksonville Deerwood Park

Tricove Inn & Suites

2.5 star property
15.7 km from Isle of Palms South
7.2 out of 10, Good, (1004)
"disgusting over priced mildew and mold smell, handle to shower broken and dangerous, doors didnt close without force, lamp flickering and barely working - very upset i got charged 120 dollars for this low quality nasty dangerous room and will be filing a complaint with whatever bureau over sees them"
United States
Robin
The price is NT$2,354
NT$2,672 total
includes taxes & fees
Dec 3 - Dec 4
Tricove Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms South

Find the best Isle of Palms South areas and neighborhoods for the activities you enjoy most.

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Southside

If you're spending some time in Southside, St. Johns Town Center and Merill Road Shopping Center are top sights worth seeing.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Northwest

If you're spending some time in Northwest, Cummer Museum of Art and Gardens and Jacksonville-Baldwin Rail Trail are top sights worth seeing.

Top Isle of Palms South Hotel Reviews

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Frequently asked questions

What is Isle of Palms South like?
Travelers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighborhood.
How many hotels will I be able to find in Isle of Palms South?
Expedia has 7 Isle of Palms South hotels and other accommodations, and one might make a good home base for venturing out into the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view top deals in Isle of Palms South.
Where can I learn more about changing or cancelling my trip to Isle of Palms South?
To find more details about changing or cancelling your trip to Isle of Palms South, go to https://www.expedia.com/service/.
What are the top things to see and do in Isle of Palms South?
Adventure Landing, Cradle Creek Preserve, and Windsor Parke Golf Club are just a few of the places to visit in and around Isle of Palms South. Jacksonville Beach Golf Club and Windsor Commons Shopping Center are also worth a visit when you're out sightseeing in Jacksonville Beach.