A vineyard with rows of grapevines.

Find hotels in Santa Cruz from NT$1,043

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Cruz hotels

1. Santa Cruz Plaza

Santa Cruz Plaza
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (376 reviews)
"Unfortunately our room faced the plaza and loud band until almost midnight! Also at 3 am we were awakened by loud tapping noise that lasted about 20 minutes"
United States
Hector
The price is NT$3,884
NT$3,884 total
Nov 8 - Nov 9
Santa Cruz Plaza

2. Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (147 reviews)
"Loved the rustic hotel and Mauricio and Carla are awesome hosts! Great location and an amazing place to stay. Highly recommended. "
United States
Orlando
The price is NT$2,007
NT$2,007 total
Oct 28 - Oct 29
Hotel Boutique Vendimia Premium

3. TerraViña

TerraViña
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (220 reviews)
"Great location, friendly staff ."
United Kingdom
DARREN
The price is NT$5,214
NT$5,214 total
Oct 28 - Oct 29
TerraViña

4. Hotel Cava Colchagua

Hotel Cava Colchagua
4.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (177 reviews)
"Interesting and beautiful place to stay. Barrel rooms are comfortable. Staff are very pleasant and accomodating. Food at the restaurant was fantastic. Shower was not the best."
Canada
Anonymous traveler
The price is NT$4,361
NT$4,361 total
Nov 15 - Nov 16
Hotel Cava Colchagua

5. Hotel Vendimia Parador

Hotel Vendimia Parador
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (90 reviews)
"A lovely hotel run by a lovely family!"
United States
Amihai
The price is NT$1,597
NT$1,597 total
Nov 22 - Nov 23
Hotel Vendimia Parador

6. La Perla Hotel

La Perla Hotel
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (116 reviews)
"Excellent Staff, excellent facilities, and an excellent sleep in a very quiet location."
Canada
Nancy
The price is NT$2,874
NT$4,520 total
Oct 30 - Oct 31
La Perla Hotel

7. Casa Calfu

Casa Calfu
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (67 reviews)
"Charming place ! "
France
Ruxandra
The price is NT$2,621
NT$2,621 total
Oct 28 - Oct 29
Casa Calfu

8. Hotel Boutique Grand Cru

Hotel Boutique Grand Cru
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (20 reviews)
"Excellent staff, beautiful rooms and amenities "
United States
Jonathan
The price is NT$2,962
NT$2,962 total
Nov 1 - Nov 2
Hotel Boutique Grand Cru

9. Hostal Vida 2000

Hostal Vida 2000
2.5 star property
Santa Cruz
5.4 out of 10, (3 reviews)
"Simple clean place with wonderful hosts that were very accommodating. Breakfast was set up beautifully with plenty of food."
United States
Kati
The price is NT$1,043
NT$1,043 total
Oct 28 - Oct 29
Hostal Vida 2000

10. Colchagua Tiny Lodge

Colchagua Tiny Lodge
3.5 star property
Santa Cruz
9.8 out of 10, Exceptional, (11 reviews)
"Cute lodge with friendly staff that helps you to your cozy room- sets up your hot tub and brings an amazing basket for breakfast! Can’t wait to go back "
United States
Jonathan
The price is NT$5,333
NT$5,333 total
Oct 28 - Oct 29
Colchagua Tiny Lodge

11. Noi Blend Colchagua

Noi Blend Colchagua
3.0 star property
Palmilla
8.8 out of 10, Excellent, (159 reviews)
"The hotel staff were great. Lovely place to visit and the surroundings were astonishing, totally recommended."
United States
Barbara
The price is NT$5,449
NT$5,449 total
Oct 28 - Oct 29
Noi Blend Colchagua

12. Vik Chile

Vik Chile
5.0 star property
San Vicente
9.2 out of 10, Wonderful, (228 reviews)
"Lovely location and we had a great time. The food was excellent and the variety of activities great."
United Kingdom
Andre
The price is NT$22,788
NT$22,788 total
Oct 28 - Oct 29
Vik Chile

13. Hotel Ontiveros

Hotel Ontiveros
3.5 star property
San Fernando
9.6 out of 10, Exceptional, (30 reviews)
"Quiet location on the outskirts of the city. Very nice hotel and room. "
Canada
Gordon
The price is NT$2,087
NT$2,087 total
Oct 29 - Oct 30
Hotel Ontiveros

14. Hotel Viña La Playa

Hotel Viña La Playa
3.5 star property
Peralillo
8.4 out of 10, Very good, (19 reviews)
"Nice place, if you want to rest this is the place"
Mexico
Manuel
The price is NT$6,934
NT$6,934 total
Oct 30 - Oct 31
Hotel Viña La Playa

15. Anita y Tomás - Bed and Breakfast

Anita y Tomás - Bed and Breakfast
3.5 star property
O HIGGINS REGION
The price is NT$3,226
NT$3,226 total
Oct 28 - Oct 29
Anita y Tomás - Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Nestled in the heart of wine country, Santa Cruz invites visitors to taste world-class Colchagua Valley wines at family-owned vineyards. Museum of Colchagua showcases impressive pre-Columbian artifacts while the Plaza de Armas offers local crafts and regional foods on weekends.

A vineyard with rows of grapevines, terraced fields, and mountains in the background.

Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

Find out more about Santa Cruz

Top reasons to visit Santa Cruz

  • Outdoor Adventures: Santa Cruz boasts scenic hiking trails, coastal walks, and surfing opportunities, perfect for adventure seekers.
  • Rich History and Culture: Explore historic buildings and museums that showcase the region's cultural heritage and stories.
  • Charming Vineyards: Relax amid picturesque vineyards, offering wine tours and tastings that highlight local flavors.
  • Delicious Food Tours: Savor the culinary delights of the region through guided food tours featuring local cuisine.
  • Diverse Accommodations: Enjoy a range of lodging options, from cozy bed & breakfasts to luxurious retreats.

Find great hotels in and around Santa Cruz

Discover the charm of Santa Cruz, O'Higgins Region, with a variety of hotel accommodations designed to meet every traveler's needs. From winery-themed retreats to relaxing spa experiences, Santa Cruz offers a perfect blend of comfort and convenience. Whether you're seeking a cozy bed & breakfast or a business-friendly hotel, you'll find an array of options to enhance your stay. Explore the best Santa Cruz hotels and enjoy memorable experiences in this picturesque destination.

  • Santa Cruz Plaza: Santa Cruz Plaza is a welcoming 4-star hotel that boasts a family-friendly environment and an adventure-themed experience right in the heart of Santa Cruz. With a guest rating of 8.8 out of 10, this hotel is ideal for families seeking a blend of excitement and comfort. The property offers a variety of adventure sports options nearby, including hiking, rafting, and kayaking, catering to active travelers. Families will appreciate the amenities designed for children, such as free cribs and a complimentary kids’ club, ensuring a fun and safe stay for younger guests.
  • Vik Chile: A luxurious 5-star retreat, Vik Chile is set about 16km from Santa Cruz and is perfect for travelers looking for an upscale adventure and winery-themed getaway. With an impressive guest rating of 9.2 out of 10, this hotel offers a remarkable experience surrounded by stunning vineyards. Guests can enjoy various adventure activities, including onsite biking and horseback riding. The accessible winery vineyard enhances the experience, providing opportunities for tastings and vineyard tours, making it a remarkable choice for wine enthusiasts and luxury seekers alike.
  • TerraViña: TerraViña is a charming 3-star hotel located in Santa Cruz, favored by couples seeking a romantic and adventurous winery experience. With a guest rating of 9.2 out of 10, this hotel features special romance packages that include spa services and pool access for a relaxing getaway. Couples can enjoy the delightful food and beverage options, including champagne service and private winery tours. The proximity to various outdoor adventures, like hiking and mountain biking, allows guests to indulge in both romance and exploration during their stay.

Where to stay near Santa Cruz

Santa Cruz, nestled in the O'Higgins Region of Chile, offers a captivating blend of romance, outdoor adventures, and entertainment. Explore the charming city, where you can enjoy a relaxing atmosphere amidst vineyards. Nearby, discover lively resorts reminiscent of Santa Cruz, California, or unwind at the scenic Playa in South Tenerife, Canary Islands. Whether you seek luxury or adventure, Santa Cruz promises a memorable vacation filled with diverse experiences to delight every traveler.

  • Colchagua Valley Wine Route: Just 10km from Santa Cruz, the Colchagua Valley Wine Route is a must-visit for wine enthusiasts and nature lovers alike. This picturesque area boasts a moderate seasonal influx of visitors, primarily peaking from January to March. Known for its romantic and outdoor experiences, travelers can enjoy hiking trails and ski fields, along with stunning views of vineyards. The local attractions include beautiful beaches and event venues that cater to families and groups, making it a well-rounded destination for relaxation and entertainment.
  • Cunaco: Located 6km from Santa Cruz, the charming village of Cunaco offers a unique glimpse into local life. With a similar seasonal visitor pattern peaking between January and March, Cunaco is perfect for those seeking romantic getaways and outdoor activities. Enjoy skiing and exploring nearby historical museums that showcase the region's rich culture. The village's tranquil atmosphere makes it an ideal spot for unwinding while still being close to the hustle and bustle of Santa Cruz.
  • Palmilla: Situated 13km away from Santa Cruz, Palmilla is a vibrant city that welcomes travelers year-round, with peak visitation in February to March and September. Known for its romantic ambiance and outdoor attractions, Palmilla offers hiking trails and ski opportunities for adventure seekers. Relax at the beautiful beaches or attend events at local conference venues and experience the captivating coastal landscapes. Palmilla perfectly combines leisure and excitement, making it a fantastic addition to your travel itinerary.

Things to do in Santa Cruz

Shopping

In Santa Cruz, you can explore local shops for unique gifts and souvenirs. If you're up for a drive, visit Plaza de Armas in nearby towns for artisan markets and local crafts, adding a special touch to your shopping experience.

Recreation

Termas de Chillán offers rejuvenating hot springs surrounded by stunning mountain views, perfect for soaking and relaxation. Nearby, the Colchagua Valley invites you to enjoy wine tasting tours, scenic vineyards, and leisurely hikes, providing a delightful blend of wellness and outdoor exploration.

Adventure

In Santa Cruz, explore the breathtaking Colchagua Valley on a wine tour, sampling exquisite local wines while surrounded by picturesque vineyards. For thrill-seekers, embark on a mountain biking adventure through scenic trails, offering diverse landscapes and exhilarating rides that highlight the region's natural beauty.

Nightlife

Explore the lively atmosphere at La Casona del Vino, where you can enjoy a wide selection of Chilean wines and delicious tapas. For dancing, head to Sala de Eventos Santa Cruz, featuring local DJs and a vibrant crowd that keeps the energy high into the night.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

To save money on your trip to Santa Cruz, consider visiting in March, August, or December when prices are lower. Book your hotel about a month in advance, and aim for Tuesday stays, the cheapest day. Use Expedia's search tool to compare rates and find last-minute deals, especially indicated by a green label. Consider booking a package that combines your hotel, flights, and activities for extra savings. Additionally, explore free activities in the area to maximize your experience without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are March, August and December, where the prices are slightly lower. This is in comparison to April to May and July, where prices are slightly higher.
  • The best time to book a hotel: Book your hotel in Santa Cruz about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Tuesday. The most expensive day to stay in Santa Cruz is Sunday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your options based on your budget, preferred location, and the type of hotel you desire. To find the best prices and deals, arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Santa Cruz with your flights and activities by booking an Expedia package.

Find the best attractions in and around Santa Cruz

Santa Cruz, nestled in the O'Higgins Region of Chile, offers a perfect blend of romance, entertainment, and outdoor activities. Visitors can explore various attractions, historic buildings, and history museums that provide a rich cultural experience. Don't miss the chance to visit local highlights like the Santa Cruz de Tenerife and the Santa Cruz Wharf, adding unique charm to your vacation.

  • Colchagua Campo y Vino: Experience the serene beauty of the Colchagua Valley at this attraction, where you can indulge in relaxing excursions and enjoy the luxury of the surrounding vineyards. Discover local wines and the picturesque landscapes that make this region famous.
  • Hacienda El Huique: Located 13km from Santa Cruz, this historic building offers a glimpse into Chile's rich cultural heritage. Wander through its charming grounds and immerse yourself in the fascinating history that shaped the area.
  • Plaza de Armas: Situated in the heart of Santa Cruz, this vibrant square is a hub of city life and culture. Enjoy the lively atmosphere, admire local architecture, and engage with the community at various events and markets.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in January, when visitor numbers are slightly high and weather is sunny with no rain. The coolest average temperature in Santa Cruz falls in July, visitor numbers are average and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January72.5°F (22.5°C)No RainSunnySlightly HighAverage
February71.6°F (22.0°C)No RainSunnySlightly HighAverage
March68.4°F (20.2°C)No RainSunnySlightly HighSlightly Low
April61.5°F (16.4°C)No RainSunnyAverageSlightly High
May55.2°F (12.9°C)Light RainMostly SunnySlightly LowSlightly High
June49.6°F (9.8°C)Light RainMostly SunnyAverageSlightly High
July47.5°F (8.6°C)Light RainMostly SunnyAverageAverage
August50.0°F (10.0°C)Light RainMostly SunnyAverageAverage
September53.2°F (11.8°C)Light RainMostly SunnyAverageAverage
October57.9°F (14.4°C)No RainSunnySlightly LowAverage
November64.6°F (18.1°C)No RainSunnySlightly LowSlightly Low
December69.3°F (20.7°C)No RainSunnyAverageSlightly Low

The nearest major airports for your trip to Santa Cruz

Traveling to Santa Cruz, O'Higgins Region, Chile is convenient via Santiago's Arturo Merino Benitez Airport (SCL), located 148km away. A few excellent hotel options near the airport include The Singular Santiago, a luxurious 5-star hotel only 14km from SCL, offering a 24-hour airport shuttle service and various transportation options. NH Ciudad de Santiago, a 4.5-star hotel located 16km away, also provides on-request airport shuttle services. Another 4.5-star option, Luciano K Hotel, is similarly situated 16km from SCL, offering shuttle services with applicable fees. These hotels ensure seamless access to the airport for a smooth travel experience.

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Based on our traveler data, Santa Cruz Plaza is one of the top choices for your stay. This hotel offers a full-service spa and a restaurant. Other good choices for your trip include Hotel Cava Colchagua and La Perla Hotel. See all available top hotels, or vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To access more information about changing or cancelling your trip to Santa Cruz, head over to our customer service page.
What's the best budget-friendly hotel in Santa Cruz?
Based on our traveler reviews, Hostal Gomero is a top choice for a less expensive stay. Other choices to stay on the cheap include Hostal Cepa Noble and Casa Suiza - Hostel. View all budget hotels in Santa Cruz.
What's the best hotel for families in Santa Cruz?
Santa Cruz Plaza is a hotel with an outdoor pool and a free kids' club, and it's a top choice on Expedia for families. Kids of all ages will also enjoy a visit to Colchagua Campo y Vino. Find more child-friendly accommodations in Santa Cruz.
What's the best pet-friendly place to stay in Santa Cruz?
Hotel Vendimia Parador is a top hotel for people traveling with their pets, and offers an indoor pool and an outdoor pool for its human guests. Two other good options for you and your pet's trip include El Refugio de Santa Cruz and Hotel Hoja de Parra. See more pet-friendly hotel accommodations in Santa Cruz.
Where is the best place to stay close to Plaza de Armas?
Adjacent to Plaza de Armas, Santa Cruz Plaza is one of the top choices for your stay based on our traveler data, and this 4-star hotel offers a full-service spa and a restaurant. Other good choices close by include Intown Apart Santa Cruz and Tierra y Vino.
What about the best place to stay close to Museo de Colchagua?
One of the top choices for your stay is Santa Cruz Plaza, located next to Museo de Colchagua, and this 4-star hotel offers a full-service spa and a restaurant. La Perla Hotel and Tierra y Vino are two other good choices in the immediate area.
What's the best luxury hotel in Santa Cruz?
Vibo Wine Lodge is a luxury lodge with a winery and private balconies, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Hotel Vendimia Parador is a top hotel with an indoor pool, an outdoor pool, and free WiFi. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Santa Cruz Plaza is a top spa hotel featuring a rooftop terrace, a 24-hour fitness center, a free kid's club, and a bar. Treat yourself to a facial, body scrub, or hydrotherapy at the onsite spa. Other popular spa hotels in Santa Cruz include Hotel Cava Colchagua and Hostal Vida 2000. See all spa hotels in Santa Cruz.
What is the best accommodation for staying close to Arturo Merino Benitez Airport (SCL)?
Holiday Inn Santiago - Airport Terminal is a popular 3.5-star hotel featuring free extended parking and a restaurant. It's located a short 0.1 mi (0.2 km) from Arturo Merino Benitez Airport. Other good choices near the airport include Hotel Diego de Almagro Aeropuerto - Santiago and City Express Santiago Aeropuerto.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the wineries, local tours, and restaurants. Tourists can also enjoy so much more including its casinos. In Santa Cruz, there are 36 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Wine tasting is a great activity, and Lapostolle Clos Apalta Winery is one place to visit. A couple of additional sights to add to your agenda are Casino Colchagua and Colchagua Campo y Vino. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather like in Santa Cruz?
The hottest months are usually January and February with an average temp of 70°F, while the coldest months are July and August with an average of 50°F. Average annual precipitation for Santa Cruz is 29 inches.