Find hotels in Grand Isle, Port St. Joe

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Check prices for these dates

Tonight
Dec 18 - Dec 19
Tomorrow
Dec 19 - Dec 20
This weekend
Dec 19 - Dec 21
Next weekend
Dec 26 - Dec 28

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Our top choices for Grand Isle hotels

Exterior
The Port Inn and Cottages, an Ascend Collection Hotel

The Port Inn and Cottages, an Ascend Collection Hotel

The Port Inn and Cottages, an Ascend Collection Hotel
3.5 star property
Downtown Port St. Joe, 17.9 km from Grand Isle
9.0 out of 10, Wonderful, (404)
"Great staff, clean and comfortable room "
United States
Karen
The price is NT$4,030
NT$4,514 total
includes taxes & fees
Jan 11 - 2026/1/12
The Port Inn and Cottages, an Ascend Collection Hotel
Suite, Multiple Beds, Accessible, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets
MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South
2.5 star property
22.1 km from Grand Isle
8.6 out of 10, Excellent, (694)
"Room was clean, kitchen very clean, hotel staff was very friendly "
United States
Donna
The price is NT$3,453
NT$3,868 total
includes taxes & fees
Dec 28 - Dec 29
MainStay Suites Port Saint Joe South
Lobby
Comfort Suites

Comfort Suites

Comfort Suites
2.5 star property
29 km from Grand Isle
8.6 out of 10, Excellent, (716)
"The staff I encountered were polite and very helpful."
United States
Gerard
The price is NT$2,654
NT$2,868 total
includes taxes & fees
Jan 1 - 2026/1/2
Comfort Suites
Free buffet breakfast
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
2.5 star property
29.1 km from Grand Isle
8.4 out of 10, Very Good, (445)
"We enjoyed our stay."
United States
Lisa
The price is NT$2,992
NT$3,234 total
includes taxes & fees
Dec 23 - Dec 24
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Laptop workspace, iron/ironing board, free cribs/infant beds, free WiFi
Days Inn by Wyndham Panama City/Callaway

Days Inn by Wyndham Panama City/Callaway

Days Inn by Wyndham Panama City/Callaway
2.0 star property
29.4 km from Grand Isle
6.8 out of 10, (477)
"Room was clean and the staff was friendly and helpful."
United States
Billie
The price is NT$1,740
NT$1,881 total
includes taxes & fees
Dec 23 - Dec 24
Days Inn by Wyndham Panama City/Callaway
Exterior
Candlewood Suites Panama City Tyndall AFB by IHG

Candlewood Suites Panama City Tyndall AFB by IHG

Candlewood Suites Panama City Tyndall AFB by IHG
2.5 star property
28.7 km from Grand Isle
9.6 out of 10, Exceptional, (33)
"The room was great, the staff was friendly and helpful. "
United States
Robert
The price is NT$2,775
NT$2,999 total
includes taxes & fees
Dec 27 - Dec 28
Candlewood Suites Panama City Tyndall AFB by IHG
Aerial view
Cape Cottages by Panhandle Getaways

Cape Cottages by Panhandle Getaways

Cape Cottages by Panhandle Getaways
3.5 star property
22.8 km from Grand Isle
10.0 out of 10, Exceptional, (4)
"Brand new, quaint spot with really comfortable beds. "
United States
Anonymous traveler
The price is NT$4,704
NT$17,277 total
includes taxes & fees
Dec 19 - Dec 20
Cape Cottages by Panhandle Getaways
Exterior
Cape San Blas Inn

Cape San Blas Inn

Cape San Blas Inn
3.0 star property
27 km from Grand Isle
9.8 out of 10, Exceptional, (79)
"Great host excellent location we will be back"
United States
Tonianne
Cape San Blas Inn
Desk, laptop workspace, iron/ironing board, free WiFi
Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway
2.5 star property
30.1 km from Grand Isle
6.2 out of 10, (494)
"great stay"
United States
Victor
The price is NT$1,930
NT$2,119 total
includes taxes & fees
Dec 19 - Dec 20
Extended Stay America Select Suites - Panama City - Callaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most.

Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Port St. Joe Marina.

Cape Breezes

While Cape Breezes isn't home to many top sights, T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are some notable places to visit nearby.

Gulf Aire

While Gulf Aire isn't home to many top sights, Saint Joe Beach and Mexico Beach are some notable places to visit nearby.

Waterside Village

Though Waterside Village might not have many top sights, you can venture to the surrounding area to see attractions like Mexico Beach Marina and Mexico Beach.

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

Top Grand Isle Hotel Reviews

Comfort Suites

Comfort Suites

10/10 Excellent
"Staff was friendly. Room was clean and great breakfast variety. "
Lisa 3-night trip
Posted 3 days ago
Comfort Suites

Frequently asked questions

What is Grand Isle like?
Travelers to Mexico Beach's Grand Isle neighborhood will be sure to enjoy a stay in this neighborhood.
How many hotels will I find in Grand Isle?
Expedia has 7 Grand Isle hotels and other accommodations, and one might make a good home base for venturing out into the greater Mexico Beach area.
If I need to cancel my hotel reservation in Grand Isle, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Isle.
Where can I learn more about changing or cancelling my trip to Grand Isle?
For more details about rescheduling or cancelling your trip to Grand Isle, go to https://www.expedia.com/service/.
What is there to do around this Mexico Beach neighborhood?
Mexico Beach Business Center, Mexico Beach, and Mexico Beach Marina are just a few of the places to visit in and around Grand Isle. When you're sightseeing around the area, Saint Joe Beach and Round Timber Island are a couple of other sights to visit.

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