A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Southern Indiana 4 Stars Hotels

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Check availability on Southern Indiana 4 Star Hotels

Tonight
Sep 5 - Sep 6
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Sep 6 - Sep 7
Next weekend
Sep 11 - Sep 13
In two weeks
Sep 18 - Sep 20

Our top choices for Southern Indiana 4-star hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Jacob
NT$5,062
NT$5,955 total
includes taxes & fees
Sep 6 - Sep 7
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A lobby with a marble floor, a reception desk, and a large chandelier.
A modern interior with a fireplace, bookshelves, and seating areas.

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Kara
NT$6,303
NT$7,416 total
includes taxes & fees
Sep 7 - Sep 8
Omni Louisville Hotel
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

3. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
Rachel
NT$4,248
NT$4,998 total
includes taxes & fees
Sep 7 - Sep 8
The Brown Hotel
A spacious lobby with a central escalator, comfortable seating areas, and modern lighting fixtures.
A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.
A modern lobby with a central seating area, an escalator, and a staircase.
An outdoor seating area with wicker furniture, wooden tables, and large lamps.

4. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Arnetta
NT$4,025
NT$4,735 total
includes taxes & fees
Sep 7 - Sep 8
Hyatt Regency Louisville
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern hotel room with a living area, a dining area, and a bedroom.
A hotel dining area with long tables, booths, and a bar.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.

5. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Spencer
NT$4,644
NT$5,464 total
includes taxes & fees
Oct 4 - Oct 5
Embassy Suites Louisville Downtown
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.
A bedroom with a bed, a chair, a TV, and a window with curtains.
A brightly lit grocery store with yellow shelving and a central checkout counter.

6. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Rebekah
NT$4,528
NT$5,327 total
includes taxes & fees
Sep 7 - Sep 8
Hotel Genevieve part of JdV by Hyatt
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

7. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Lisa
NT$6,296
NT$7,408 total
includes taxes & fees
Sep 6 - Sep 7
Louisville Marriott Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

8. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Candice
NT$5,621
NT$6,772 total
includes taxes & fees
Oct 4 - Oct 5
21c Museum Hotel Louisville
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".
A building with a sign reading "THE GRADY" at the entrance.
A modern restaurant interior with a staircase, round tables, and a brick wall.

9. The Grady

The Grady
Downtown Louisville
United States
Garrett
NT$4,888
NT$5,752 total
includes taxes & fees
Sep 13 - Sep 14
The Grady
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
A bar with shelves of liquor bottles and a bartender preparing drinks.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

10. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Jasmine
NT$7,246
NT$8,525 total
includes taxes & fees
Sep 6 - Sep 7
Hotel Distil, Autograph Collection
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern hotel room with a large bed, a city view, and a unique headboard design.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Breeana
NT$6,296
NT$7,409 total
includes taxes & fees
Sep 7 - Sep 8
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern living room with a fireplace, a coffee table with books, a jar of cookies, and a plate of cookies.
A modern building with a prominent sculpture in front, large glass windows, and a brightly lit entrance.
An outdoor pool area with lounge chairs, a fire pit, and a building with brick walls and windows.
A breakfast tray with croissants, fruit, coffee, and juice on a table by a window with a city view.

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
Downtown Evansville
United States
Jennifer
NT$3,113
NT$3,580 total
includes taxes & fees
Oct 4 - Oct 5
DoubleTree by Hilton Evansville
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.
A grand staircase with ornate railings and a marble floor, leading to a high-ceilinged lobby with decorative moldings and a chandelier.
A grand lobby with marble floors, a staircase, and a reception desk.
A spacious living room with a fireplace, wooden paneling, a television, and a blue sofa.

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Jennifer
NT$4,907
NT$5,774 total
includes taxes & fees
Sep 7 - Sep 8
Seelbach Hilton Louisville Downtown
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.
A covered porch with a brick wall, a wooden door, and a hanging light fixture.
A long table set with white tablecloths, gold chargers, and clear glassware.
A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.

14. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
Ronald
NT$2,856
NT$3,227 total
includes taxes & fees
Sep 7 - Sep 8
The Pepin Mansion Historic B&B
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

15. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Brad
NT$3,039
NT$5,180 total
includes taxes & fees
Sep 8 - Sep 9
Stellar Suites
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.
A reception desk with a dark wood finish, a sign reading "stay apt SUITES", and a telephone.

16. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
United States
Chauntel
NT$4,276
NT$4,832 total
includes taxes & fees
Sep 12 - Sep 13
stayAPT Suites Louisville North-Clarksville
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.
A gym with exercise equipment, mirrors, and a TV screen.
A multi-story residential building with balconies, a brick facade, and large windows.
A modern living room with a dining area, a blue sofa, a ceiling fan, and a view of a balcony.

17. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Jennifer
NT$2,974
NT$7,125 total
includes taxes & fees
Sep 7 - Sep 8
CozySuites at Nulu
A modern lounge with leather sofas, a coffee table, and a view of a classical building.
A modern living room with a leather sofa, two coffee tables, and a chessboard. There are shelves with bottles and glasses, and a large window on the right.
A modern interior with a wooden dining table, leather sofas, and a bar area with shelves.
A building with a sign reading "Pursuit Spirits Co." and a large window display.

18. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
A large, multi-story building with a prominent tower and multiple windows.
A cozy seating area with two leather armchairs and a small round table. A table lamp and a wine glass are on the table.
A large outdoor swimming pool with a Ferris wheel in the background.
A dining table set with placemats, folded napkins, cutlery, and a coffee cup.

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.
A living room with a sofa, a coffee table, and a ceiling fan. There is a dining area with a table and chairs.
A kitchen with a black refrigerator, a dining area with a table and chairs, and a living room with a blue sofa.
A two-story brick house with a garage, a front door, and a small front yard with a lawn and a few shrubs.

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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A riverboat with multiple decks and passengers, docked near a bridge.

Top Southern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.
  • Search for the lowest price from NT$3,227
What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

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