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Our top choices for Glendale hotels

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 3.4 km from Glendale
9.2 out of 10, Wonderful, (1005)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is NT$4,072
NT$4,687 total
includes taxes & fees
Dec 23 - Dec 24
Hyatt House Rochester/Mayo Clinic Area

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 3.9 km from Glendale
8.8 out of 10, Excellent, (892)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is NT$2,525
NT$2,907 total
includes taxes & fees
Dec 25 - Dec 26
Hotel Indigo Rochester – Mayo Clinic Area by IHG

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
10.6 km from Glendale
7.2 out of 10, Good, (1025)
"Staff was courteous and breakfast was well stocked."
United States
Doug
The price is NT$2,216
NT$2,551 total
includes taxes & fees
Dec 24 - Dec 25
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
10.2 km from Glendale
8.8 out of 10, Excellent, (1004)
"Clean rooms, very friendly staff and just all around homey "
United States
Kathy
The price is NT$2,304
NT$2,653 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express Rochester South - Mayo Area by IHG

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
6.6 km from Glendale
9.0 out of 10, Wonderful, (1010)
"We had a wonderful stay!"
United States
Sarah
The price is NT$2,596
NT$2,989 total
includes taxes & fees
Jan 11 - 2026/1/12
Hampton Inn Rochester-South

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest, 4.5 km from Glendale
8.6 out of 10, Excellent, (1005)
"the breakfast and the friendly check-in staff"
United States
Ella
The price is NT$3,888
NT$4,476 total
includes taxes & fees
Dec 23 - Dec 24
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
9.1 km from Glendale
8.4 out of 10, Very Good, (1003)
"Clean room, fun staff."
United States
Thomas
The price is NT$2,790
NT$3,212 total
includes taxes & fees
Jan 11 - 2026/1/12
Country Inn & Suites Rochester South Mayo Clinic

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
6.6 km from Glendale
8.2 out of 10, Very Good, (792)
"Great place to stay. Freindly staff"
United States
joel
The price is NT$2,819
NT$3,245 total
includes taxes & fees
Jan 2 - 2026/1/3
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 4.4 km from Glendale
9.4 out of 10, Exceptional, (963)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is NT$3,440
NT$4,024 total
includes taxes & fees
Dec 26 - Dec 27
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester, 3.7 km from Glendale
8.0 out of 10, Very Good, (1522)
"Clean room, good room service and good breakfast."
United States
Donald
The price is NT$4,008
NT$4,615 total
includes taxes & fees
Dec 29 - Dec 30
Kahler Inn and Suites - Mayo Clinic Area

Aspen Suites

Aspen Suites
3.0 star property
4.6 km from Glendale
9.0 out of 10, Wonderful, (695)
"Room was clean and inviting and staff always willing to help"
United States
Maria del Carmen
The price is NT$4,892
NT$5,913 total
includes taxes & fees
Jan 9 - 2026/1/10
Aspen Suites

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
6.2 km from Glendale
8.2 out of 10, Very Good, (1146)
"Good price, room clean, descent breakfast. I have stayed here several time"
United States
Amy M
The price is NT$2,303
NT$2,652 total
includes taxes & fees
Dec 26 - Dec 27
AmericInn by Wyndham Rochester Near Mayo Clinic

Aspen Select

Aspen Select
3.5 star property
4.6 km from Glendale
8.4 out of 10, Very Good, (1010)
"Great location for hospital stay"
United States
David D
Aspen Select

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park, 4.8 km from Glendale
8.8 out of 10, Excellent, (765)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is NT$2,746
NT$3,161 total
includes taxes & fees
Dec 25 - Dec 26
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
6 km from Glendale
9.2 out of 10, Wonderful, (1003)
"Pool was nice "
Canada
Jesse
The price is NT$2,821
NT$3,248 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn & Suites Rochester-North

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 3.7 km from Glendale
8.8 out of 10, Excellent, (1006)
"Convenient, clean location and friendly staff"
United States
Kaushika
The price is NT$3,551
NT$4,088 total
includes taxes & fees
Dec 23 - Dec 24
Brentwood Inn & Suites

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester, 3.7 km from Glendale
8.4 out of 10, Very Good, (1837)
"It was just perfect!"
United States
Shannon
The price is NT$4,232
NT$4,873 total
includes taxes & fees
Dec 24 - Dec 25
Kahler Grand Hotel

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 4.7 km from Glendale
9.2 out of 10, Wonderful, (770)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is NT$2,651
NT$3,052 total
includes taxes & fees
Dec 24 - Dec 25
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
6.4 km from Glendale
9.6 out of 10, Exceptional, (882)
"Great stay,clean and friendly"
United States
Janet
The price is NT$3,597
NT$4,142 total
includes taxes & fees
Dec 28 - Dec 29
Home2 Suites by Hilton Rochester Mayo Clinic Area

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
6.7 km from Glendale
9.0 out of 10, Wonderful, (898)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is NT$2,161
NT$2,488 total
includes taxes & fees
Jan 4 - 2026/1/5
Econo Lodge Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Glendale

Find the best Glendale areas and neighborhoods for the activities you enjoy most.

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Slatterly Park

Slatterly Park might not have many top sights, but Rochester Art Center and Soldiers Field Veterans Memorial are two attractions nearby that you can check out.

East Side Pioneers

If you're spending some time in East Side Pioneers, Rochester Art Center and Rochester Civic Theater are top sights worth seeing.

Top Glendale Hotel Reviews

Frequently asked questions

What is Glendale like?
Travelers will be sure to enjoy their time in Rochester's Glendale neighborhood.
If I need to cancel my hotel reservation in Glendale, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get top deals in Glendale.
Where can I learn more about changing or cancelling my trip to Glendale?
For additional details about rescheduling or cancelling your trip to Glendale, head over to our customer service page.
What is there to do around this Rochester neighborhood?
National Volleyball Center, Rochester Recreation Center, and Minnesota Children's Museum are just a few of the places to visit in and around Glendale. While you're out sightseeing, Quarry Hill Nature Center and Assisi Heights are a couple of additional sights to visit in Rochester.

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