Large rocks and a sandy beach with sparse vegetation.

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Check prices for these dates

Tonight
Sep 30 - Oct 1
Tomorrow
Oct 1 - Oct 2
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

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Our top choices for Isla Santa María hotels

1. Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
Puerto Ayora
United States
David
NT$8,948
NT$9,843 total
Oct 15 - Oct 16
Angermeyer Waterfront Inn

2. Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
Puerto Ayora
United States
Conrad
NT$17,494
NT$19,292 total
Oct 19 - Oct 20
Finch Bay Galapagos Hotel

3. Hotel Fiesta

Hotel Fiesta
Puerto Ayora
United States
Dayana Cristina
NT$4,440
NT$4,440 total
Oct 3 - Oct 4
Hotel Fiesta

4. Hotel Cucuve

Hotel Cucuve
Puerto Ayora
United States
Sylvia
NT$6,292
NT$6,922 total
Oct 3 - Oct 4
Hotel Cucuve

5. Hotel Ninfa

Hotel Ninfa
Puerto Ayora
United States
Rembert
NT$4,616
NT$4,616 total
Oct 1 - Oct 2
Hotel Ninfa

6. Hotel el descanso del Guia

Hotel el descanso del Guia
Puerto Ayora
United States
Keathan B.
NT$2,097
NT$2,097 total
Oct 15 - Oct 16
Hotel el descanso del Guia

7. Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos
Puerto Ayora
United States
TAKUHIRO
NT$3,233
NT$3,233 total
Oct 25 - Oct 26
Fernandina Hotel & Spa Galápagos

8. El Barranco Galapagos

El Barranco Galapagos
Puerto Ayora
United States
Gloria
NT$8,295
NT$8,295 total
Oct 2 - Oct 3
El Barranco Galapagos

9. Plaza Luna Suites

Plaza Luna Suites
Puerto Ayora
United Kingdom
Daniel
NT$5,574
NT$5,574 total
Oct 2 - Oct 3
Plaza Luna Suites

10. Hotel La Casa de Judy

Hotel La Casa de Judy
Puerto Ayora
Canada
Alexandra
NT$2,294
NT$2,771 total
Oct 1 - Oct 2
Hotel La Casa de Judy

11. Hostal el pinzon

Hostal el pinzon
Puerto Ayora
United States
Edny
NT$1,271
NT$1,271 total
Oct 12 - Oct 13
Hostal el pinzon

12. Mainao

Mainao
Puerto Ayora
United States
Catherine
NT$4,403
NT$4,843 total
Oct 29 - Oct 30
Mainao

13. Ikala Galapagos Hotel

Ikala Galapagos Hotel
Puerto Ayora
United States
Esteban A
NT$8,575
NT$9,432 total
Oct 7 - Oct 8
Ikala Galapagos Hotel

14. Hotel Flamingo

Hotel Flamingo
Puerto Ayora
United States
Jonathan
NT$4,204
NT$4,204 total
Oct 1 - Oct 2
Hotel Flamingo

15. Maidith Galapagos Inn

Maidith Galapagos Inn
Puerto Ayora
United Kingdom
Thomas
NT$4,119
NT$4,119 total
Oct 4 - Oct 5
Maidith Galapagos Inn

16. Posada del Mar

Posada del Mar
Puerto Ayora
United States
Grace
NT$2,631
NT$2,631 total
Oct 1 - Oct 2
Posada del Mar

17. Palo Santo Galapagos Hotel

Palo Santo Galapagos Hotel
Puerto Ayora
United States
Kay
NT$6,864
NT$7,551 total
Oct 1 - Oct 2
Palo Santo Galapagos Hotel

18. Enchanted Galapagos Lodge

Enchanted Galapagos Lodge
Bella Vista
United States
anne
NT$6,410
NT$6,410 total
Oct 25 - Oct 26
Enchanted Galapagos Lodge

19. Capitan Max B&B

Capitan Max B&B
Puerto Ayora
Canada
Christie
NT$2,445
NT$2,445 total
Oct 1 - Oct 2
Capitan Max B&B

20. HOTEL CROSSMAN

HOTEL CROSSMAN
Puerto Ayora
Canada
PENGFEI
NT$2,403
NT$2,403 total
Oct 5 - Oct 6
HOTEL CROSSMAN
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Stay near popular Isla Santa María attractions

A sea turtle swimming underwater.
Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
See properties
Two seals resting on a sandy beach with a rocky shoreline and a sunset in the background.
Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
See properties

Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

See all hotels in Isla Santa María
A seal on a sandy beach with the ocean in the background.
Photo by Edgar Figueiredo

Top Isla Santa María Hotel Reviews

Hotel Coloma Galapagos

Hotel Coloma Galapagos

10/10 Excellent
"Staff was excellent. Breakfast was fresh and tasty"
DOMINIC 2-night trip
Posted 7 hours ago
Hotel Coloma Galapagos
Maidith Galapagos Inn

Maidith Galapagos Inn

10/10 Excellent
"Great hotel and clean rooms. Had a comfortable stay. Breakfast was very good with a decent spread. The hotel staff was friendly and if you’re looking for a personal touch this is the hotel to stay!"
PRIYANK 2-night trip
Posted 7 days ago
Maidith Galapagos Inn
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

10/10 Excellent
"Staff was very helpful, professional and attentive. Outstanding facility and infrastructure anchored with history and legacy of Gus Angermeyer."
Tobin 4-night trip
Posted 9 days ago
Angermeyer Waterfront Inn
Hotel Cucuve

Hotel Cucuve

10/10 Excellent
"This is one of the best properties in the city. The bathroom was the best I saw while visiting the other shops/businesses. The staff is great; they provide a home cooked breakfast everyday and it is a spread for only one person cooking it! Your AC works great, only the room is AC. The bathroom is open air. There is no elevator and the the rooms are either on the 2nd floor or 3rd floor FYI. I would highly recommend this hotel to anyone looking to stay in the Galapagos. This place offered great luxury and enhanced our stay in the islands."
Aaron 6-night trip
Posted 12 days ago
Hotel Cucuve
Posada del Mar

Posada del Mar

10/10 Excellent
"What a wonderful hotel! It is a very central location and 5 mins walk to the pier - so easy to get to your day trip meeting points quickly. It is also located between 2 delicious restaurants. The staff is nice, friendly, and accommodating. The front desk staff offered great suggestions on where to eat, ordered taxis for us, and provided clean beach towels. The breakfast is a perfect start to the day - just $8 per person. Our junior suite was spacious, clean, and comfortable. There is a mini fridge in the room and a wonderful balcony with a patio table. Highly recommend this place to all travelers."
Molly 5-night trip
Posted 2 weeks ago
Posada del Mar
Galapagos Verde Azul

Galapagos Verde Azul

10/10 Excellent
"La amabilidad y calidez del personal. Entrada y salida independiente. Habitación amplia, limpia y cómoda. La ubicación es excelente, cerca de todo."
Catalina 5-night trip
Posted 2 weeks ago
Galapagos Verde Azul
Hotel el descanso del Guia

Hotel el descanso del Guia

8/10 Good
"Muy lejos del centro"
Mónica 2-night trip
Posted 3 weeks ago
Hotel el descanso del Guia
Ikala Galapagos Hotel

Ikala Galapagos Hotel

10/10 Excellent
"I highly recommend this hotel. It is very clean and staff is very friendly. The air conditioning worked great and we were very comfortable in our rooms. The rooftop restaurant is very good and is very scenic. We had breakfast there and wished we would have had dinner there too. Good location. Highly recommend."
Cheryl 1-night trip
Posted 3 weeks ago
Ikala Galapagos Hotel
Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel

10/10 Excellent
"I stayed in room 301 Pretty good view. 201 also has a view of the water. Breakfast was awesome every morning. Clean and close to the main avenue. The staff were excellent."
Franklin 5-night trip
Posted 1 month ago
Acacia Galapagos Boutique Hotel

More cheap stays in Isla Santa María

Carpao Lodge

Carpao Lodge

18 de febrero e isla floreana Puerto Ayora Islas Galápagos
NT$786
NT$786 total
Oct 2 - Oct 3
7/10 Good! (2 reviews)
Carpao Lodge
Hotel Brisas Del Pacifico

Hotel Brisas Del Pacifico

General Rodriguez Puerto Ayora
NT$1,545
NT$1,545 total
Oct 1 - Oct 2
7.6/10 Good! (82 reviews)
Hotel Brisas Del Pacifico
Hostal Costa del Pacifico

Hostal Costa del Pacifico

Avenida Tomas de Berlanga S/N Puerto Ayora Galapagos Islands
NT$1,742
NT$1,742 total
Oct 6 - Oct 7
Hostal Costa del Pacifico
Hostal Sir Francis Drake

Hostal Sir Francis Drake

Av. Baltra y Charles Binford Puerto Ayora Galapagos
NT$2,002
NT$2,002 total
Oct 1 - Oct 2
7.4/10 Good! (78 reviews)
Hostal Sir Francis Drake
Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel

C/ Floreana Y Matazarnos Puerto Ayora Islas Galápagos
NT$6,558
NT$6,558 total
Oct 7 - Oct 8
Acacia Galapagos Boutique Hotel
El Barranco Galapagos

El Barranco Galapagos

Los colonos Puerto Ayora Galapagos
NT$8,295
NT$8,295 total
Oct 2 - Oct 3
El Barranco Galapagos

Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Finch Bay Galapagos Hotel and Maidith Galapagos Inn. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best vacation rentals that Isla Santa María has to offer?
Villa Galapagos: This vacation home near Isla Santa María is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
Where can I learn more about changing or cancelling my trip to Isla Santa María?
For more details about updating your trip to Isla Santa María or cancelling it, click here.
What is staying in Isla Santa María like?
Travelers to Isla Santa María will find plenty to explore and enjoy. There are 219 hotels and other accommodations in larger region. Find out more about Isla Santa María.
What should I see while I'm in Isla Santa María?
Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.
What's the weather like in Isla Santa María?
The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.